Results 81 to 90 of about 192,512 (365)
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Myeloproliferative neoplasms (MPN) are associated with an increased cardiovascular risk including acute coronary syndrome. However, there is a lack of comprehensive data regarding the rate of percutaneous coronary intervention (PCI), as well as the in‐hospital characteristics and outcomes for MPN patients.
Song Peng Ang +8 more
wiley +1 more source
Identifying and Predicting Parkinson's Disease Subtypes through Trajectory Clustering via Bipartite Networks [PDF]
, 2019 Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based Trajectory Profile Clustering (TPC) algorithm for 1) identification of PD subtypes and 2) early prediction of ...
arxiv +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel +11 more
wiley +1 more source
Spatial von-Mises Fisher Regression for Directional Data [PDF]
arXiv, 2022 Spatially varying directional data are routinely observed in several modern applications such as meteorology, biology, geophysics, engineering, etc. However, only a few approaches are available for covariate-dependent statistical analysis for such data.
arxiv
Von Willebrand Disease in the elderly: clinical perspectives
Clinical Interventions in Aging, 2018 John Chapin Department of Hematology, Shire, Lexington, MA, USA Abstract: Von Willebrand disease (VWD) is an inherited bleeding disorder that affects up to 1% of the population. In most cases, VWD results from a mutation in the von Willebrand Factor (VWF)
Chapin J
doaj
Endothelial dysfunction in the cardiovascular disease puzzle [PDF]
Medicinski Glasnik, 2009 Endothelial dysfunction (ED) is a syndrome characterized by impairment of endothelium dependent vasodilatation,altered anticoagulant, anti-inflammatory and vascular remodeling properties.
Melanija Ražov Radas +5 more
doaj
Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]
, 2017 NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina +8 more
core +1 more source
Prophylaxis in von Willebrand disease [PDF]
Annals of Hematology, 2007 Von Willebrand disease (VWD), the most common hereditary bleeding disorder, is divided into three types depending on the quantitative (type 1 and 3) or qualitative (type 2) abnormality of von Willebrand factor (VWF). About 70-80% of VWD patients can be treated with the synthetic product desmopressin, while the others necessitate factor VIII/VWF ...
Giuseppe Lippi +2 more
openaire +4 more sources
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
Prenatal Sugar Consumption and Late-Life Human Capital and Health: Analyses Based on Postwar Rationing and Polygenic Scores [PDF]
arXiv, 2023 Maternal sugar consumption in utero may have a variety of effects on offspring. We exploit the abolishment of the rationing of sweet confectionery in the UK on April 24, 1949, and its subsequent reintroduction some months later, in an era of otherwise uninterrupted rationing of confectionery (1942-1953), sugar (1940-1953) and many other foods, and we ...
arxiv