Results 91 to 100 of about 66,024 (210)

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, Volume 59, Issue 5, May 2026.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

Chaperonin TRiC/CCT subunit CCT7 is involved in the replication of canine parvovirus in F81 cells

Frontiers in Microbiology
Canine parvovirus (CPV) is one of the most common lethal viruses in canines. The virus disease is prevalent throughout the year, with high morbidity and mortality rate, causing serious harm to dogs and the dog industry.
Xia Su, Hongzhuan Zhou, Fuzhou Xu, Jin Zhang, Bing Xiao, Qi Qi, Lulu Lin, Bing Yang   +7 more
doaj   +1 more source

Profiling of Glycan Receptors for Minute Virus of Mice in Permissive Cell Lines Towards Understanding the Mechanism of Cell Recognition [PDF]

, 2013
The recognition of sialic acids by two strains of minute virus of mice (MVM), MVMp (prototype) and MVMi (immunosuppressive), is an essential requirement for successful infection.
Agbandje-McKenna, M, Chen, X, Cotmore, S, Cummings, RD, Dell, A, Halder, S, Haslam, SM, Heimburg-Molinaro, J, McKenna, R, North, SJ, Smith, DF, Tattersall, P, Trollope, AJ   +12 more
core   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

Advanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen, Yang Zhang, Zhe Li, Renjie Chai   +3 more
wiley   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

A bijection between unicellular and bicellular maps [PDF]

, 2013
In this paper we present a combinatorial proof of a relation between the generating functions of unicellular and bicellular maps. This relation is a consequence of the Schwinger-Dyson equation of matrix theory.
Han, Hillary S. W., Reidys, Christian M.
core  

A lecture on the Liouville vertex operators

, 2003
We reconsider the construction of exponential fields in the quantized Liouville theory. It is based on a free-field construction of a continuous family or chiral vertex operators.
Barnes E. W., Belavin A. A., Dorn H., Faddeev L. D., Faddeev L. D., Frenkel E., Gervais J.-L., J. TESCHNER, Ponsot B., Shintani T., Zamolodchikov A. B.   +10 more
core   +2 more sources

Coupling Matrix Representation of Nonreciprocal Filters Based on Time Modulated Resonators [PDF]

, 2019
This paper addresses the analysis and design of non-reciprocal filters based on time modulated resonators. We analytically show that time modulating a resonator leads to a set of harmonic resonators composed of the unmodulated lumped elements plus a ...
Alvarez-Melcon, A., Gomez-Diaz, J. S., Liu, X., Wu, X., Zang, J.   +4 more
core   +2 more sources

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1058-1068, April 2026.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi, Dean Hickman, Ulrika S. H. Simonsson   +6 more
wiley   +1 more source

Efficacy and Safety of Intensity‐Modulated Radiotherapy Combined With Regorafenib With or Without Immune Checkpoint Inhibitors as Second‐Line Treatment for Advanced Hepatocellular Carcinoma: A Real‐World Cohort Study From a Single Center

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Purpose This study aimed to assess the efficacy and safety of intensity‐modulated radiotherapy (IMRT) combined with regorafenib with or without immune checkpoint inhibitors (ICIs) as a second‐ or later‐line treatment for advanced hepatocellular carcinoma (HCC).
Lingxia Xin, Zhiyu Li, Yirui Zhai, Liming Wang, Feng Ye, Yongkun Sun, Wen Zhang, Tiago Biachi de Castria, Sanjaya K. Satapathy, Vishal G. Shelat, Shaffer R. S. Mok, Jennifer Wu, Shulian Wang, Yueping Liu, Yongwen Song, Yuan Tang, Hao Jing, Hui Fang, Shunan Qi, Ningning Lu, Ye‐Xiong Li, Xinyu Bi, Bo Chen   +22 more
wiley   +1 more source