Results 91 to 100 of about 67,095 (233)

Population pharmacokinetics of artemether–lumefantrine plus amodiaquine in patients with uncomplicated Plasmodium falciparum malaria

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 589-605, February 2026.
Aims Resistance to the artemisinins and the artemisinin‐based combination therapy (ACT) partner drugs has developed in Southeast Asia, and artemisinin resistance has also emerged in eastern Africa. Triple ACTs (triple artemisinin‐based combination therapies, TACT), consisting of two partner drugs with different mechanisms of action and similar ...
Junjie Ding, Richard M. Hoglund, Rob W. van der Pluijm, James J. Callery, Thomas J. Peto, Rupam Tripura, Sukanta Das, Nguyễn Hoàng Châu, Cholrawee Promnarate, Mavuto Mukaka, Lek Dysoley, Caterina Fanello, Marie A. Onyamboko, Anupkumar R. Anvikar, Mayfong Mayxay, Frank Smithuis, Lorenz von Seidlein, Mehul Dhorda, Chanaki Amaratunga, M. Abul Faiz, Ho Dang Trung Nghia, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Joel Tarning   +24 more
wiley   +1 more source

Construction and efficacy of recombinant Newcastle disease virus co-expressing VP2 and VP3 proteins of very virulent infectious bursal disease virus

Poultry Science
Infectious bursal disease (IBD), triggered by the infectious bursal disease virus (IBDV), poses a substantial risk to the poultry industry due to its immunosuppressive nature and the emergence of highly virulent strains.
Tongfei Liu, Lin Lin, Yun Pan, Xiaoling Lin, Ming Liang, Guanming Shao, Keyu Feng, Yaxin Liu, Xinheng Zhang, Qingmei Xie   +9 more
doaj   +1 more source

AAV Assembled Capsids Are Produced in Cells Blocked From Cell Cycle Progression

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 273-286, February 2026.
ABSTRACT Adeno‐associated virus (AAV) is a promising delivery system for gene therapy. However, current manufacturing of AAV suffers from very low yields compared to other biotherapeutics. The AAV dose per patient ranges between 1011and 1015 viral genomes (vg), requiring an average of 10 to 30 L production/dose.
Alaka Mullick, Audrey Morasse, Melanie Leclerc, Ziying Liu, Qing Yan Liu, Sonia Leclerc, Milica Momcilovic, Annie Viau, Amine A. Kamen   +8 more
wiley   +1 more source

Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]

, 2008
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric, Gutiérrez-Rivas, Monica, Pulido, Miguel R, Sobrino, Francisco, Sáiz, Margarita   +4 more
core   +3 more sources

A Plant-Produced Porcine Parvovirus 1-82 VP2 Subunit Vaccine Protects Pregnant Sows against Challenge with a Genetically Heterologous PPV1 Strain [PDF]

, 2022
Kyou-Nam Cho, In-Ohk Ouh, Youngmin Park, Minhee Park, Kyungmin Min, Hyangju Kang, Suyeong Yun, Jae‐Young Song, Bang‐Hun Hyun, Choi‐Kyu Park, Bo-Hwa Choi, Yoon-Hee Lee   +11 more
openalex   +1 more source

A bijection between unicellular and bicellular maps [PDF]

, 2013
In this paper we present a combinatorial proof of a relation between the generating functions of unicellular and bicellular maps. This relation is a consequence of the Schwinger-Dyson equation of matrix theory.
Han, Hillary S. W., Reidys, Christian M.
core  

Construction of Reverse Genetics System for Feline Calicivirus FCV‐BJ616 and Proteomic Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Chunmei Xu, Jingjie Zhao, Hao Liu, Haotian Gu, Xinming Tang, Lin Liang, Jiabo Ding, Shaohua Hou, Xiaomin Zhao, Ruiying Liang   +9 more
wiley   +1 more source

Production and purification of VP2 protein of porcine parvovirus expressed in an insect-baculovirus cell system

Virology Journal, 2010
The porcine parvovirus (PPV) VP2 protein was expressed in an insect-baculovirus cell system and was purified using Ni-NTA affinity column chromatography.
Cui Shangjin, Yao Guizhe, Zhou Hongchao
doaj   +1 more source

Efficacy and Safety of Hypofractionated Radiation Therapy Combined With Immunotherapy for Hepatocellular Carcinoma With Vp4 Portal Vein Tumor Thrombosis

Hepatology Research, Volume 56, Issue 2, Page 246-252, February 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) with Vp4 portal vein tumor thrombosis (PVTT) has an extremely poor prognosis, and evidence for effective systemic therapy is limited. Preclinical studies suggest that hypofractionated radiation therapy (HFRT) may enhance immune checkpoint inhibitor (ICI) efficacy through immunogenic cell death and ...
Masahiko Tameda, Hideaki Tanaka, Yutaka Toyomasu, Mizuki Kawachi, Hirono Owa, Mone Tsukimoto, Yasuyuki Tamai, Naoto Fujiwara, Ryuta Shigefuku, Suguru Ogura, Yoshihito Nomoto, Hayato Nakagawa   +11 more
wiley   +1 more source

Screening and Identification of a Chicken Dendritic Cell Binding Peptide by Using a Phage Display Library

Frontiers in Immunology, 2019
Dendritic cells (DCs), as antigen-presenting cells, can initiate adaptive immune responses efficiently. Although the DC-targeting strategy has attracted more attention, relevant studies on chicken are rare.
Sunting Ma, Sunting Ma, Sunting Ma, Xinyuan Qiao, Xinyuan Qiao, Yigang Xu, Yigang Xu, Li Wang, Han Zhou, Yanping Jiang, Wen Cui, Xuewei Huang, Xiaona Wang, Lijie Tang, Lijie Tang, Yijing Li, Yijing Li   +16 more
doaj   +1 more source