Results 121 to 130 of about 47,572 (272)

Trichophyton indotineae: Epidemiology, antifungal resistance and antifungal stewardship strategies

Journal of the European Academy of Dermatology and Venereology, EarlyView.
There is a concerning trend of widespread and severe superficial fungal infections caused by a new pathogen—Trichophyton indotineae—resistant to standard antifungal therapies. T. indotineae is now spreading globally and evolving. There is increasing urgency for healthcare providers and policy makers to initiate surveillance systems and antifungal ...
Aditya K. Gupta, Susmita, Hien C. Nguyen, Amanda Liddy, Mesbah Talukder, Tong Wang, Lee Magal, Anuradha Chowdhary, Avner Shemer, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +11 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

The Changing Epidemiology of Breakthrough Invasive Fungal Disease in Allogeneic Hematopoietic Stem Cell Transplant Recipients in the Era of Modified‐Release Posaconazole Prophylaxis

Transplant Infectious Disease, EarlyView.
This single‐center retrospective cohort study on 300 allogeneic hematopoietic stem cell transplant recipients from January 2017 to May 2020, in which posaconazole modified release was the most common primary antifungal prophylaxis, demonstrated a breakthrough invasive fungal disease (bIFD) rate of 9%, with associated significant all‐cause mortality at ...
Shio Yen Tio, Chin Fen Neoh, David Ritchie, Lynette Chee, David C. M. Kong, Leon J. Worth, Michelle K. Yong, Monica A. Slavin   +7 more
wiley   +1 more source

Retrospective Assessment of Carbonic Anhydrase Inhibitors in Topical or Episcleral Implant Form for the Treatment of Equine Glaucoma

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To assess whether topical carbonic anhydrase inhibitors (CAIs) with or without episcleral brinzolamide implants control intraocular pressure (IOP) in horses with glaucoma. Animals Studied 12 client‐owned horses diagnosed with glaucoma.
Emily K. Tucker‐Retter, Maya Yamagata, Brian Gilger, Annie Oh   +3 more
wiley   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

A Rare Case of Blastomycosis in a Psoriasis Patient Treated With Ustekinumab (Stelara)

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Psoriasis is a chronic inflammatory skin condition mediated by T‐helper 1 (Th1) and T‐helper 17 (Th17) cytokines, including interleukin (IL)‐12, IL‐23, IL‐17, and tumor necrosis factor alpha (TNF‐α). Ustekinumab, a human monoclonal antibody against the p40 subunit of IL‐12/23, has revolutionized treatment of moderate to severe psoriasis but ...
Fatima Ghaffar, Ahmed Hassan, Masab Ali, Hafiz Noman Ijaz, Sajjad Jameel, Monika Kumari, Muhammad Husnain Ahmad   +6 more
wiley   +1 more source

Late‐Onset Invasive Aspergillosis With Pituitary Involvement and Dysfunction Following CD19 Chimeric Antigen Receptor T‐Cell Therapy

eJHaem, Volume 6, Issue 5, October 2025.
ABSTRACT Introduction Invasive fungal infection (IFI) after chimeric antigen receptor (CAR) T‐cell therapy is less common than bacterial and viral infections, but can be fatal once it develops. As most cases occur within 30 days after CAR T‐cell infusion, late‐onset IFI—particularly mould infection—appears to be under‐recognised.
Daisuke Ikeda, Tomohiro Nawada, Takumi Kondo, Takayuki Shinohara, Tomohiro Nagano, Saya Kubota, Ryuichiro Hiyama, Masaya Ueno, Hiroki Kobayashi, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Nobuharu Fujii, Masanori Makita, Yoshinobu Maeda   +16 more
wiley   +1 more source

Frequency and molecular epidemiology of Aspergillus isolated from patients with suspicion of respiratory fungal infection [PDF]

, 2019
Objective: The aim of this study was to determine the frequency of Aspergillus detected in respiratory samples from a cohort of patients with suspicion of fungal infection of the respiratory tract as well as to determine the susceptibility to azoles of ...
Oliveira, M., Sabino, R., Simões, H., Verissimo, C.   +3 more
core  

In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi [PDF]

, 1998
Elizabeth M. Johnson, Adrien Székely, David W. Warnock   +2 more
openalex   +1 more source

INTERNATIONAL MULTICENTER EXPERIENCE IN THE TREATMENT OF INVASIVE ASPERGILLOSIS IN IMMUNOCOMPROMISED CANCER PATIENTS

Mediterranean Journal of Hematology and Infectious Diseases, 2019
BACKGROUND: Invasive aspergillosis (IA) is a life-threatening infection in immunocompromised patients. In this study, we compared the efficacy of voriconazole containing regimen vs non-voriconazole containing regimen in patients with IA.
R. Hachem, Marjorie Batista, Souha S Kanj, Saaed El Zein, Sara Haddad, Ying Jiang, Nobuyoshi Mori, Rocha Vanderson, Anne-Marie Chaftari, Issam I Raad   +9 more
doaj   +1 more source