Results 31 to 40 of about 109,978 (227)

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]

open access: yes, 2009
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Bõze, Tamás   +9 more
core   +1 more source

Recombinant von Willebrand Factor for Pediatric Patient with von Willebrand Disease: First Report in Korea

open access: yesClinical Pediatric Hematology-Oncology, 2021
von Willebrand disease (VWD) is the most common hereditary bleeding disorder. The treatment of VWD consists mainly of desmopressin and plasma-derived von Willebrand factor (pd-VWF) concentrate.
Seoin Kim, Young Shil Park
doaj   +1 more source

Desmopressin in moderate hemophilia a patients: A treatment worth considering [PDF]

open access: yes, 2018
Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed.
Beckers, E.   +12 more
core   +4 more sources

Von Willebrand factor, angiodysplasia and angiogenesis [PDF]

open access: yes, 2013
The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes.
Laffan, MA, Randi, AM, Starke, RD
core   +2 more sources

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking

open access: yesHaematologica, 2017
Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood ...
Eduard H.T.M. Ebberink   +7 more
doaj   +1 more source

Establishing reference intervals for von Willebrand factor multimers [PDF]

open access: yesJournal of Medical Biochemistry, 2022
Background: von Willebrand factor (VWF) multimers (VWF:MM) methodologies are technically difficult, laborious, time consuming, non-standardized and results vary between laboratories. A new semi automated VWF:MM assay is available for routine use (Sebia).
Pikta Marika   +9 more
doaj   +1 more source

The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study [PDF]

open access: yesZanco Journal of Medical Sciences, 2018
Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or ...
Sazgar Anwar Hameed, Salar Adnan Ahmed
doaj   +1 more source

Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]

open access: yes, 2014
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
core   +1 more source

High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]

open access: yes, 2015
Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono)   +3 more
core   +2 more sources

Factor fon Willebrand antigen in endothelium functional state assessment in patients with systemic lupus erythematosus

open access: yesНаучно-практическая ревматология, 2004
Objective. To determine the importance of von Willebrand factor antigen as marker of endotheliae damage at the patients with systemic lupus erythematosus (SLE). Material and methods. 30 women from authentic SLE by criteria ACR, in the age of 20-45 years,
M E Zapryagaeva, E S Mach, A A Baranov
doaj   +1 more source

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