Results 121 to 130 of about 212,775 (379)

Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report

Caspian Journal of Neurological Sciences, 2022
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani, Shirin Haghighat, Maryam Poursadeghfard   +2 more
doaj  

Hemostatic efficacy, safety, and pharmacokinetics of a recombinant von Willebrand factor in severe von Willebrand disease.

Blood, 2015
This phase 3 trial evaluated the safety and hemostatic efficacy of a recombinant von Willebrand factor (rVWF) for treatment of bleeds in severe von Willebrand disease (VWD).
J. Gill, G. Castaman, J. Windyga, P. Kouides, M. Ragni, F. Leebeek, Ortrun Obermann-Slupetzky, M. Chapman, S. Fritsch, B. Pavlova, I. Presch, B. Ewenstein   +11 more
semanticscholar   +1 more source

The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis. [PDF]

, 2017
We recently found that integrin αvβ3 binds to fibroblast growth factor (FGF)-αvβ31 (FGF1), and that the integrin-binding defective FGF1 mutant (Arg-50 to glutamic acid, R50E) is defective in signalling and antagonistic to FGF1 signalling. R50E suppressed
Hamada, Yoshinosuke, Hatori, Nobuaki, Kawaguchi, Naomasa, Lam, Kit S, Matsuura, Nariaki, Mori, Seiji, Shih, Tsung-Chieh, Takada, Yoko K, Takada, Yoshikazu, Wu, Chun-Yi, Yamamoto, Hirofumi   +10 more
core   +2 more sources

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri, Yelena Fruchou, Caroline Brodbeck, Marianne Bastien, Amandine Lioux, Giulia Gouy, Marion Cortet, Gil Dubernard, Yesim Dargaud   +8 more
wiley   +1 more source

Endothelial dysfunction and inflammation in asymptomatic proteinuria [PDF]

, 2003
Background. Proteinuria is associated with vascular risk and a systemic increase in vascular permeability. Endothelial dysfunction occurs early in atherosclerosis and modulates vascular permeability. Vascular risk and chronic inflammation are associated.
Adams, Adams, Biasucci, Blum, Casino, Celermajer, Chauveau, Clausen, Cleland, Cooke, Dietz, Doshi, Drab, Festa, Fichtlscherer, Furchgott, Fuster, Grossmann, Haaber, Haverkate, Hernandez, Jensen, Jensen, Johnston, Joles, Kannel, Khan, Khan, Koenig, Kubes, Laurent, Lewis, Lewis, Lip, Liuzzo, Ludmer, Luscher, Michel, Mogensen, Moncada, Morris, Morris, Morrow, Nabel, Noon, Noon, Pohl, Quyyumi, Rayman, Razani, Ridker, Ross, Ross, Rubanyi, Schalkwijk, Schubert, Serne, Shore, Sorensen, Stroes, Tenland, Thambyrajah, Tooke, van Guldener, Vogel, Williams, Yuan, Yudkin   +67 more
core   +1 more source

Evaluation of Function and Biochemical Parameters of Platelet Concentrates (PCs) Prepared From Blood Donors With a History of COVID‐19 During the Platelet Storage

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background COVID‐19 can affect hematological and biochemical parameters, potentially altering platelet function. This study aimed to evaluate the long‐term effects of COVID‐19 on the quality of platelet concentrates (PCs) collected from donors with a history of infection.
Fatemeh Arastehnazar, Mohammad Hessam Rafiee, Mohammad Reza Deyhim, Faezeh Ghasemi, Amir Teimourpour   +4 more
wiley   +1 more source

Von Willebrand's disease: case report and review of literature

The Pan African Medical Journal, 2017
Von Willebrand Disease (VWD) is the most common human inherited bleeding disorder due to a defect of Von Willebrand Factor (VWF), which a glycoprotein crucial for platelet adhesion to the subendothelium after vascular injury.
Hanae Echahdi, Brahim El Hasbaoui, Mohamed El Khorassani, Aomar Agadr, Mohamed Khattab   +4 more
doaj   +1 more source

Natural progression and prediction markers in non‐clinically significant oesophageal varices in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Limited literature exists on non‐clinically significant varices (nCSV) and progression in children with portal hypertension (PHT). This study investigates trends and associations in this cohort. Methods This retrospective cohort study analysed 70 children with nCSV undergoing surveillance endoscopy between January 2012 and 2024 ...
Cody Chan, Akshat Goel, Robert Hegarty, Bethany Tucker, Vandana Jain, Eirini Kyrana, Tassos Grammatikopoulos   +6 more
wiley   +1 more source

Postpartum von Willebrand factor levels in women with and without von Willebrand disease and implications for prophylaxis

Haemophilia, 2015
The aim of this study was to elucidate the fall in von Willebrand factor (VWF) and factor VIII activity (FVIII) after childbirth in women with and without von Willebrand disease (VWD).
A. James, B. Konkle, B. Konkle, P. Kouides, M. Ragni, Betty Thames, Sweta Gupta, S. Sood, S. K. Fletcher, C. Philipp   +9 more
semanticscholar   +1 more source

An incidental finding of mesenteric hematoma in a patient with a new diagnosis of inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Mesenteric hematomas (MHs) are relatively rare and are characterized by localized bleeding in the mesenteric vascular tree presenting with abdominal pain, vomiting, abdominal distension, masses, and hypotension. We report a case of a MH which was incidentally found in a 10‐year‐old patient with a new diagnosis of ulcerative colitis (UC).
Breanna Brown, Anna Hunter, Kimberly Trieschmann   +2 more
wiley   +1 more source