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Intraindividual variability of von Willebrand factor and the need for repeated testing. [PDF]

open access: yesRes Pract Thromb Haemost
Kirkeby MH   +3 more
europepmc   +1 more source

Recombinant von Willebrand Factor (vonicog alfa) reduces platelet inhibition caused by antiplatelet drugs and has potential as an acute haemostatic agent. [PDF]

open access: yesHaematologica
Desborough MJR   +9 more
europepmc   +1 more source
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von Willebrand disease and von Willebrand factor

Haemophilia, 2022
AbstractSummaryProgress in both basic and translational research into the molecular mechanisms of VWD can be seen in multiple fields.Genetics of VWDIn the past several decades, knowledge of the underlying pathogenesis of von Willebrand disease (VWD) has increased tremendously, thanks in no small part to detailed genetic mapping of the von Willebrand ...
Brooke, Sadler   +2 more
openaire   +2 more sources

von Willebrand factor

The FASEB Journal, 1993
von Willebrand factor is a multimeric glycoprotein essential for the normal arrest of bleeding after tissue injury (hemostasis). The molecule is present in blood, both in plasma and inside platelets, as well as in endothelial cells and the subendothelial matrix of the vessel wall. Through multiple functional domains, von Willebrand
Z M, Ruggeri, J, Ware
openaire   +2 more sources

The von Willebrand factor

La Ricerca in Clinica e in Laboratorio, 1990
Von Willebrand factor (vWf) is a multimeric and multivalent adhesive protein which is essential for platelet adhesion to subendothelium and for stabilization of factor VIII procoagulant activity in circulation. The quantitative measurement of vWf involves essentially two different approaches.
F, Rodeghiero, G, Castaman
openaire   +2 more sources

Von Willebrand factor and thrombosis

Annals of Hematology, 2006
There is increasing evidence that von Willebrand factor (VWF), an adhesive multimeric protein that has an important function in primary hemostasis and as a carrier of factor VIII, has a pivotal role in thrombogenesis. In fact, while the presence in plasma of unusually large VWF multimers due to a congenital or acquired deficiency of a VWF-cleaving ...
Franchini M, LIPPI, Giuseppe
openaire   +2 more sources

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