Results 1 to 10 of about 109,978 (227)

von Willebrand factor and early diabetic retinopathy: no evidence for a relationship in patients with Type 1 (insulin-dependent) diabetes mellitus and normal urinary albumin excretion [PDF]

, 1992
High plasma levels of von Willebrand factor, an indicator of endothelial cell dysfunction, have been reported in both diabetic retinopathy and nephropathy.
Baarsma, G.S. (Seerp), Donker, A.J.M. (Ab J.), Nauta, J.J.P. (Jos), Ottolander, G.J. (Gerard) den, Polak, B.C.P. (Bettine), Stehouwer, C.D. (Coen), Zellenrath, P. (P.)   +6 more
core   +3 more sources

Homocisteína plasmática total e fator von Willebrand no diabete melito experimental Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus [PDF]

Arquivos Brasileiros de Cardiologia, 2007
OBJETIVOS: Determinar os valores plasmáticos de homocisteína e fator von Willebrand, como marcador de disfunção endotelial, em ratos com diabete melito induzido por estreptozotocina.
Renato Delascio Lopes, Lindalva Batista Neves, Vânia D'Almeida, Gleice Margarete de Souza Conceição, Alexandre Gabriel Junior   +4 more
doaj   +3 more sources

von Willebrand Factor (VWF) Inhibitors in Two Brothers with von Willebrand Disease: A Case Report [PDF]

TH Open
The development of inhibitors to von Willebrand factor (VWF) is a rare but potentially serious complication of VWF replacement therapy in patients with von Willebrand disease (VWD).
Claudia Djambas Khayat, Anna Pavlova, Sylvia Werner, Sigurd Knaub, Robert F. Sidonio   +4 more
doaj   +2 more sources

Von Willebrand factor [PDF]

Clinical Medicine, 2020
Editor – Ladikou et al have elegantly shown in their series that levels of factor VIII and von Willebrand factor (VWF) are markedly raised in patients with COVID-19 and that there is a reduced level of ADAMTS13 which may be secondary to depletion of the enzyme through consumption.[1][1 ...
Bhogal, P, Jensen, M, Hart, D, Makalanda, L, Collins, GB, Spooner, O, Jaffer, O   +6 more
openaire   +5 more sources

The Role of von Willebrand Factor in the Pathogenesis of C3 Glomerulopathy. [PDF]

Kidney Int Rep
Hua Z, Chen Y, Han S, Yu X, Tan Y, Yu F, Chen M, Zhao M.   +7 more
europepmc   +2 more sources

A novel approach to laboratory assessment and reporting of platelet von Willebrand factor

Platelets, 2022
The interaction of platelets with von Willebrand factor is essential for primary hemostasis. Concentration and activity of plasma von Willebrand factor are routine parameters in the assessment of hemostasis disorders. In addition to plasma von Willebrand
Thorsten Kragh, Isabell Pekrul, Helmut W. Ott, Michael Spannagl, Patrick Möhnle   +4 more
doaj   +1 more source

Zebrafish von Willebrand factor [PDF]

Blood Cells, Molecules, and Diseases, 2010
von Willebrand factor (vWF) is a large protein involved in primary hemostasis. A dysfunction in this protein or an insufficient production of the protein leads to improper platelet adhesion/aggregation, resulting in a bleeding phenotype known as von Willebrand disease (vWD).
Maira, Carrillo, Seongcheol, Kim, Surendra Kumar, Rajpurohit, Vrinda, Kulkarni, Pudur, Jagadeeswaran   +4 more
openaire   +2 more sources

Cryptic non-canonical splice site activation is part of the mechanism that abolishes multimer organization in the c.2269_2270del von Willebrand factor

Haematologica, 2020
We report a new pathogenic mechanism in von Willebrand disease involving the use of a non-canonical splicing site. The proband, carrying the homozygous c.2269_2270del mutation previously classified as a type 3 mutation, showed severely reduced plasma and
Viviana Daidone, Eva Galletta, Luigi De Marco, Alessandra Casonato   +3 more
doaj   +1 more source

Evaluation of a new semi-automated Hydragel 11 von Willebrand factor multimers assay kit for routine use [PDF]

Journal of Medical Biochemistry, 2021
Background: Accurate diagnosis and classification of von Willebrand disease (VWD) are essential for optimal management. The von Willebrand factor multimers analysis (VWF:MM) is an integral part of the diagnostic process in the phenotypic classification ...
Pikta Marika, Szanto Timea, Viigimaa Margus, Lejniece Sandra, Balode Dārta, Saks Kadri, Banys Valdas   +6 more
doaj   +1 more source

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor. [PDF]

PLoS ONE, 2017
Adhesion of erythrocytes to endothelial cells lining the vascular wall can cause vaso-occlusive events that impair blood flow which in turn may result in ischemia and tissue damage.
Michel W J Smeets, Ruben Bierings, Henriet Meems, Frederik P J Mul, Dirk Geerts, Alexander P J Vlaar, Jan Voorberg, Peter L Hordijk   +7 more
doaj   +1 more source