Results 161 to 170 of about 52,208 (254)

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Von Willebrand Factor as a Therapeutic Target in Thrombotic Disorders. [PDF]

Thromb Haemost
Jongejan YK, van Vlijmen BJM, Eikenboom JCJ.   +2 more
europepmc   +1 more source

The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models

Photochemistry and Photobiology, EarlyView.
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva, Rebeca Barros Nascimento, Giovanna Lopes Carvalho, Rebeca Boltes Cecatto, Maria Stella Moreira, Maria Fernanda Setúbal Destro Rodrigues   +5 more
wiley   +1 more source

von Willebrand Factor Deficiency Inhibits Endothelial-to-Mesenchymal Transition to Attenuate Pulmonary Fibrosis. [PDF]

Am J Respir Cell Mol Biol
Wang W, Chen S, Xi Z, Si Y, Liu Y, Chen J, Wang B, Zhu D, Gong L.   +8 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Association between neutrophil extracellular traps, the Von Willebrand factor axis, and clinical outcome in stable coronary artery disease. [PDF]

Front Cardiovasc Med
Bratseth V, Kindberg KM, Warlo EMK, Pettersen AR, Opstad TB, Langseth MS, Helseth R, Lunde IG.   +7 more
europepmc   +1 more source

Oral wound healing in the elderly: Mechanisms, challenges, and innovations

Periodontology 2000, EarlyView.
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker, Sandra H. Stuhr, Gustavo Avila‐Ortiz, Andrea Pilloni, Lorenzo Marini, Rogerio Castilho, Beth I. Wallace, Yvonne L. Hernandez‐Kapila   +7 more
wiley   +1 more source

DNA methylation is associated with von Willebrand factor and coagulation factor VIII plasma levels: the atherosclerosis risk in communities study. [PDF]

Clin Epigenetics
Hahn J, Bressler J, Fornage M, Boerwinkle E, Smith NL, Morrison AC, de Vries PS.   +6 more
europepmc   +1 more source

Maternal–fetal platelet alloimmunization: Identification of risk factors for severe neonatal thrombocytopenia

Transfusion, EarlyView.
Abstract Background Feto‐maternal platelet alloimmunization (FNAIT) is a rare condition (1 in 1500 live pregnancies), most commonly diagnosed based on clinical neonatal hemorrhagic manifestations, which can vary in severity. The aim of our study was to identify risk factors for severe fetal/neonatal thrombocytopenia in cases of FNAIT.
Elise Deroubaix, Marie‐Hélène Emektas, Gauthier Alluin, Pascale Renom, Fanny Rodermann, Mélissa Gilbert, Charles Garabedian, Véronique Houfflin‐Debarge   +7 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source