Results 101 to 110 of about 3,084 (231)
Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]
, 2016 OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po +6 more
core +2 more sources
British Journal of Pharmacology, Volume 182, Issue 15, Page 3612-3627, August 2025.Abstract Background and Purpose Several G protein‐coupled receptors (GPCRs) are known to homodimerise. Dimeric GPCRs may have different properties from their monomers, but the molecular basis and functional significance of GPCR dimerisation remain largely unknown.
Satoshi Asano +6 more
wiley +1 more source
PACAP and its receptors in cranial arteries and mast cells
The Journal of Headache and Pain, 2018 Background In migraineurs pituitary adenylate cyclase activating peptide1–38 (PACAP1–38) is a potent migraine provoking substance and the accompanying long lasting flushing suggests degranulation of mast cells.
Inger Jansen-Olesen +1 more
doaj +1 more source
Journal of Cellular Physiology, Volume 240, Issue 7, July 2025.Caveolin1 interacts with PTH1R at membrane‐bound microdomains delaying receptor internalization, promoting cAMP signaling over calcium and ERK1/2 kinase pathways, and regulating bone formation and bone remodeling gene expression upon agonist stimulation in osteoblastic cells.
Sara Heredero‐Jiménez +7 more
wiley +1 more source
In Synch but Not in Step: Circadian Clock Circuits Regulating Plasticity in Daily Rhythms [PDF]
, 2016 The suprachiasmatic nucleus (SCN) is a network of neural oscillators that program daily rhythms in mammalian behavior and physiology. Over the last decade much has been learned about how SCN clock neurons coordinate together in time and space to form a ...
Evans, Jennifer A., Gorman, M. R.
core +2 more sources
The influence of epilepsy in synaptic plasticity in the hippocampus: neuroprotective role of VIP and its receptors [PDF]
, 2010 Tese de mestrado, Bioquímica, Universidade de Lisboa, Faculdade de Ciências, 2009O VIP (do Inglês ‘vasoactive intestinal peptide’) e um péptido neuromodulador que se encontra largamente distribuído no sistema nervoso central e periférico e tem um papel ...
Cruz, Armando Dulcídio da Silva
core
A receptor-based analysis of local ecosystems in the human brain. [PDF]
, 2017 BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core +1 more source
Rhinologic Conditions of Pregnancy: A Retrospective Cohort Study
OTO Open, Volume 9, Issue 2, April-June 2025.Abstract Objective To better understand the prevalence, risk factors, and management strategies of pregnancy‐related rhinologic conditions. Study Design Retrospective cohort study from January 2013 to January 2023. Setting Tertiary level Otolaryngology–Head and Neck Surgery clinic. Methods Pregnant patients with rhinologic concerns were included.
Yasmin Eltawil +2 more
wiley +1 more source
Journal of Neuroendocrinology, Volume 37, Issue 3, March 2025.The thera(g)nostic approach with somatostatin analog‐based agents extends beyond gastroenteropancreatic neuroendocrine tumors. Understanding tumor biological mechanisms is essential for optimizing treatment strategies. Abstract First isolated by Brazeau et al. in 1972, somatostatin (SST) is a neuropeptide known for regulating various signaling pathways
Giulia Santo +3 more
wiley +1 more source
International Journal of Genomics, Volume 2025, Issue 1, 2025.This study investigates the promoter region and regulatory elements of chicken insulin‐like growth factor (IGF) and vasoactive intestinal polypeptide (VIP) genes associated with reproductive traits. Several in silico tools, such as Neural Network Promoter Prediction (NNPP), Multiple Expectation maximizations for Motif Elicitation (MEME‐Suite), GC ...
Bosenu Abera +4 more
wiley +1 more source