Results 61 to 70 of about 3,084 (231)
Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP1–23
Molecules, 2021 The search for efficacious treatment of neurodegenerative and progressive neuroinflammatory diseases continues, as current therapies are unable to halt or reverse disease progression.
Christopher R. Apostol +6 more
doaj +1 more source
PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. [PDF]
, 2018 The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large majority of migraine patients has resulted in considerable excitement in ...
Akerman, Simon +2 more
core +2 more sources
Nature Communications, 2020 Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al.
Andrew P. Patton +7 more
doaj +1 more source
Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]
, 2003 The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Alleaume, Céline +4 more
core +1 more source
HIV-1 integration is inhibited by stimulation of the VPAC2 neuroendocrine receptor
Virology, 2007 Successful HIV-1 infection requires a number of specific stages leading to integration of the provirus. We previously suggested that members of the VPAC neuroendocrine receptor family may play a role in HIV-1 infection. We now show that stimulation of the VPAC2 receptor with specific agonists provides strong resistance to HIV-1 infection.
Bokaei, Payman Baradar +3 more
openaire +2 more sources
Frontiers in Cellular Neuroscience, 2021 Pituitary adenylyl cyclase-activating polypeptide (PACAP) is a member of the vasoactive intestinal polypeptide (VIP)-the secretin-glucagon family of neuropeptides. They act through two classes of receptors: PACAP type 1 (PAC1) and type 2 (VPAC1 and VPAC2)
Jérôme Ruel +8 more
doaj +1 more source
The many faces of VIP in neuroimmunology: a cytokine rather a neuropeptide? [PDF]
, 2001 10 pages, 3 figures.-- PMID: 15333575 [PubMed].Neuroimmunomodulation has experienced an explosive growth not only in basic research, but expanding to the point that prospective clinical research could be now a reality.
Delgado, M., Pozo Pérez, David
core +1 more source
Frontiers in Neuroanatomy, 2020 Prolactin (PRL) is a versatile hormone and serves a broad variety of physiological functions besides lactation. The release of PRL from lactotrophs in the pituitary has in rodents been shown to be released with a circadian pattern depending on the ...
Ida Stangerup, Jens Hannibal
doaj +1 more source
Biology, 2022 Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate-Cyclase-Activating Peptide (PACAP) are anti-inflammatory neuropeptides that play important roles in human and rodent gut microbiota homeostasis and host immunity.
Emma Hawley +5 more
doaj +1 more source
VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus
Frontiers in Cellular Neuroscience, 2017 The enteric nervous system (ENS) situated within the gastrointestinal tract comprises an intricate network of neurons and glia which together regulate intestinal function. The exact neuro-glial circuitry and the signaling molecules involved are yet to be
Pieter Vanden Berghe +6 more
doaj +1 more source