Results 31 to 40 of about 214,027 (378)

The influence of protein adsorption on interactions of cultured human endothelial cells with polymers [PDF]

, 1987
A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of small-diameter vascular grafts.
Aken, W.G. van, Bantjes, A., Beugeling, T., Detmers, J.P., Feijen, J., Vreriks, C.M., Wachem, P.B. van   +6 more
core   +9 more sources

VWF/ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma

BMC Gastroenterology, 2019
Background To investigate the von Willebrand factor to ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma (HCC) in cirrhosis.
Hiroaki Takaya, Tadashi Namisaki, Mitsuteru Kitade, Kosuke Kaji, Keisuke Nakanishi, Yuki Tsuji, Naotaka Shimozato, Kei Moriya, Kenichiro Seki, Yasuhiko Sawada, Soichiro Saikawa, Shinya Sato, Hideto Kawaratani, Takemi Akahane, Ryuichi Noguchi, Masanori Matsumoto, Hitoshi Yoshiji   +16 more
doaj   +1 more source

Inflammation, von Willebrand factor, and ADAMTS13.

Blood, 2018
Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF, assembly of hyperadhesive VWF strings and fibers, cleavage by ADAMTS13, and ...
Junmei Chen, D. Chung
semanticscholar   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Cervenak, László, Förhécz, Zsolt, Gombos, Tímea, Hársfalvi, Jolán, Jánoskuti, Lívia, Kunde, Jan, Makó, Veronika, Papassotiriou, Jana, Pozsonyi, Zoltán, Prohászka, Zoltán   +10 more
core   +1 more source

ON THE VERSATILITY OF VON WILLEBRAND FACTOR

Mediterranean Journal of Hematology and Infectious Diseases, 2013
Von Willebrand factor (VWF) is a large multimeric protein, the function of which has been demonstrated to be pivotal to the haemostatic system. Indeed, quantitative and/or qualitative abnormalities of VWF are associated with the bleeding disorder Von Willebrand disease (VWD).
Rauch, Antoine, Wohner, Nikolett, Christophe, Olivier D., Denis, Cécile V., Susen, Sophie, Lenting, Peter J.   +5 more
openaire   +4 more sources

Hemostatic factors and risk of coronary heart disease in general populations: new prospective study and updated meta-analyses [PDF]

, 2013
<p>Background: Activation of blood coagulation and fibrinolysis may be associated with increased risk of coronary heart disease. We aimed to assess associations of circulating tissue plasminogen activator (t-PA) antigen, D-dimer and von Willebrand ...
Aspelund, T., Di Angelantonio, E., Eiriksdottir, G., Gudnason, V., Lowe, G., Rumley, A., Thompson, A., Willeit, P.   +7 more
core   +6 more sources

von Willebrand factor regulation of blood vessel formation.

Blood, 2018
Several important physiological processes, from permeability to inflammation to hemostasis, take place at the vessel wall and are regulated by endothelial cells (ECs). Thus, proteins that have been identified as regulators of one process are increasingly
A. Randi, Koval E Smith, G. Castaman
semanticscholar   +1 more source

Von Willebrand Disease [PDF]

, 2017
Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
core   +2 more sources

Pregnancy and delivery in women with von Willebrand’s disease and different von Willebrand factor mutations

Haematologica, 2010
Background Pregnancy in von Willebrand’s disease may carry a significant risk of bleeding. Information on changes in factor VIII and von Willebrand factor and pregnancy outcome in relation to von Willebrand factor gene mutations are very scanty.Design ...
Giancarlo Castaman, Alberto Tosetto, Francesco Rodeghiero   +2 more
doaj   +1 more source

Insights into pathological mechanisms of missense mutations in C-terminal domains of von Willebrand factor causing qualitative or quantitative von Willebrand disease

Haematologica, 2013
The carboxyl-terminal domains of von Willebrand factor, D4-CK, are cysteine-rich implying that they are structurally important. In this study we characterized the impact of five cysteine missense mutations residing in D4-CK domains on the conformation ...
Hamideh Yadegari, Julia Driesen, Anna Pavlova, Arijit Biswas, Vytautas Ivaskevicius, Robert Klamroth, Johannes Oldenburg   +6 more
doaj   +1 more source