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Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
Advanced Intelligent Discovery, EarlyView.This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Advanced Intelligent Discovery, EarlyView.Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
Overcoming the Nyquist Limit in Molecular Hyperspectral Imaging by Reinforcement Learning
Advanced Intelligent Discovery, EarlyView.Explorative spectral acquisition guide automatically selects informative spectral bands to optimize downstream tasks, outperforming full‐spectrum acquisition. The selected hyperspectral data are used for tasks such as unmixing and segmentation. BandOptiNet encodes selection states and outputs optimal bands to guide spectral acquisition. Recent advances
Xiaobin Tang +4 more
wiley +1 more source
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Caustics of the vortex beams generated by vortex lenses and vortex axicons
Journal of the Optical Society of America A, 2020In this work, the propagation of vortex beams is treated using a catastrophe theory approach. Analytic expressions are deduced to describe caustic surfaces produced by vortex lenses and vortex axicons. The obtained analytics allow us to explain the formation of the shadow region along the optical axis for vortex beams using ...
Sergey I. Kharitonov +3 more
openaire +2 more sources
Optics Letters, 2021
A class of wide-stationary optical sources with a specially designed degree of coherence profile is introduced for radiating spectral densities with a vortex whose core’s location and size can be controlled at a specified range. This is achieved by modeling of the source coherence state as a combination of a helicoidal separable phase and a Cartesian ...
Zhangrong Mei +3 more
openaire +2 more sources
A class of wide-stationary optical sources with a specially designed degree of coherence profile is introduced for radiating spectral densities with a vortex whose core’s location and size can be controlled at a specified range. This is achieved by modeling of the source coherence state as a combination of a helicoidal separable phase and a Cartesian ...
Zhangrong Mei +3 more
openaire +2 more sources
SPIE Proceedings, 2006
A novel method for tuning the orbital angular momentum (OAM) content of a vortex beam is presented. This approach makes use of the shaping of the odd and even components of the helical phase profile associated to the vortex. A relative azimuthal shift of the components results in the harmonic variation of the magnitude of the OAM density of the ...
C. López-Mariscal +1 more
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A novel method for tuning the orbital angular momentum (OAM) content of a vortex beam is presented. This approach makes use of the shaping of the odd and even components of the helical phase profile associated to the vortex. A relative azimuthal shift of the components results in the harmonic variation of the magnitude of the OAM density of the ...
C. López-Mariscal +1 more
openaire +1 more source
Journal of the Optical Society of America A, 2008
Hollow beam formation of radially and azimuthally polarized vortex beams, which has arbitrary topological charge, is analytically discussed under the strong focusing condition. The expressions for the electric fields of the focused vector-vortex beams are obtained based on a vector diffraction theory.
Shunichi, Sato, Yuichi, Kozawa
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Hollow beam formation of radially and azimuthally polarized vortex beams, which has arbitrary topological charge, is analytically discussed under the strong focusing condition. The expressions for the electric fields of the focused vector-vortex beams are obtained based on a vector diffraction theory.
Shunichi, Sato, Yuichi, Kozawa
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Engineering synthesized vortex beams
Proceedings of the 2022 Conference on Lasers and Electro-Optics Pacific Rim, 2022We propose an effective scheme to engineer the light tubes of vortex beams with predetermined geometries and controllable intensity profiles. This is beneficial to a broad range of applications such as particle trapping and micromachining.
Na Xiao +3 more
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Spatial intensity correlations of a vortex beam and a perfect optical vortex beam
Journal of the Optical Society of America A, 2019We present a model based on the Fresnel diffraction scheme for the spatial coherence function of random fields created by scattering optical vortex and perfect vortex beams. By using the spatial coherence function we showed analytically, numerically, and experimentally the dependence and independence of the speckle size of an optical vortex and perfect
Cristian Hernando, Acevedo +2 more
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Properties of circularly polarized vortex beams
Optics Letters, 2006The properties of circularly polarized vortex beams in cylindrical polarization bases are studied. A circularly polarized vortex beam is decomposed into radial and azimuthal polarization. With the proper combination of vortex charge and the handedness of the circular polarization, a focal field with an extremely strong longitudinal component as well as
Qiwen Zhan
exaly +3 more sources