Results 11 to 20 of about 31,578 (263)

Acquired von Willebrand syndrome: focused for hematologists

Haematologica, 2020
The acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. However, unlike the inherited disease, AvWS occurs in persons with no personal and family history of ...
Massimo Franchini, Pier Mannuccio Mannucci   +1 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Prognostic value of von Willebrand factor in clinical practice

Акушерство, гинекология и репродукция, 2022
The von Willebrand factor (vWF) is a multimeric plasma glycoprotein, which quantification has important prognostic value. The current literature review demonstrates a relationship between the disease severity and vWF level.
K. N. Grigoreva, V. O. Bitsadze, J. Kh. Khizroeva, V. I. Tsibizova, M. V. Tretyakova, D. V. Blinov, L. L. Pankratyeva, N. R. Gashimova, F. E. Yakubova, A. S. Antonova, J.-C. Gris, I. Elalamy, A. D. Makatsariya   +12 more
doaj   +1 more source

Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report

Caspian Journal of Neurological Sciences, 2022
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani, Shirin Haghighat, Maryam Poursadeghfard   +2 more
doaj  

بررسی درصد فراوانی بیماری von Willebrand در زنان با خونریزی شدید قاعدگی

مجله دانشکده پزشکی اصفهان, 2018
مقدمه: شیوع بیماری von Willebrand در بیماران دارای خونریزی شدید قاعدگی، در مطالعات غیر بومی و بسته به جمعیت مورد مطالعه، بین 20-5 درصد برآورد شده است. شیوع این بیماری در ایران تنها در یک مطالعه بررسی شده است.
Fariborz Mokarian, Alireza Sadeghi, Fariba Behnamfar, Arman Soorani, Elham Moazam   +4 more
doaj   +1 more source

The Expression of von Willebrand Factor-Binding Protein Determines Joint-Invading Capacity of Staphylococcus aureus, a Core Mechanism of Septic Arthritis

mBio, 2020
Septic arthritis, one of the most dangerous joint diseases, is predominantly caused by Staphylococcus aureus. In contrast, coagulase-negative staphylococci are rarely found in septic arthritis. We hypothesize that coagulases released by S.
Manli Na, Zhicheng Hu, Majd Mohammad, Mariana do Nascimento Stroparo, Abukar Ali, Ying Fei, Anders Jarneborn, Peter Verhamme, Olaf Schneewind, Dominique Missiakas, Tao Jin   +10 more
doaj   +1 more source

Comprehensive Analyses of Coagulation Parameters in Patients with Vascular Anomalies

Biomolecules, 2022
Background: Vascular anomalies comprise a diverse group of rare diseases with altered blood flow and are often associated with coagulation disorders. The most common example is a localized intravascular coagulopathy in venous malformations leading to ...
Friedrich G. Kapp, Cedric Schneider, Annegret Holm, Hannah Glonnegger, Charlotte M. Niemeyer, Jochen Rößler, Barbara Zieger   +6 more
doaj   +1 more source

von Willebrand Disease

Medicine, 1997
Considerable progress has been made in characterizing the specific molecular defects responsible for the heterogeneous disorder known as von Willebrand disease (VWD). A large number of molecular defects have been identified and precise characterization may now be possible in the majority of type 2A, type 2B, type 2N, and potentially also type 3 VWD ...
W C, Nichols, D, Ginsburg
openaire   +2 more sources

Shear-induced acquired von Willebrand syndrome: an accomplice of bleeding events in adults on extracorporeal membrane oxygenation support

Frontiers in Cardiovascular Medicine, 2023
Extracorporeal membrane oxygenation (ECMO) is an increasingly acceptable life-saving mechanical assistance system that provides cardiac and/or respiratory support for several reversible or treatable diseases.
Haiwang Wang, Haiwang Wang, Haiwang Wang, Duo Li, Duo Li, Duo Li, Yuansen Chen, Yuansen Chen, Yuansen Chen, Ziquan Liu, Ziquan Liu, Ziquan Liu, Yanqing Liu, Yanqing Liu, Yanqing Liu, Xiangyan Meng, Xiangyan Meng, Xiangyan Meng, Haojun Fan, Haojun Fan, Haojun Fan, Shike Hou, Shike Hou, Shike Hou   +23 more
doaj   +1 more source

Aptamer-based applications for cardiovascular disease

Frontiers in Bioengineering and Biotechnology, 2022
Cardiovascular disease (especially atherosclerosis) is a major cause of death worldwide, and novel diagnostic tools and treatments for this disease are urgently needed. Aptamers are single-stranded oligonucleotides that specifically recognize and bind to
Xinyuan Chen, Yue Ma, Yuquan Xie, Jun Pu
doaj   +1 more source