Results 81 to 90 of about 2,929 (206)

Treatment response with potassium-competitive acid blockers based on clinical phenotypes of gastroesophageal reflux disease: A systematic literature review and meta-analysis [PDF]

BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) is typically managed based on the clinical phenotype. We evaluated the efficacy and safety of potassium-competitive acid blockers (PCABs) in patients with various clinical GERD phenotypes.
Gyawali, C Prakash, Jeong, Eui Sun, Jung, Hye-Kyung, Kim, Seong Eun, Lee, Hye Ah, Lim, Hyung Seok, Moon, Chang Mo, Seo, Seungyeon   +7 more
core   +2 more sources

Review Article: Classic Bismuth Quadruple Therapy for Helicobacter pylori Infection—Questions Focused on Clinical Practice

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 5, Page 616-636, March 2026.
BQT remains the most effective, safe, and practical regimen for H. pylori eradication, ensuring high cure rates across diverse resistance patterns and clinical settings. ABSTRACT Background Classic bismuth quadruple therapy (BQT)—the combination of a proton pump inhibitor, bismuth, tetracycline, and metronidazole—is a standard regimen for treating ...
Javier P. Gisbert, Pablo Parra, Olga P. Nyssen   +2 more
wiley   +1 more source

Susceptibility‐Guided Versus Empirical First‐Line Therapy of Helicobacter pylori Infection in Adults: A Systematic Review and Meta‐Analysis

Helicobacter, Volume 31, Issue 2, March/April 2026.
ABSTRACT Background Antimicrobial resistance undermines empirical first‐line regimens for Helicobacter pylori. We compared susceptibility‐guided therapy (SGT) versus empirical therapy in adults receiving first‐line treatment, focusing on intention‐to‐treat (ITT) eradication. Materials and Methods We searched MEDLINE (PubMed), Web of Science, and Scopus
Manuel Coelho Rocha, Tiago Gaspar, Carlos Bernardes, Pedro Pimentel Nunes   +3 more
wiley   +1 more source

Effects of Simvastatin on the Metabolism of Vonoprazan in Rats Both in vitro and in vivo

Drug Design, Development and Therapy, 2022
Yun Hong,1,* Da-Peng Dai,2,* Jian-Ping Cai,2 Shuang-Hu Wang,3 Yi-Ran Wang,1,4 Fang-Ling Zhao,2,4 Shan Zhou,2 Quan Zhou,3 Pei-Wu Geng,3 Yun-Fang Zhou,3 Xue Xu,1 Ji-Hua Shi,1 Qing-Feng Luo1 1Department of Gastroenterology, Beijing Hospital ...
Hong Y, Dai DP, Cai JP, Wang SH, Wang YR, Zhao FL, Zhou S, Zhou Q, Geng PW, Zhou YF, Xu X, Shi JH, Luo QF   +12 more
doaj  

Histamine2-Receptor Antagonists, Proton Pump Inhibitors, or Potassium-Competitive Acid Blockers Preventing Delayed Bleeding After Endoscopic Submucosal Dissection: A Meta-Analysis

Frontiers in Pharmacology, 2019
Background: Endoscopic submucosal dissection (ESD) was commonly used for en bloc resection in gastric cancer and adenoma with the risk of delayed bleeding after ESD.
Xin Jiang, Jiahao Li, Jiahao Li, Jingmei Xie, Zhuoru Liang, Ning Wan, Ning Wan, Jie Jiang, Jie Jiang, Tiantian Zhang, Tiantian Zhang, Tiantian Zhang, Yingyu Wu   +12 more
doaj   +1 more source

Efficacy of vonoprazan for the prevention of bleeding after gastric endoscopic submucosal dissection with continuous use of antiplatelet agents

Endoscopy International Open, 2020
Background Post-procedural bleeding, after gastric endoscopic submucosal dissection (ESD) for high risk thromboembolic cases that require continuous antiplatelet therapy, is challenging.
Shunsuke Yoshii, Takuya Yamada, Shinjiro Yamaguchi, Yoshito Hayashi, Masanori Nakahara, Narihiro Shibukawa, Masashi Yamamoto, Ryu Ishihara, Kazuo Kinoshita, Satoshi Egawa, Yoshiki Tsujii, Hideki Iijima, Tetsuo Takehara   +12 more
doaj   +1 more source

