Results 111 to 120 of about 32,129 (220)

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles

, 2015
Hyewon Chung,1,* Howard Lee,1,2,* HyeKyung Han,1 Hyungmi An,1 Kyoung Soo Lim,1,3 YongJin Lee,4 Joo-Youn Cho,1 Seo Hyun Yoon,1 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of ...
Jang IJ, Lim KS, Yoon SH, Cho JY, Yu KS, Han H, Lee H, An H, Lee YJ, Chung H   +9 more
core  

Posaconazole achieves prompt recovery of voriconazole-induced liver injury in a case of invasive aspergillosis

, 2018
Javier Martínez-Casanova,1 Nuria Carballo,1 Sonia Luque,1 Luisa Sorli,2 Santiago Grau1 1Pharmacy Department, Hospital del Mar, Barcelona, Spain; 2Infectious Diseases Department, Hospital del Mar, Barcelona, Spain Abstract: Azole antifungals have ...
Santiago Grau, Luque S, Carballo Martínez, Núria, Sorli Redó, M. Luisa, Luisa Sorli, Javier Martínez-Casanova, Grau S, Carballo N, Martínez-Casanova J, Sorli L, Luque Pardos, Sònia, Sonia Luque, Martínez-Casanova, Javier, Grau Cerrato, Santiago, Nuria Carballo   +14 more
core   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi, Masoud Kargar, Atefeh Kamali, Javad Yasbolaghi Sharahi   +3 more
wiley   +1 more source

Molecular Characterization and Antifungal Profiling of Nine Phenotypic Aspergillus nidulans Isolates: A Case Series From North India

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In a case series from a hospital in North India, A. nidulans strains isolated from patients with pulmonary aspergillosis were phenotypically identified and then underwent molecular characterization through sequencing of the amplified ITS1‐5.8S rDNA‐ITS2 region and antifungal susceptibility testing (AST) according to the CLSI M38A3 guidelines.
Aishwarya Nikhil, Atul Kumar Tiwari, Pearl Parashar, Mohit Bhatia, Ragini Tilak, Deepak Kumar, Sudhir Kumar Singh, Roger J. Narayan, Munesh K. Gupta   +8 more
wiley   +1 more source

Effects of voriconazole on Cryptococcus neoformans

, 2004
Voriconazole is a broad-spectrum triazole that offers extended activity against molds and yeasts that are not susceptible to earlier azole-type drugs. Recent studies indicate that melanization can severely reduce the susceptibility of certain antifungal ...
Casadevall A., Cleare W., Nosanchuk J.D., Van Duin D., Zaragoza O.   +4 more
core   +1 more source

An Evaluation of Foreign Clinical Data in the Approval Reviews of Antimicrobial Medicines in Japan: Considering Ethnic and Regional Differences in Data Extrapolations in Accordance With Regulatory Circumstances

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley   +1 more source

Diagnostic and Therapeutic Dilemmas in Recurrent Pulmonary Alveolar Proteinosis After Bilateral Lung Transplantation

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Pulmonary alveolar proteinosis (PAP) is an ultra‐rare lung disease that can recur even years after bilateral lung transplantation, as in this 73‐year‐old man whose diagnosis was delayed by PAS‐negative BAL and overlapping opportunistic infections (Nocardia, MAC, Aspergillus). Despite initially normal post‐transplant spirometry, he developed progressive
Omar Lopez, Deven Gupta, Shreya Podder, Ajay Wagh   +3 more
wiley   +1 more source

Tacrolimus Concentration/Dose Ratio in Hematopoietic Cell Transplantation Recipients: An Exploratory Study of Metabolizer Phenotyping and Clinical Outcomes

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Tacrolimus pharmacokinetics shows wide interindividual variability after allogeneic hematopoietic cell transplantation (HCT), potentially influencing both effectiveness and toxicity. The concentration‐to‐dose (C/D) ratio has been proposed as a simple surrogate marker of tacrolimus metabolism, enabling patient stratification into fast or slow ...
Luiz Carlos da Costa‐Junior, Rita de Cássia Barbosa da Silva Tavares, Marina Izu, Simone Cunha Maradei, Maria Claudia Rodrigues Moreira, Marta Colares Nogueira, Décio Lerner, Teresa de Souza Fernandez, Paulo Caleb Júnior Lima Santos   +8 more
wiley   +1 more source

Digital Surveillance After Allogeneic Hematopoietic Stem Cell Transplantation Guides Therapeutic Interventions to Reduce Non‐Relapse Mortality

European Journal of Haematology, Volume 116, Issue 6, Page 937-942, June 2026.
ABSTRACT Introduction Allogeneic hematopoietic stem cell transplantation (HSCT) offers curative potential for many hematological malignancies; however, outcomes may be adversely affected by infections and transplant‐associated complications, contributing to non‐relapse mortality (NRM).
Lara Bischof, Katharina Egger‐Heidrich, Martin Schneider, Gregor Friedrich, Anna Massow, Johanna Vogelsang, Franziska Schmidt, Matthias Hänel, Thomas Illmer, Lynn Leppla, Alexandra Teynor, Sabina de Geest, Gabriele Muelller, Klaus H. Metzeler, Martin Bornhäuser, Uwe Platzbecker, Jan Moritz Middeke, Vladan Vučinić   +17 more
wiley   +1 more source

Determination of voriconazole in human serum and plasma by micellar electrokinetic chromatography

, 2010
The micellar electrokinetic capillary chromatography (MEKC) separation and analysis of voriconazole and UK 115794 (internal standard) were examined and an assay for determination of voriconazole in human plasma and serum was developed.
Zimmerli, Stefan, Thormann, Wolfgang, Theurillat, Regula   +2 more
core   +1 more source