Results 141 to 150 of about 1,145 (184)
Archives of Virology, 2008 Rabbit haemorrhagic disease (RHD) is a highly fatal disease caused by a virus of the family Caliciviridae. Whereas recombination is well documented in other members of this family, the extent of recombination has so far not been studied in RHDV. To reach a better evaluation of the possible role of recombination in the evolution of RHDV virulence, we ...
Joana Abrantes +2 more
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Plant Science, 2002 Abstract We have investigated the use of five different promoter-5′UTR leader combinations to develop a potato plant-based expression system for the production of VP60 protein from rabbit haemorrhagic disease virus (RHDV). The relative efficiency of CaMV 35S, modified CaMV 35S, sunflower polyubiquitin and patatin promoters, as well as the addition of
Sonia Castañón +6 more
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Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2020 Rabbit haemorrhagic disease virus (RHDV) and myxoma virus (MYXV), are two pathogens that have harmful effect on rabbit breeding and population decline of European rabbits in their native range, causing rabbit haemorrhagic disease (rabbit fever) and myxomatosis, respectively. The capsid protein VP60 of the RHDV represents the major antigenic protein. To
Yuan Wang, Qian Yu, Yi Li, Yanming Dong
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Antigenicity of VP60 structural proteinof rabbit haemorrhagic disease virus
Archives of Virology, 1997 Five overlapping segments of the VP60 capsid protein gene of rabbit haemorrhagic disease virus have been expressed in E. coli under the control of the T7 RNA polymerase. After purification, the antigenicity of these denatured protein segments has been studied by reactivity with sera from both naturally infected and vaccinated animals in Western blot ...
Elisenda Viaplana +2 more
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Production of high immunogenic VP60, a promising RHD-vaccine, in plants
Journal of Biotechnology, 2007 Heike Mikschofsky +5 more
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Expression of truncated CTB::VP60 in tobacco exhibited no immunogenicity in rabbits
Plant Science, 2011Despite several optimizations, the production of CTB::VP60 antigen fusion proteins in tobacco is still very low. This might be due to the size of the fusion partner VP60 (579 aa). Hence, two different N-terminal truncations of VP60 were fused to CTB, either with or without an ER retention signal.
Benjamin Lehmann +4 more
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VP60 The Importance Of Patient Organizations Involvement In Health Technology Assessment
International Journal of Technology Assessment in Health Care, 2017INTRODUCTION:In Europe, the work done by the European Commission and the European Network for Health Technology Assessment (EUnetHTA) has consolidated the role of Health Technology Assessment (HTA), and promises to better harmonize its impact across European Union (EU) countries.
Francesco De Lorenzo +3 more
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Expression behaviour of the fusion antigen CTB::VP60, a promising RHD-vaccine, in pea [PDF]
Journal für Verbraucherschutz und Lebensmittelsicherheit, 2007 The production of veterinary vaccines in transgenic plants appears to be an upcoming strategy. Since 15 years transgenic plants express a number of viral and bacterial antigens -amongst others VP60 (1, 2), the only structural capsid protein of the rabbit haemorrhagic disease virus (RHDV).
Heike Mikschofsky +4 more
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Egg yolk IgY against RHDV capsid protein VP60 promotes rabbit defense against RHDV infection
Veterinary Immunology and Immunopathology, 2013 VP60 capsid protein is the major structural and immunogenicity protein of RHDV (Rabbit hemorrhagic disease virus, RHDV), and has been implicated as a main protein antigen in RHDV diagnosis and vaccine design. In this report, egg yolk antibody (IgY) against N-terminal of VP60 was evaluated and developed as a new strategy for RHDV therapy.
Zai Xin Li +5 more
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Veterinary Microbiology, 2013
Rabbit hemorrhagic disease (RHD) is a contagious disease in adult rabbits, with high mortality, that occurs throughout the world. The VP60 protein has been implicated as main protein antigen in virus diagnosis and vaccine design. In this report, we describe the construction of a novel DNA vaccine (pcDNA-VP60) expressing the RHDV capsid protein (VP60 ...
Dongchun Guo +6 more
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Rabbit hemorrhagic disease (RHD) is a contagious disease in adult rabbits, with high mortality, that occurs throughout the world. The VP60 protein has been implicated as main protein antigen in virus diagnosis and vaccine design. In this report, we describe the construction of a novel DNA vaccine (pcDNA-VP60) expressing the RHDV capsid protein (VP60 ...
Dongchun Guo +6 more
openaire +3 more sources