Results 81 to 90 of about 58,549 (319)

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]

, 2018
Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Bartolomeo S., Di Benedetto P., Giacomelli R., Guggino G., Liakouli V., Panzera N., Ruscitti P., Triolo G.   +11 more
core   +1 more source

Elevating and empowering reproductive futures: Pediatric and adolescent gynecology's specialized care across the globe

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pediatric and adolescent gynecology (PAG) is an expanding subspecialty of obstetrics and gynecology that addresses the reproductive health needs of girls and young women worldwide. In regions with limited subspecialist healthcare providers, general obstetricians, gynecologists, and nurse‐midwives, frontline healthcare providers provide ...
Nichole A. Tyson, Méabh Ní Bhuinneáin, Hema Divakar, Lauren Mauger, Judith Simms Cendan, Marisa Labovsky, FIGO Committee on Adolescent and Youth Health   +6 more
wiley   +1 more source

FIGO good practice recommendations: Assisted vaginal birth and the second stage of labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Cesarean birth (CB) rates are increasing globally, with a current prevalence of 21.1% and a projected prevalence of 28.5% by 2030. Conversely, assisted vaginal birth (AVB) rates are declining, with reported rates of less than 10% in low‐ and middle‐income countries (LMICs) and 10%–15% in high‐income countries (HICs). In some African countries,
Akaninyene E. Ubom, Eytan R. Barnea, Nicoletta DiSimone, Martin Mueller, Jolly Beyeza‐Kashesya, Ines Nunes, Albaro J. Nieto‐Calvache, Elif G. Topcu, Zechariah J. Malel, Bo Jacobsson, Alison Wright, the FIGO Childbirth and Postpartum Hemorrhage Committee   +11 more
wiley   +1 more source

Soluble C5b‐9 (sC5b‐9) in Pediatrics—A Clinical Assessment

Journal of Clinical Laboratory Analysis, EarlyView.
The sc5b9 assay is a simple laboratory‐developed test that can be used in specific patients to monitor the course of disease, severity, or response to therapy. Future studies using this assay, which show excellent adaptability to a clinical laboratory, will reveal the multiple uses of testing for complement activation.
Ridwan B. Ibrahim, Radwa Almamoun, Sarah E. Sartain, Sridevi Devaraj   +3 more
wiley   +1 more source

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]

, 2016
OBJECTIVE: To examine whether lung endothelial cells (ECs) from patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) express mesenchymal cell-specific proteins and gene transcripts, indicative of the occurrence of endothelial-
Arciniegas, Beon, Cooley, Del Galdo, Falke, Gabrielli, Gilbane, Good, Goumans, Hashimoto, Herzog, Herzog, Hinz, Hinz, Humphreys, Jimenez, Katsumoto, Kendall, Kramann, Lamouille, LeBleu, Li, Li, Marelli-Berg, Matucci-Cerinic, McAnulty, Medici, Meeteren, Nolan, Pattanaik, Piera-Velazquez, Piera-Velazquez, Poslethwaite, Ranchoux, Rieder, Strieter, Varga, Veraldi, Wells, Yoshimatsu, Zeisberg, Zeisberg   +41 more
core   +2 more sources

An incidental finding of mesenteric hematoma in a patient with a new diagnosis of inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Mesenteric hematomas (MHs) are relatively rare and are characterized by localized bleeding in the mesenteric vascular tree presenting with abdominal pain, vomiting, abdominal distension, masses, and hypotension. We report a case of a MH which was incidentally found in a 10‐year‐old patient with a new diagnosis of ulcerative colitis (UC).
Breanna Brown, Anna Hunter, Kimberly Trieschmann   +2 more
wiley   +1 more source

Еndothelial dysfunction due to sodium nitrite

Journal of Education, Health and Sport, 2020
In the report of the World Health Organization from 1990 to 2016 to this day, Ukraine continues to occupy first place in the European region in morbidity and mortality from diseases of the cardiovascular system. One of the predictors and key links in the
I. V. Savitsky, G. V. Kryukovа, I. V. Myastkivska, T. V. Gerasymenko   +3 more
doaj   +1 more source

Substrate‐Dependent Variability in Viability and Angiogenic Marker Expression Among Three Endothelial Cell Subtypes: Insights for Artificial Tissue Vascularization

Macromolecular Bioscience, EarlyView.
The study investigates how four ECM‐mimicking biomaterials—fibrin, fibronectin, and non‐crosslinked or crosslinked gelatin—affect different types of human endothelial cells. Cell viability, morphology, and angiogenic marker expression are evaluated. Results reveal substrate‐dependent effects on cell behavior and emphasize the importance of selecting ...
Jernej Vajda, Boštjan Vihar, Marko Milojević, Dragana Bjelić, Amadeja Brečko, Uroš Maver   +5 more
wiley   +1 more source

Acquired von Willebrand disease associated with smoldering multiple myeloma and hereditary hemorrhagic telangiectasia successfully treated with daratumumab, pomalidomide, and dexamethasone: hitting three birds with one stone? – case report

Frontiers in Hematology
Acquired von Willebrand disease (AvWD) is a rare bleeding disorder that results from a structural or functional defect of von Willebrand factor.
Lemchukwu Amaeshi, Jacqueline N. Poston, Jacqueline N. Poston, Mansour Gergi   +3 more
doaj   +1 more source

COMBINATION OF THE ULCERATIVE COLITIS AND VON WILLEBRAND DISEASE (A CASE REPORT)

Архивъ внутренней медицины, 2017
In the article the clinical observation of a rare combination of ulcerative colitis with von Willebrand’s disease in 33-year-old patient. Comorbidity require specific types of the disease, taking into account the peculiarities of its course, monitoring ...
I. A. Grishechkina, T. V. Polomoshnova
doaj   +1 more source