Pathogen‐reduced cryoprecipitate: Early experiences and inventory management
Transfusion, EarlyView.Abstract Background Room temperature storage of cryoprecipitated antihemophilic factor (CryoAHF) is limited to 6 h. Consequently, this product is stored frozen until requested, necessitating thawing and delaying fibrinogen supplementation. The FDA has approved the use of pathogen‐reduced cryoprecipitated fibrinogen complex (PRCFC), which may be stored ...
C. B. Webb +6 more
wiley +1 more source
Molecular studies of von Willebrand disease: reduced von Willebrand factor biosynthesis, storage, and release in endothelial cells derived from patients with type I von Willebrand disease [published erratum appears in Blood 1990 Nov 1;76(9):1901] [PDF]
, 1990 Bruce M. Ewenstein +3 more
openalex +1 more source
An experimental comparison and user evaluation of three different dried plasma products
Vox Sanguinis, EarlyView.Abstract Background and Objectives Access to blood components in pre‐hospital bleeding resuscitation is challenging. Dried plasma is a logistically superior alternative, and new products are emerging. Therefore, we aimed to evaluate laboratory and practical differences in three differently produced dried plasma products.
Kristina Ehn +5 more
wiley +1 more source
CLINICAL CONTRIBUTION TO VON WILLEBRAND DISEASE IN CHILDREN AFFECTED BY PATHOLOGIES WITH ENDOTHELIAL DAMAGE IN PRESENCE OF BLEEDING MANIFESTATIONS 187 [PDF]
, 1997 N Violante +6 more
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Women in space: A review of known physiological adaptations and health perspectives
Experimental Physiology, EarlyView.Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Environmental modulators of vascular physiology and inflammation
Experimental Physiology, EarlyView.Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne +3 more
wiley +1 more source
Identification of two mutations (Arg611Cys and Arg611His) in the A1 loop of von Willebrand factor (vWF) responsible for type 2 von Willebrand disease with decreased platelet-dependent function of vWF [see comments] [PDF]
, 1995 Lysiane Hilbert +2 more
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The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic +9 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, Volume 39, Issue 18, 30 September 2025.ABSTRACT Desmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics.
Sophie Hodin +7 more
wiley +1 more source