Results 71 to 80 of about 47,572 (272)
American Journal of Industrial Medicine, EarlyView.ABSTRACT Public health registries collect and maintain demographic and health data on a cohort of people with a common disease or exposure. While disease registries have proliferated in recent decades, registries comprising persons with potentially hazardous exposures—known commonly as exposure registries—are rare.
Sammy Almashat +3 more
wiley +1 more source
International Journal of Infectious Diseases, 2018 Objectives: The purpose of this study was to investigate the pharmacokinetic profile and safety of voriconazole treatment in patients with Child–Pugh class B and C cirrhosis. Methods: Liver cirrhosis patients who had received the recommended voriconazole
Taotao Wang +8 more
doaj +1 more source
Dental Research Journal, 2022 Background: Head-and-neck radiotherapy can change oral Candida species and cause candidiasis resistance to common antifungals by making the changes to the oral cavity environment. Voriconazole is a synthetic azole with extensive antifungal activity.
Zahra Golestannejad +8 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens +8 more
wiley +1 more source
Two cases of fungal keratitis caused by Metarhizium anisopliae [PDF]
, 2018 We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates
Burd, Eileen M +5 more
core +2 more sources
Voriconazole: a review of adjustment programs guided by therapeutic drug monitoring
Frontiers in PharmacologyObjectivesExploring adjustments to the voriconazole dosing program based on therapeutic drug monitoring results to implement individualized therapy.MethodsPubMed and Embase were systematically searched to obtain study about voriconazole dose adjustment ...
Li Jiang, Zhiqiang Lin
doaj +1 more source
Infection and Drug Resistance, 2022 Zhen Hu, Huaying Zhou Department of Infectious Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of ChinaCorrespondence: Huaying Zhou, Department of Infectious Diseases, The Second Xiangya ...
Hu Z, Zhou H
doaj
British Journal of Clinical Pharmacology, EarlyView.Due to extensive pathophysiological changes in critically ill patients, standard dosing of antibiotics may lead to inadequate drug exposure. This is concerning, as insufficient plasma drug concentrations may lead to treatment failure, whereas excessive drug exposure may increase the risk of toxic adverse events.
Sarah Dräger +12 more
wiley +1 more source
Influence of Inflammation on Voriconazole Metabolism [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT Voriconazole pharmacokinetics shows a large inter- and intrapatient variability. Inflammation is associated with changes in the expression of CYP isoenzymes. Here, we evaluated the influence of inflammation, marked by C-reactive protein (CRP) levels in blood, on the metabolism of voriconazole.
E. R. van den Heuvel +4 more
openaire +4 more sources
Chemistry &Biodiversity, EarlyView.ABSTRACT Plinia cauliflora (DC.) Kausel (jabuticaba) is traditionally used by Brazilian indigenous communities for therapeutic purposes, including the treatment of wounds and inflammation. This study investigated the phytochemical composition and biological activities of an ethanolic extract derived from P.
Priscila de Lima Paula +17 more
wiley +1 more source