Figure S1 from VPAC2 Receptor Signaling Promotes Growth and Immunosuppression in Pancreatic Cancer
<p>Supplementary Figure</p>
Tenzin Passang +10 more
+4 more sources
Vasoactive intestinal peptide excites GnRH neurons via KCa3.1, a potential player in the slow afterhyperpolarization current [PDF]
Frontiers in Cellular NeuroscienceVasoactive intestinal peptide (VIP) is an important component of the suprachiasmatic nucleus (SCN) which relays circadian information to neuronal populations, including GnRH neurons.
Stephanie Constantin +4 more
doaj +2 more sources
Pituitary adenylyl cyclase-activating polypeptide modulates the stress response: the involvement of different brain areas and microglia [PDF]
Frontiers in PsychiatryStress is necessary for survival. However, chronic unnecessary stress exposure leads to cardiovascular, gastrointestinal and neuropsychiatric disorders. Thus, understanding the mechanisms involved in the initiation and maintenance of the stress response ...
Anika Singh +4 more
doaj +2 more sources
Figure S5 from VPAC2 Receptor Signaling Promotes Growth and Immunosuppression in Pancreatic Cancer [PDF]
<p>Supplementary Figure</p>
Tenzin Passang +10 more
openalex +2 more sources
Probing the VIPR2 Microduplication Linkage to Schizophrenia in Animal and Cellular Models
Frontiers in Neuroscience, 2021 Pituitary adenylate cyclase-activating polypeptide (PACAP, gene name ADCYAP1) is a multifunctional neuropeptide involved in brain development and synaptic plasticity.
Yukio Ago +6 more
doaj +1 more source
A neuropeptide VIP induces cell migration by activating the PI3K pathway via VPAC2 receptors
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2022 Kairi Ozasa +7 more
openalex +3 more sources
The Circadian Clock Is Sustained in the Thyroid Gland of VIP Receptor 2 Deficient Mice
Frontiers in Endocrinology, 2021 VIP/VPAC2-receptor signaling is crucial for functioning of the circadian clock in the suprachiasmatic nucleus (SCN) since the lack results in disrupted synchrony between SCN cells and altered locomotor activity, body temperature, hormone secretion and ...
Birgitte Georg +5 more
doaj +1 more source
Molecular Basis of Class B GPCR Selectivity for the Neuropeptides PACAP and VIP
Frontiers in Molecular Biosciences, 2021 The related neuropeptides PACAP and VIP, and their shared PAC1, VPAC1 and VPAC2 receptors, regulate a large array of physiological activities in the central and peripheral nervous systems.
Chenyi Liao +4 more
doaj +1 more source
Role for VPAC2 Receptor-Mediated Signals in Pancreas Development [PDF]
Diabetes, 2003 Mature pancreatic cells develop from progenitors that proliferate and differentiate into endocrine and exocrine cells. This development is thought to be controlled by secreted soluble factors acting on their target cells after binding to membrane receptors. Here, we analyzed the impact on embryonic pancreatic development of ligands that bind to protein
Latif, Rachdi +2 more
openaire +2 more sources
European Journal of Histochemistry, 2022 Pituitary adenylate cyclase-activating polypeptide (PACAP) plays an important role in the steroidogenesis and spermatogenesis in the testis through its receptors PAC1, VPAC1, and VPAC2.
Zeqi Tang +7 more
doaj +1 more source