Results 281 to 290 of about 212,775 (379)

Prophylaxis in von Willebrand disease with von Willebrand factor concentrate and nonfactor therapies. [PDF]

Res Pract Thromb Haemost
van Kwawegen CB, Leebeek FWG.
europepmc   +1 more source

BMP signalling in colorectal cancer: losing the yin to WNTs yang

The Journal of Pathology, Volume 266, Issue 3, Page 280-291, July 2025.
Abstract Colorectal cancer (CRC) is the third most common form of cancer globally, and arises from the hyperproliferation of epithelial cells in the intestine. The architecture and maintenance of these cells is governed by two major signalling pathways working in a counter‐gradient: the stem cell WNT signalling pathway, and the prodifferentiation bone ...
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Plasma proteomics in patients with von Willebrand disease and hemophilia A highlights von Willebrand factor as main determinant of response to desmopressin treatment. [PDF]

Res Pract Thromb Haemost
Alferez JDC, Smit ER, Meijer AB, Fijnvandraat K, Kruip MJHA, van Duijl TT, van den Biggelaar M.   +6 more
europepmc   +1 more source

Target‐Mediated Drug Disposition (TMDD) Revisited: High Versus Low‐Affinity Approximations of the TMDD Model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 7, Page 1262-1272, July 2025.
ABSTRACT Target‐mediated drug disposition (TMDD) is often associated with high‐affinity binding to a target resulting in nonlinear pharmacokinetics. For large molecules, such as monoclonal antibodies, this can lead to increased clearance at sub‐saturating concentrations.
Ronny Straube
wiley   +1 more source

Dynamics of a von Willebrand Factor A1 Autoinhibitory Module with O-Linked Glycans and Its Roles in Regulation of GPIbα Binding. [PDF]

J Phys Chem B
Cao Y, Zhang XF, Im W.
europepmc   +1 more source

Silencing of the von Willebrand factor gene in proatherothrombotic <i>APOE∗3-Leiden.CETP</i> transgenic mice. [PDF]

Res Pract Thromb Haemost
Jongejan YK, Dirven RJ, Schrader Echeverri E, de Jong AJL, Pronk ACM, Kooijman S, Rensen PCN, Dahlman JE, Eikenboom JCJ, van Vlijmen BJM.   +9 more
europepmc   +1 more source

Factor VIII/von willebrand factor (FVIII/vWF) in a new intermediate factor VIII concentrate, RCG-5 Japan Red Cross.

, 1985
Akira Yoshioka, Masato Nishino, Midori Shima, Noboru Yoshikawa, Motoshi Yasui, Hiromu Fukui   +5 more
openalex   +2 more sources

Frog‐Derived Neuroregenerative‐Peptide‐Reinforced Bioactive Hydrogels with Injectability, Thermosensitivity, and Enhanced Neurotrophic Function for Repairing Central Nervous Injuries

Small Structures, Volume 6, Issue 7, July 2025.
Herein, the reinforcement of bioactive hydrogels with frog‐derived neuroregenerative peptide (FRNP) is presented to create multifunctional materials with injectability, thermosensitivity, and neurorepair capabilities. The formation of a porous, dual‐network hydrogel structure, combined with the action of FRNP, promotes the proliferation, migration, and
Zhengang Sun, Zhenjuan Sun, Chenxi Du, Hongyu Chen, Xingchao Zhang, Yuanyuan Liu, Fang Dong, Xuexiao Ma, Gang Wei, Haiyuan Yue   +9 more
wiley   +1 more source

Isolation and characterization of a collagen binding domain in human von Willebrand factor.

, 1986
F. I. Pareti, Yoshihiro Fujimura, Judith Dent, Linda Z. Holland, T S Zimmerman, Z M Ruggeri   +5 more
openalex   +1 more source