Results 11 to 20 of about 6,412,465 (299)

Von Willebrand Disease in the elderly: clinical perspectives

Clinical Interventions in Aging, 2018
John Chapin Department of Hematology, Shire, Lexington, MA, USA Abstract: Von Willebrand disease (VWD) is an inherited bleeding disorder that affects up to 1% of the population. In most cases, VWD results from a mutation in the von Willebrand Factor (VWF)
Chapin J
doaj   +1 more source

Acquired von Willebrand syndrome: focused for hematologists [PDF]

Haematologica, 2020
The acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. However, unlike the inherited disease, AvWS occurs in persons with no personal and family history of ...
Massimo Franchini, Pier Mannuccio Mannucci   +1 more
doaj   +2 more sources

Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women [PDF]

, 2003
Low socioeconomic status (SES) and psychological stress are associated with increased risk of coronary heart disease, and both may influence haemostatic responses.
Lowe, G.D.O., Kunz-Ebrecht, S., Rumley, A., Steptoe, A.   +3 more
core   +9 more sources

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]

, 2009
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Hársfalvi, Jolán, Molvarec, Attila, Gombos, Tímea, Udvardy, Miklós László, Cervenak, László, Derzsy, Zoltán, Prohászka, Zoltán, Rigó, János, Bõze, Tamás, Makó, Veronika   +9 more
core   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Hársfalvi, Jolán, Gombos, Tímea, Cervenak, László, Jánoskuti, Lívia, Förhécz, Zsolt, Prohászka, Zoltán, Papassotiriou, Jana, Makó, Veronika, Pozsonyi, Zoltán, Kunde, Jan   +10 more
core   +1 more source

Prognostic value of von Willebrand factor in clinical practice

Акушерство, гинекология и репродукция, 2022
The von Willebrand factor (vWF) is a multimeric plasma glycoprotein, which quantification has important prognostic value. The current literature review demonstrates a relationship between the disease severity and vWF level.
K. N. Grigoreva, V. O. Bitsadze, J. Kh. Khizroeva, V. I. Tsibizova, M. V. Tretyakova, D. V. Blinov, L. L. Pankratyeva, N. R. Gashimova, F. E. Yakubova, A. S. Antonova, J.-C. Gris, I. Elalamy, A. D. Makatsariya   +12 more
doaj   +1 more source

Temperature-Dependence of Weibel-Palade Body Exocytosis and Cell Surface Dispersal of von Willebrand Factor and Its Propolypeptide [PDF]

, 2011
Background: Weibel-Palade bodies (WPB) are endothelial cell (EC) specific secretory organelles containing Von Willebrand factor (VWF). The temperature-dependence of Ca2+-driven WPB exocytosis is not known, although indirect evidence suggests that WPB ...
Hewlett, L, Matthew J. Hannah, Carter, T, David Ogden, Hannah, MJ, Matthew J Hannah, Mashanov, G, Gregory Mashanov, Zupančič, G, Knipe, L, Tom Carter, Laura Knipe, Gregor Zupančič, Ogden, D, Lindsay Hewlett, Zupančič Gregor, Hannah, Matthew J., Ogden, David, Hewlett, Lindsay, Carter Tom, Hannah Matthew J., Knipe, Laura, Mashanov, Gregory, Ogden David, Zupančič, Gregor, Hewlett Lindsay, Carter, Tom D., Mashanov Gregory, Knipe Laura   +28 more
core   +1 more source

Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report

Caspian Journal of Neurological Sciences, 2022
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani, Shirin Haghighat, Maryam Poursadeghfard   +2 more
doaj  

بررسی درصد فراوانی بیماری von Willebrand در زنان با خونریزی شدید قاعدگی

مجله دانشکده پزشکی اصفهان, 2018
مقدمه: شیوع بیماری von Willebrand در بیماران دارای خونریزی شدید قاعدگی، در مطالعات غیر بومی و بسته به جمعیت مورد مطالعه، بین 20-5 درصد برآورد شده است. شیوع این بیماری در ایران تنها در یک مطالعه بررسی شده است.
Fariborz Mokarian, Alireza Sadeghi, Fariba Behnamfar, Arman Soorani, Elham Moazam   +4 more
doaj   +1 more source