Results 101 to 110 of about 32,129 (220)
ABSTRACT Checkpoint inhibitor‐associated pneumonitis complicated by invasive pulmonary aspergillosis represents a diagnostic challenge in ICI‐treated patients, particularly those with COPD receiving corticosteroid therapy. Persistent or worsening respiratory abnormalities despite immunosuppressive treatment should prompt reassessment for superimposed ...
Chukwuka Elendu +3 more
wiley +1 more source
Voriconazole Induced Bradycardia
Voriconazole is a triazole antifungal drug that is used to treat invasive fungal infections, especially aspergillus. Here, we report two children who had severe bradycardia associated with voriconazole at a dose of 12 mg/kg per day.
Celkan, Tiraje +4 more
core +1 more source
Antifungal prophylaxis postheart transplant (HT) may include voriconazole or clotrimazole, which interact with tacrolimus. There is no guidance for tacrolimus adjustment when transitioning from voriconazole to clotrimazole; therefore, this study ...
Elizabeth Posney, PharmD +3 more
doaj +1 more source
Background: Antifungal prophylaxis (AFP) reduces the incidence of invasive fungal infections (IFIs) during induction therapy of acute myeloid leukemia (AML). Posaconazole is considered the standard of care.
Akash Shah +8 more
doaj +1 more source
ABSTRACT Catastrophic antiphospholipid syndrome (CAPS) is a fulminant and rare variant of antiphospholipid syndrome characterized by rapidly progressive multiorgan thrombosis and a high mortality rate. Its diagnosis is often challenging due to overlapping clinical features with sepsis, thromboembolic disorders, and systemic autoimmune diseases.
Nazmin Ahmed +4 more
wiley +1 more source
Failure of voriconazole to cure disseminated zygomycosis in an immunocompromised child [PDF]
Voriconazole is increasingly used as a first-line agent for empirical antifungal therapy of prolonged febrile neutropenia in paediatric cancer patients. We describe the case of a 9-year-old patient with stage IV Burkitt lymphoma, who developed pulmonary ...
Aebischer, C.C. +13 more
core +1 more source
IntroductionVoriconazole is widely used to prevent and treat invasive aspergillosis. However, its use is restricted by adverse effects, including acute liver injury (ALI).
Jing Ren +8 more
doaj +1 more source
Voriconazole metabolism is influenced by severe inflammation: a prospective study [PDF]
Item does not contain fulltextBACKGROUND: During an infection or inflammation, several drug-metabolizing enzymes in the liver are down-regulated, including cytochrome P450 iso-enzymes.
Touw, Daan J.; id_orcid +33 more
core +1 more source
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source

