Results 121 to 130 of about 3,084 (231)

Pharmacology of PACAP and VIP receptors in the spinal cord highlights the importance of the PAC1 receptor

British Journal of Pharmacology, Volume 181, Issue 15, Page 2655-2675, August 2024.
Background and Purpose The spinal cord is a key structure involved in the transmission and modulation of pain. Pituitary adenylate cyclase‐activating peptide (PACAP) and vasoactive intestinal peptide (VIP), are expressed in the spinal cord. These peptides activate G protein‐coupled receptors (PAC1, VPAC1 and VPAC2) that could provide targets for the ...
Zoe Tasma, Tayla A. Rees, Song Guo, Sheryl Tan, Simon J. O'Carroll, Richard L. M. Faull, Maurice A. Curtis, Sarah L. Christensen, Debbie L. Hay, Christopher S. Walker   +9 more
wiley   +1 more source

VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice. : VPAC2 Receptors Mediate VIP-Induced Neuroprotection

, 2005
Prepro-vasoactive intestinal peptide (VIP) mRNA codes for two neuropeptides: VIP and peptide histidine isoleucine (PHI). Two VIP receptors, shared with a similar affinity by pituitary adenylate cyclase-activating polypeptide (PACAP), have been cloned: VPAC(1) and VPAC(2). PHI binds to these receptors with a lower affinity.
Rangon, Claire-Marie, Goursaud, Stéphanie, Medja, Fadia, Lelièvre, Vincent, Mounien, Lourdes, Husson, Isabelle, Brabet, Philippe, Jégou, Sylvie, Janet, Thierry, Gressens, Pierre   +9 more
openaire   +1 more source

VPAC2 And/Or PAC1 Receptors Interact with NOS during Heat Stress in Humans

The FASEB Journal, 2010
VPAC2 and/or PAC1 receptors are implicated in cutaneous active vasodilation(AVD) during heat stress(HS). Nitric oxide(NO) from NOS also plays important roles in HS in humans. We hypothesized that NO and VPAC2/PAC1 interact in AVD during HS.
Joan L Zhao, Dean L Kellogg, Yubo Wu, John M Johnson   +3 more
openaire   +1 more source

Vasoactive intestinal polypeptide mediates circadian rhythms in Mammalian olfactory bulb and olfaction [PDF]

, 2014
Accumulating evidence suggests that the olfactory bulbs (OBs) function as an independent circadian system regulating daily rhythms in olfactory performance.
Granados-Fuentes, Daniel, Herzog, Erik D, Holy, Timothy E, Marpegan, Luciano, Miller, Jae-eun, Wang, Thomas   +5 more
core   +2 more sources

Role of PACAP and VIP Signalling in Regulation of Chondrogenesis and Osteogenesis [PDF]

, 2016
Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are multifunctional proteins that can regulate diverse physiological processes. These are also regarded as neurotrophic and anti-inflammatory substances in
A Akopian, A Hernanz, A Miyata, A Mobasheri, A Pan, A Sanchez, A Suzuki, A Szabo, AI Gogakos, B Botz, B Crombrugghe de, B Lv, B Sandor, B Winding, C Bataille, C Matta, CS Kovacs, CS Somogyi, D Li, D Reglodi, D Reglodi, D Reglodi, D Vaudry, E Banki, E Fabian, E Persson, EL Hohmann, G Chen, GN Onuoha, H Miraoui, H Ogawa, H Oka, H Okura, HH Strange-Vognsen, HJ Kwon, HJ Park, HW Ehlen, HW Lee, I Harfi, J Fodor, J Yang, JA Waschek, JH Jonason, JH Kim, JY Yan, K Csanaky, K Dohi, K Gelse, K Hayashi, K Schuhmann, K Tanaka, KA Pavelock, KB Paiva, L Pulsatelli, L Wang, L Zhao, M Barberi, M Carrion, M Hughes-Fulford, M Koppan, MB Goldring, MC Dvorakova, MD Payet, MJ Serrano, MM Heimesaat, MP Yavropoulou, N Ahmed, N Sangphech, N Sassi, N Shintani, P Gourlet, P Lundberg, P Niewiadomski, Q Lu, R Barrett-Jolley, R Brubel, R Yu, R Zakany, R Zakany, R Zakany, R Zhang, RL Pitts, RT Franceschi, S Giunta, S Hattori, S Onoue, S Piera-Velazquez, S Rahman, SJ Rozzi, T Juhasz, T Juhasz, T Juhasz, T Juhasz, T Juhasz, T Mustafa, TF Li, TW Moody, UH Lerner, V May, V Sethi, W Ma, Y Duan, Y Juarranz, Y Maeda, Y Rais, Y Zhang, YM Yoo, YT Konttinen   +107 more
core   +2 more sources

Neuroprotective Potential of Pituitary Adenylate Cyclase Activating Polypeptide in Retinal Degenerations of Metabolic Origin

Frontiers in Neuroscience, 2019
Pituitary adenylate cyclase-activating polypeptide (PACAP1-38) is a highly conserved member of the secretin/glucagon/VIP family. The repressive effect of PACAP1-38 on the apoptotic machinery has been an area of active research conferring a significant ...
Robert Gábriel, Robert Gábriel, Etelka Pöstyéni, Viktória Dénes   +3 more
doaj   +1 more source

Metabolic effects of secretin [PDF]

, 2013
postprin
Chow, BKC, Sekar, R
core   +1 more source

Transcriptional down-regulation of suppressor of cytokine signaling (SOCS)-3 in chronic obstructive pulmonary disease [PDF]

, 2013
Background: Tobacco is a leading environmental factor in the initiation of respiratory diseases and causes chronic obstructive pulmonary disease (COPD).
Dinh, Q. Thai, Fischer, Axel, Groneberg, Jan David Alexander, Peiser, Christian, Quarcoo, David, Scholz, Frank R., Springer, Jochen   +6 more
core   +1 more source

A novel selective VPAC2 agonist peptide-conjugated chitosan modified selenium nanoparticles with enhanced anti-type 2 diabetes synergy effects

International Journal of Nanomedicine, 2017
Shao-Jun Zhao,1,2,* De-Hua Wang,1,2 Yan-Wei Li,1,2 Lei Han,1,2 Xing Xiao,1,2 Min Ma,3,* David Chi-Cheong Wan,4 An Hong,1,2 Yi Ma1,2 1Institute of Biomedicine, Department of Cellular Biology, Jinan University, 2National Engineering Research Center of ...
Zhao SJ, Wang DH, Li YW, Han L, Xiao X, Ma M, Wan DC, Hong A, Ma Y   +8 more
doaj  

Expression and Distribution of Vasoactive Intestinal Polypeptide Receptor VPAC2 mRNA in Human Airways [PDF]

, 2001
David A. Groneberg, Petra Hartmann, Q. Thai Dinh, Axel W. Fischer   +3 more
openalex   +1 more source