Results 81 to 90 of about 55,967 (276)

Human plasma-derived FVIII/VWD concentrate (Biostate): a review of experimental and clinical pharmacokinetic, efficacy and safety data

Drugs in Context, 2016
Human plasma-derived factor VIII/von Willebrand factor complex concentrates are used to control bleeding in patients with von Willebrand disease (VWD) or haemophilia A (HA).
Paul Harper, Emmanuel J Favaloro, Julie Curtin, Chris Barnes, Scott Dunkley   +4 more
doaj   +1 more source

Plasma Level of von Willebrand Factor Propeptide at Diagnosis: A Marker of Subsequent Renal Dysfunction in Autoimmune Rheumatic Diseases

Clinical and Applied Thrombosis/Hemostasis, 2020
Introduction: Patients with systemic autoimmune rheumatic diseases (SARDs) such as rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren syndrome, and systemic sclerosis, which are chronic inflammatory diseases, are prone to develop renal ...
Noritaka Yada, Kiyomi Yoshimoto, Hiromasa Kawashima, Ryo Yoneima, Nobushiro Nishimura, Yoshiaki Tai, Emiko Tsushima, Makiko Miyamoto, Shiro Ono, Masanori Matsumoto, Takashi Fujimoto, Kenji Nishio   +11 more
doaj   +1 more source

Potential Role of Ultrafine Particles in Associations between Airborne Particle Mass and Cardiovascular Health [PDF]

, 2005
Numerous epidemiologic time-series studies have shown generally consistent associations of cardiovascular hospital admissions and mortality with outdoor air pollution, particularly mass concentrations of particulate matter (PM) ≤2.5 or ≤10 μm in diameter
Constantinos Sioutas, Desai MM, Diaz-Sanchez D, Godleski JJ, MacNee W, McGrath JJ, Pekkanen J, Ralph J. Delfino, Rifai N, Samet JM, Schreck R, Shaista Malik, Wichmann HE   +12 more
core   +2 more sources

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells [PDF]

, 2016
Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological behavior of cardiac valve substitutes.
Aguiari, Paola, Barbon, Silvia, Bertalot, Thomas, Conconi, MARIA TERESA, DI LIDDO, Rosa, Gandaglia, Alessandro, Gerosa, Gino, Iop, Laura, Mandoli, Amit, Parnigotto, PIER PAOLO, Schrenk, Sandra, Tasso, Alessia   +11 more
core   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Enfermedad de von Willebrand adquirida. Aspectos generales Acquired von Willebrand’s disease. General aspects

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2004
La enfermedad de von Willebrand adquirida es una enfermedad hemorrágica poco común. Aproximadamente en la mitad de los casos se asocia con enfermedades linfoproliferativas y también se ha relacionado con trastornos mieloproliferativos, neoplasias ...
Alina Díaz Concepción
doaj  

Defining von Willebrand disease [PDF]

Blood, 2016
In this issue of Blood, Flood et al report on bleeding symptoms and laboratory analyses in 482 subjects diagnosed with type 1 von Willebrand disease (VWD) as part of the Zimmerman Program, a multicenter study of VWD.1 Their findings provide insight into the underlying DNA variants in VWD, and also raise questions about the diagnosis of VWD and of ...
openaire   +2 more sources

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, EarlyView.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source