Results 31 to 40 of about 1,145 (184)
Immunization with Potato Plants Expressing VP60 Protein Protects against Rabbit Hemorrhagic Disease Virus [PDF]
Journal of Virology, 1999 ABSTRACT The major structural protein VP60 of rabbit hemorrhagic disease virus (RHDV) has been produced in transgenic potato plants under the control of a cauliflower mosaic virus 35S promoter or a modified 35S promoter that included two copies of a strong transcriptional enhancer.
Sonia Castañón +7 more
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Expression of the Viral Antigen VP60 in Transgenic Potatoes and its Effect on the Nutritional Composition of Tubers [PDF]
Food and Nutrition Sciences, 2011 Recombinant plant-derived pharmaceuticals have been investigated for the last two decades and some products will soon be brought to market. Since veterinary pharmaceuticals seem to be the front-runners of plant-derived vaccines, we selected one model subunit vaccine, the structural capsid protein VP60 against rabbit haemorrhagic disease, and analyzed ...
Heike Mikschofsky +12 more
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Identification of Polish RHDVa subtype strains based on the analysis of a highly variable part of VP60 gene [PDF]
Polish Journal of Veterinary Sciences, 2012 In order to determine the genetic variability of Polish RHD virus strains and to confirm the presence of genetic variant (RHDVa) subtype the partial nucleotide sequences of capsid protein gene, including two highly variable regions C and E, were examined.
A. Fitzner +3 more
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Oral immunization of rabbits with VP60 particles confers protection against rabbit hemorrhagic disease [PDF]
Archives of Virology, 1996 Rabbit hemorrhagic disease virus (RHDV) causes more than 90% mortality in adult rabbits. In this study, the cDNA of the VP60 coding sequence of RHDV was cloned under the control of the polyhedrin and p10 promoters of baculovirus to be expressed in insect cells. The expression of RHDV VP60 under the control of the p10 promoter was 5-10 times higher than
Juan Plana-Durán +6 more
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Successful oral prime‐immunization with VP60 from rabbit haemorrhagic disease virus produced in transgenic plants using different fusion strategies [PDF]
Plant Biotechnology Journal, 2005 SummaryExpression levels of vaccine antigens in transgenic plants have important consequences in their use as edible vaccines. The major structural protein VP60 from the rabbit haemorrhagic disease virus (RHDV) has been produced in transgenic plants using different strategies to compare its accumulation in plant tissues.
Félix Gil-Dones +4 more
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Acta Biochimica Polonica, 2006 Rabbit hemorrhagic disease virus (RHDV) which causes a highly contagious disease of wild and domestic rabbits belongs to the family Caliciviridae. It is a small, positive single-stranded RNA virus with a genome of 7.5 kb and has a diameter of approximately 40 nm.
Beata Gromadzka +4 more
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Journal of General Virology, 2009 Rabbit hemorrhagic disease virus (RHDV) has two structural proteins: the major capsid protein VP60 and the minor capsid protein VP2. VP2 is speculated to play an important role in the virus life cycle. To investigate the effect of VP2 on VP60 expression, three types of experiment (baculovirus–insect cell system, mammalian–luciferase assay system and in
Liu Chen +8 more
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Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023 Rabbit hemorrhagic disease virus 2 (RHDV2 or Lagovirus europaeus GI.2) is spreading across North America. This has enabled submissions of lagomorphs for testing to veterinary diagnostic laboratories (VDLs). The liver is currently the gold‐standard sample type for testing by RT‐qPCR.
Javier Asin +7 more
wiley +1 more source
Вопросы вирусологии, 2023 Introduction. Rabbit hemorrhagic disease is an acute highly contagious infection associated with two genotypes of pathogenic Lagovirus. Antibodies to major capsid protein (Vp60) are protective.
Aleksey N. Mukhin +6 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 68, Issue 2, Page 509-518, March 2021., 2021 Abstract The Lagovirus genus comprises both pathogenic viruses as European brown hare syndrome virus (EBHSV‐ GII.1) and rabbit hemorrhagic disease viruses (RHDV‐GI.1 and RHDV2‐GI.2), that principally infect European brown hares (Lepus europeaus) and European rabbits (Oryctolagus cuniculus), respectively, causing severe necrotic hepatitis, spleen ...
Patrizia Cavadini +9 more
wiley +1 more source