Results 101 to 110 of about 212,775 (379)
Mediterranean Journal of Hematology and Infectious Diseases, 2020 Aim : Type 3 von Willebrand disease (VWD) is the most severe form of VWD, characterized by a near-total absence of von Willebrand factor (vWF) leading to a huge deficiency in plasmatic factor VIII (FVIII). VWD may be confused with hemophilia A, sometimes
Adia Eusèbe Adjambri +7 more
doaj +1 more source
Behaviour of the von Willebrand Factor in Blood Flow [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +3 more
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Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Cardiovascular therapeutic devices typically require systemic heparin due to underlying thrombotic risk. The Impella axial flow system further relies on internal perfusion with either a heparin‐containing or sodium bicarbonate purge solution during operation.
Kaitlyn R. Ammann +7 more
wiley +1 more source
ADAMTS‐13 and von Willebrand factor: a dynamic duo
Journal of Thrombosis and Haemostasis, 2017 von Willebrand factor (VWF) is a key player in hemostasis, acting as a carrier for factor VIII and capturing platelets at sites of vascular damage.
K. South, D. Lane
semanticscholar +1 more source
Characterization of the defect of the factor VIII/von Willebrand factor protein in von Willebrand's disease [PDF]
Blood, 1982 Abstract The factor VIII/von Willebrand factor (f.VIII/vWf) protein was purified from the plasma of a patient with von Willebrand's disease (vWd). The patient had all of the classic laboratory findings of vWd except for the ristocetin-induced platelet aggregation of his own platelet-rich plasma.
Mary C. Cregger +2 more
openaire +3 more sources
A perfect storm : polycystic ovary syndrome masking underlying yype 1 Von Willebrand disease [PDF]
, 2016 Von Willebrand Disease (vWD) is the most common inherited bleeding diathesis worldwide and results in defects in von Willebrand Factor (vWF), inducing a hypocoagulable state.
Coberly, Emily +3 more
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Clinical Pharmacology &Therapeutics, EarlyView.Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel +11 more
wiley +1 more source
Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease. [PDF]
PLoS ONE, 2016 Von Willebrand disease (VWD) may be caused by an impaired von Willebrand factor (VWF) synthesis, its increased clearance or abnormal function, or combinations of these factors.
Alessandra Casonato +5 more
doaj +1 more source
von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends.
Blood, 2015 To understand the placement of a certain protein in a physiological system and the pathogenesis of related disorders, it is not only of interest to determine its function but also important to describe the sequential steps in its life cycle, from ...
P. Lenting, O. Christophe, C. Denis
semanticscholar +1 more source
Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex. [PDF]
Journal of Clinical Investigation, 1985 von Willebrand antigen II (vW AgII) and von Willebrand factor (vWf) are immunochemically distinct proteins that are deficient in the plasma and platelets of patients with severe von Willebrand's disease. Normal human umbilical vein endothelial cells were cultured in the presence of [35S]methionine.
E G Levin +2 more
openaire +3 more sources