Results 11 to 20 of about 147,268 (335)
Acquired von Willebrand syndrome: focused for hematologists
Haematologica, 2020 The acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder with laboratory findings similar to those of inherited von Willebrand disease. However, unlike the inherited disease, AvWS occurs in persons with no personal and family history of ...
Massimo Franchini +1 more
doaj +4 more sources
Regulation of VWF (Von Willebrand Factor) in Inflammatory Thrombosis
Arteriosclerosis, Thrombosis, and Vascular Biology, 2022 Increasing evidence indicates that inflammation promotes thrombosis via a VWF (von Willebrand factor)-mediated mechanism. VWF plays an essential role in maintaining the balance between blood coagulation and bleeding, and inflammation can lead to aberrant
Harm Jan Bogaard, Jurjan Aman
exaly +3 more sources
Acquired von Willebrand syndrome: An update
American Journal of Hematology, 2007 Acquired von Willebrand syndrome (aVWS) is a rare bleeding disorder with laboratory findings similar to those for congenital von Willebrand disease (VWD).
Massimo Franchini
exaly +3 more sources
Acquired von Willebrand Syndrome Associated with Cardiovascular Diseases
Journal of Atherosclerosis and Thrombosis, 2019 The blood glycoprotein von Willebrand factor (VWF) plays an important role in hemostasis and thrombosis. VWF is produced and secreted as large multimers by endothelial cells and megakaryocytes.
Hisanori Horiuchi +2 more
exaly +2 more sources
Von Willebrand Factor, Angiodysplasia and Angiogenesis
Mediterranean Journal of Hematology and Infectious Diseases, 2013 The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes.
A. Randi, M. Laffan, R. Starke
semanticscholar +3 more sources
Diagnosis of platelet-type von Willebrand disease by flow cytometry
Haematologica, 2010 Platelet-type von Willebrand disease (PT-VWD) is a rare autosomal dominant bleeding disorder which is due to a mutation in the gene encoding for platelet glycoprotein Ibα (GPIbα) resulting in enhanced affinity for von Willebrand factor (VWF).
Silvia Giannini +3 more
doaj +2 more sources
Von Willebrand Disease in the elderly: clinical perspectives
Clinical Interventions in Aging, 2018 John Chapin Department of Hematology, Shire, Lexington, MA, USA Abstract: Von Willebrand disease (VWD) is an inherited bleeding disorder that affects up to 1% of the population. In most cases, VWD results from a mutation in the von Willebrand Factor (VWF)
Chapin J
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Mechanical Forces Impacting Cleavage of Von Willebrand Factor in Laminar and Turbulent Blood Flow
Fluids, 2021 Von Willebrand factor (VWF) is a large multimeric hemostatic protein. VWF is critical in arresting platelets in regions of high shear stress found in blood circulation. Excessive cleavage of VWF that leads to reduced VWF multimer size in plasma can cause
Alireza Sharifi, David Bark
doaj +2 more sources
Romanian Journal of Laboratory Medicine, 2016 Acquired von Willebrand disease (AvWD) represents a rare, potentially severe and most likely underdiagnosed category of hemorrhagic syndromes determined by quantitative, qualitative or functional, nonhereditary, alterations of von Willebrand factor (vWF)
Colită Andrei +6 more
doaj +3 more sources
Research and Practice in Thrombosis and Haemostasis, 2020 Von Willebrand disease (VWD) is a bleeding disorder caused by qualitative or quantitative defects of von Willebrand factor (VWF). This case report of a patient with systemic sclerosis and gastrointestinal bleeding from angiodysplasias seeks to address ...
Peter Korsten +2 more
doaj +2 more sources