Results 201 to 210 of about 3,084 (231)

Proline residue 280 in the second extracellular loop (EC2) of the VPAC2 receptor is essential for the receptor structure

Peptides, 2001
Inspection of the amino acid sequence of the human VPAC1 and the VPAC2 receptors after alignment of the conserved residues indicates that the second extracellular loop (EC2) is one amino acid shorter in the VPAC1 receptor due to the lack of a proline residue in position 294. We hypothesized that this could be of importance for receptor structure and/or
Vertongen, Pascale, Solano Haro, Rosa, Juarranz Moratilla, Maria Guillerma, Perret, Jason, Waelbroeck, Magali, Robberecht, Patrick   +5 more
openaire   +2 more sources

Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: Comparison with Asn216 in VPAC2 receptor

Cellular Signalling, 2006
After stimulation with agonist, G protein coupled receptors (GPCR) undergo conformational changes that allow activation of G proteins to transduce the signal, followed by phosphorylation by kinases and arrestin binding to promote receptor internalization.
Nachtergael, Ingrid, Gaspard, Nathalie, Langlet, Christelle, Robberecht, Patrick, Langer, Ingrid   +4 more
openaire   +2 more sources

IL‐4 regulates VIP receptor subtype 2 mRNA (VPAC2) expression in T cells in murine schistosomiasis

The FASEB Journal, 2000
In murine schistosomiasis, granuloma T cells express VPAC2 mRNA, whereas there is none in splenocytes. This suggests that T cell VPAC2 mRNA is inducible. To address this issue, spleno‐cytes from schistosome‐infected mice were incubated with anti‐CD3 to induce VPAC2 mRNA, which only appeared when cell cultures also contained anti‐IL‐
A, Metwali, A M, Blum, J, Li, D E, Elliott, J V, Weinstock   +4 more
openaire   +2 more sources

DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH VASOACTIVE INTESTINAL PEPTIDE RECEPTOR 2 (VPAC2)

2003
The invention provides a human VPAC2 which is associated with the disorders of the peripheral and central nervous system, cardio-vascular diseases, hematological diseases, genitourinary diseases, inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the peripheral and ...
BAYER AG, GOLZ STEFAN, BRUEGGEMEIER ULF, SUMMER HOLGER   +3 more
openaire   +1 more source

Circadian phenotype of double mutant PAC1/VPAC2 receptor knockout mice

Regulatory Peptides, 2012
J. Hannibal, J. Fahrenkrug
openaire   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly  

P616. The VPAC2 Receptor Mediates Fear Learning in Female, but Not Male Mice

Biological Psychiatry, 2022
Briana Chen, Abhishek Shah, Grace Shin, Holly Hunsberger, Christine Denny   +4 more
openaire   +1 more source

VPAC2 receptor, RO 251553, shows promise in asthma

Inpharma Weekly, 2003
openaire   +1 more source