Results 111 to 120 of about 212,775 (379)
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia+2 more
wiley +1 more source
Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.
UNLABELLED Circulating factor VIII (FVIII) is derived from liver and from extrahepatic sources probably of endothelial origin, but the vascular sites of FVIII production remain unclear.
Junliang Pan+12 more
semanticscholar +1 more source
Evaluation of ELISA procedures to detect von Willebrand Factor with monoclonal antibodies [PDF]
The von Willebrand Factor is a multimeric glycoprotein responsible for the promotion of platelet adhesion and aggregation at sites of vascular injury, and for FVIII stabilization.
Bandinelli, Eliane+5 more
core +1 more source
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely+14 more
wiley +1 more source
Von Willebrand Disease in the Netherlands [PDF]
Von Willebrand Disease (VWD) is the most common inherited bleeding disorder resulting in mucocutaneous bleeding, like epistaxis, oral cavity bleeding and menorrhagia. VWD is caused by reduced or dysfunctional von Willebrand Factor (VWF).
Sanders, Y.V. (Yvonne)
core
Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D.+9 more
core +2 more sources
ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.
Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on ...
X. Zheng
semanticscholar +1 more source
Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
core +1 more source
Heart failure (HF) with supranormal ejection fraction (HFsnEF) is an unnoticed but emerging entity in HF. This study showed that HFsnEF carries a similarly increased cardiovascular risk as HF with reduced ejection fraction (HFrEF) and distinct structural and proteomic characteristics from HFrEF, warranting a further comprehensive understanding and ...
Yasuhiko Sakata+19 more
wiley +1 more source
Relation of morning serum cortisol to prothrombotic activity in women with stable coronary artery disease [PDF]
Background: Increased circulating cortisol levels have been associated with severity of atherosclerosis. Low-grade systemic thrombogenicity plays a major role in the initiation and progression of coronary disease.
Kudielka, Brigitte+3 more
core