Second Asian Consensus Report on Functional Dyspepsia (2025): Updated Recommendations

Journal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 832-853, March 2026.
ABSTRACT Background Functional dyspepsia (FD) is a common gastrointestinal disorder that significantly impacts patients' quality of life. Over a decade ago, the Asian Neurogastroenterology and Motility Association (ANMA) and the Asian Pacific Association of Gastroenterology (APAGE) jointly developed the first Asian consensus report on FD.
Sanjiv Mahadeva, Kewin Tien Ho Siah, Uday C. Ghoshal, Hidekazu Suzuki, Yeong Yeh Lee, Kee Huat Chuah, Vincent Chung, Linda Zhong, Benjamin Wei‐Rong Tay, Ban Hong Ang, Ram Prasad Sinnanaidu, Tao Bai, Tadayuki Oshima, Tanisa Patcharatrakul, Sanjeev Sachdeva, Ping‐Huei Tseng, Jinsong Liu, Yinglian Xiao, Ratha‐Korn Vilaichone, Joon Seong Lee, Jung‐Hwan Oh, Ari Fahrial Syam, Ching Liang Lu, Tiing Leong Ang, In‐Kyung Sung, Xiao‐Hua Hou, Kentaro Sugano, Justin Wu, Hiroto Miwa   +28 more
wiley   +1 more source

Gatherings in Esophagology: Innovations and Future Directions in the Diagnosis and Management of Reflux Disease

Annals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
Bringing together experts in reflux diseases, including gastroenterologists, surgeons, endoscopists, laryngologists, pulmonologists, and research scientists, the inaugural Gatherings in Esophagology (GiE) was held May 30–31, 2025, in France as a new initiative of Organisation mondiale d'Etudes Spécialisées pour les maladies de l'Oesophage (OESO).
Jennifer Cable, Robert Giuli, Mark R. Fox, Rachel L. Rosen, Luis R. Valdovinos‐García, Stefano Siboni, John O. Clarke, Nikki Johnston, Tina L. Samuels, Carmelo Scarpignato, Ellen M. Stein, Ronnie Fass, José María Remes‐Troche, Abraham Khan, Afrin K. Rahman, Kristle Lynch, Daniela Jodorkovsky, Marcelo F. Vela, Alexandra Vandenberg, Braden Kuo, Pelin Ergun, Pichamol Jirapinyo, Emanuele Asti, Salvatore Tolone, Eric G. Sheu, Renato Salvador, Marco Sozzi, Inna A. Husain, Justin C. Wu, Anthony Hobson, Nirmal S. Sharma, Wai‐Kit Lo, Daniel R. Duncan, C. Prakash Gyawali, Walter W. Chan, Daniel Sifrim, Edoardo Savarino, Nicola de Bortoli, Benjamin D. Rogers   +38 more
wiley   +1 more source

Profound gastric mucosal changes and severe rebound acid hypersecretion after long‐term Vonoprazan use: A case report

DEN Open
Vonoprazan is a novel acid blocker with greater potency than proton pump inhibitors. A Japanese study reported no significant safety concerns over 5 years of Vonoprazan use; however, elevated serum gastrin and increased parietal cell and foveolar ...
Hiroko Suda, Sachi Eto, Koichi Sakurai
doaj   +1 more source

Simultaneous Estimation of Aspirin and Vonoprazan in Active Pharmaceutical Ingredient and pharmaceutical formulation by RP-HPLC [PDF]

A reliable, precise, and sensitive reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the simultaneous estimation of Aspirin and Vonoprazan in bulk drug and pharmaceutical formulations.
Madhvilatha, Jonnakuti, Mahajan, Niranjan Shishir, Nyola, Narendra Kumar   +2 more
core   +1 more source