Results 61 to 70 of about 2,929 (206)

Vonoprazan treatment improves gastrointestinal symptoms in patients with gastroesophageal reflux disease

Kaohsiung Journal of Medical Sciences, 2017
The effects of vonoprazan, a new potassium-competitive acid blocker, on gastroesophageal reflux disease (GERD) symptom are not fully elucidated. The aim of this study is to determine the effect of vonoprazan on GERD and associated gastrointestinal ...
Satoshi Shinozaki, Hiroyuki Osawa, Yoshikazu Hayashi, Hirotsugu Sakamoto, Yoshimasa Miura, Alan Kawarai Lefor, Hironori Yamamoto   +6 more
doaj   +1 more source

A Case of Gastric Atypical Lipomatous Tumor/Well‐Differentiated Liposarcoma With Endoscopic Morphological Changes

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Atypical lipomatous tumor/well‐differentiated liposarcoma is a locally aggressive mesenchymal neoplasm composed of adipocytes and stromal cells. Gastric cases are exceedingly rare, and their malignant potential remains unclear. We report a case of a woman in her 60s who was found to have multiple submucosal tumor‐like lesions of the stomach ...
Rika Omote, Shizuma Omote, Hiroshi Sonobe, Ryosuke Hamano, Tatsuya Toyokawa, Shinya Otsuka, Takehiro Tanaka, Hiroyuki Yanai, Masaru Inagaki, Hidetaka Yamamoto   +9 more
wiley   +1 more source

Comparison of vonoprazan and proton pump inhibitors for the treatment of gastric endoscopic submucosal dissection-induced ulcer: an updated systematic review and meta-analysis

BMC Gastroenterology
Background Both vonoprazan and proton pump inhibitors (PPIs) are currently used to treat artificial ulcers after gastric endoscopic submucosal dissection. However, evidence-based medicine proving the efficacy of vonoprazan is still lacking.
Lizhen Chen, Dalei Jiang, Doudou Hu, Xianghua Cui   +3 more
doaj   +1 more source

Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial

Gastroenterology Research and Practice, 2018
Background. Vonoprazan affords more clinical benefits than proton pump inhibitors (PPIs) during the healing of gastroduodenal ulcers. However, it remains controversial whether vonoprazan is more effective than PPIs when used to heal artificial ulcers ...
Yasuaki Ishii, Hiroaki Yamada, Takeshi Sato, Soichiro Sue, Hiroaki Kaneko, Kuniyasu Irie, Tomohiko Sasaki, Toshihide Tamura, Ryosuke Ikeda, Takehide Fukuchi, Ryosuke Kobayashi, Makomo Makazu, Chiko Sato, Kingo Hirasawa, Masaaki Kondo, Wataru Shibata, Shin Maeda   +16 more
doaj   +1 more source

Vonoprazan: a promising advancement in proton pump inhibitor therapy [PDF]

Vonoprazan, a potent potassium-competitive acid blocker (P-CAB), has emerged as a potential therapeutic option for acid-related disorders, particularly gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD).
Kaushal, Jyoti, Mittal, Niti, Vinayagam, Shanmugapriya   +2 more
core   +2 more sources

Influence of clarithromycin on the bactericidal effect of amoxicillin in patients infected with clarithromycin-resistant strains of H. pylori [PDF]

, 2020
Suzuki et al. reported that the VA-Dual therapy was better at eradicating the clarithromycin-resistant strains of H. pylori than the VAC-Triple therapy.
Furuta, Takahisa, Hamaya, Yasushi, Higuchi, Tomohiro, Iwaizumi, Moriya, Kagami, Takuma, Miyajima, Hiroaki, Osawa, Satoshi, Sugimoto, Ken, Suzuki, Takahiro, Tani, Shinya, Umemura, Kazuo, Yamade, Mihoko   +11 more
core   +1 more source

Visibility Evaluation of Fundic Gland Polyp Associated With Proton Pump Inhibitor in Texture and Color Enhancement Imaging

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives A ‘gray color sign’ (GCS) is a new endoscopic feature of fundic gland polyp associated with proton pump inhibitor (PPI‐FGP). Here, we compare the ability of texture and color enhancement imaging (TXI) to white light imaging (WLI) with regard to the detection of GCS. Methods In this prospective study, 19 consecutive patients with PPI‐
Ryota Uchida, Hiroya Ueyama, Tsutomu Takeda, Shunsuke Nakamura, Yasuko Uemura, Tomoyo Iwano, Momoko Yamamoto, Hisanori Utsunomiya, Daiki Abe, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Mariko Hojo, Shuko Nojiri, Takashi Yao, Akihito Nagahara   +17 more
wiley   +1 more source

Bioactive Compounds of the Ethanol Extract of Butterfly Pea Petals (Clitorea ternatea L.) on Gastric Proton Pump: In-Silico Analysis [PDF]

, 2023
Biodiversity of medicinal plants in Indonesia reflects the potential to be used to treat non-communicable diseases such as cancer. Gastritis is a kind of symptom felt in the stomach which may trigger severe abnormalities leading to a state of cancer ...
Kurniawati, Atik, Lestari, Sri Rahayu, Rohman, Fatchur   +2 more
core   +2 more sources

Proton Pump Inhibitor‐Induced Fundic Gland Polyps With Massive Bleeding Regressed on Alternative Histamine 2 Receptor Antagonist Therapy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract We report a case of massive bleeding from proton pump inhibitor (PPI)‐induced fundic gland polyps (FGPs) that regressed after switching to a histamine‐2 receptor antagonist (H2RA). A 46‐year‐old man with antiphospholipid syndrome had been receiving warfarin and lansoprazole for 4 years.
Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Yuto Matsuoka, Tomomi Hamaguchi, Aya Ikeda, Yoshihiro Goda, Soichiro Sue, Kuniyasu Irie, Shin Maeda   +9 more
wiley   +1 more source

Vonoprazan as an adjuvant to cisplatin: enhancing antitumor efficacy while mitigating nephrotoxicity and gastrointestinal adverse effects

Frontiers in Pharmacology
Background/ObjectiveCisplatin is a popular platinum-containing chemotherapeutic agent that has been used clinically since the 1970s to manage a wide range of hematologic and solid tumors. However, its therapeutic purpose is restricted by significant dose-
Faiz N. Alenezi, Marwa E. Abdelmageed, Marwa E. Abdelmageed, Manar A. Nader, Manar A. Nader, Marwa S. Zaghloul, Marwa S. Zaghloul   +6 more
doaj   +1 more source