Homocisteína plasmática total e fator von Willebrand no diabete melito experimental Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus [PDF]
Arquivos Brasileiros de Cardiologia, 2007 OBJETIVOS: Determinar os valores plasmáticos de homocisteína e fator von Willebrand, como marcador de disfunção endotelial, em ratos com diabete melito induzido por estreptozotocina.
Renato Delascio Lopes +4 more
doaj +3 more sources
VON WILLEBRAND FACTOR, ANGIODYSPLASIA AND ANGIOGENESIS [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2013 The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes. We recently described a new role for VWF in controlling angiogenesis, which may have significant clinical ...
Randi, AM, Laffan, MA, Starke, RD
openaire +8 more sources
von Willebrand Factor Multimer Formation Contributes to Immunothrombosis in Coronavirus Disease 2019
Critical Care Medicine, 2021 Supplemental Digital Content is available in the text. OBJECTIVES: Prevention and therapy of immunothrombosis remain crucial challenges in the management of coronavirus disease 2019, since the underlying mechanisms are incompletely understood.
A. Doevelaar +14 more
semanticscholar +1 more source
A novel approach to laboratory assessment and reporting of platelet von Willebrand factor
Platelets, 2022 The interaction of platelets with von Willebrand factor is essential for primary hemostasis. Concentration and activity of plasma von Willebrand factor are routine parameters in the assessment of hemostasis disorders. In addition to plasma von Willebrand
Thorsten Kragh +4 more
doaj +1 more source
The relationship between ABO blood group, von Willebrand factor and primary hemostasis.
Blood, 2020 Numerous studies have reported significant associations between ABO blood group and risk for cardiovascular disease. These studies have consistently demonstrated that thrombotic risk is significantly reduced in blood group O individuals.
Soracha E. Ward +2 more
semanticscholar +1 more source
Von Willebrand factor and cancer; metastasis and coagulopathies
Journal of Thrombosis and Haemostasis, 2020 Von Willebrand factor (VWF) is a multimeric procoagulant plasma glycoprotein that mediates platelet adhesion along the endothelium. In addition to its role maintaining normal hemostasis, more recently novel biological functions for VWF have been ...
S. Patmore, S. Dhami, J. O’Sullivan
semanticscholar +1 more source
The ADAMTS13‐von Willebrand factor axis in COVID‐19 patients
Journal of Thrombosis and Haemostasis, 2020 Severe coronavirus disease 2019 (COVID‐19) is characterized by an increased risk of thromboembolic events, with evidence of microthrombosis in the lungs of deceased patients.
I. Mancini +15 more
semanticscholar +1 more source
CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats [PDF]
, 2014 Successful curative treatment of severe pulmonary arterial hypertension with luminal obliteration will require a thorough understanding of the mechanism underlying the development and progression of pulmonary vascular lesions.
Alhussini, Aysar A. +8 more
core +17 more sources
Haematologica, 2020 We report a new pathogenic mechanism in von Willebrand disease involving the use of a non-canonical splicing site. The proband, carrying the homozygous c.2269_2270del mutation previously classified as a type 3 mutation, showed severely reduced plasma and
Viviana Daidone +3 more
doaj +1 more source