Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes +6 more
wiley +1 more source
BackgroundBrain has been shown to undergo progressive atrophy in patients with Alzheimer’s disease (AD); however, more evidence is needed to elucidate how the brain structure changes during the progression to AD.
Xiaorui Cui +9 more
doaj +1 more source
Reciprocal anatomical relationship between primary sensory and prefrontal cortices in the human brain [PDF]
The human brain exhibits remarkable interindividual variability in cortical architecture. Despite extensive evidence for the behavioral consequences of such anatomical variability in individual cortical regions, it is unclear whether and how different ...
Kanai, Ryota +3 more
core +2 more sources
Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra +5 more
wiley +1 more source
Gait Adaptability Training Improves Gait in Spinocerebellar Ataxia Patients
Abstract Background Spinocerebellar ataxia (SCA) is a rare, genetic neurodegenerative movement disorder primarily affecting the cerebellum. So far, there is no available cure for SCA. However, evidence suggests that neurorehabilitation can alleviate symptoms.
Colette J.M. Reniers +5 more
wiley +1 more source
Use of the voxel-based morphometry method in the diagnosis of dementia of the Alzheimer type
In recent years, new data in neuroanatomy of patients with various neurodegenerative diseases, including Alzheimer’s disease, were obtained usingmagnetic resonance morphometry.
E. . Andreev +4 more
doaj
Significance of voxel-based morphometry in studying mild cognitive impairments
Cognitive impairments are an important medical and socialproblem associated with a high prevalence of this disease in thepopulation. 46% of patients develop dementia within 5 years afterthe diagnosis of mild cognitive impairments (MCIs ...
A. I. Damulina +2 more
doaj +1 more source
Early affective changes and increased connectivity in preclinical Alzheimer's disease. [PDF]
IntroductionAffective changes precede cognitive decline in mild Alzheimer's disease and may relate to increased connectivity in a "salience network" attuned to emotionally significant stimuli.
Bilgel, Murat +7 more
core +1 more source
Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing +22 more
wiley +1 more source
Terra incognita—cerebellar contributions to neuropsychiatric and cognitive dysfunction in behavioral variant frontotemporal dementia [PDF]
Although converging evidence has positioned the human cerebellum as an important relay for intact cognitive and neuropsychiatric processing, changes in this large structure remain mostly overlooked in behavioral variant frontotemporal dementia (bvFTD), a
Emma eDevenney +13 more
core +2 more sources

