Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. [PDF]
, 2019 Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Akiba, Yasutada +2 more
core
Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis
Journal of Neurochemistry, Volume 170, Issue 1, January 2026.Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal +3 more
wiley +1 more source
Scientific Reports, 2023 Macrophages are a major population of immune cells in solid cancers, especially colorectal cancers. Tumor-associated macrophages (TAMs) are commonly divided into M1-like (tumor suppression) and M2-like (tumor promotion) phenotypes.
Wararat Kittikulsuth +8 more
doaj +1 more source
Antibiotics, 2023 Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is a multifunctional neuropeptide that is widely distributed and conserved across species. We have previously shown that in teleost fish, PACAP not only possesses direct antimicrobial properties ...
Janet Velázquez +9 more
doaj +1 more source
Expression of VPAC1 in a murine model of allergic asthma [PDF]
, 2013 Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways.
Braun, Armin +4 more
core
Differential Regulatory Role of Pituitary Adenylate Cyclase–Activating Polypeptide in the Serum-Transfer Arthritis Model [PDF]
, 2015 OBJECTIVE: Pituitary adenylate cyclase-activating polypeptide (PACAP) expressed in capsaicin-sensitive sensory neurons and immune cells has divergent functions in inflammatory and pain processes.
Botz, Bálint +14 more
core +1 more source
Multifunctional Role of Pacap-Like Peptides in Molluscs [PDF]
, 2013 The purpose of this review is to highlight the role of pituitary adenylate cyclase-activating polypeptide (PACAP) in a range of physiological and behavioral processes of gastropod molluscs, Helix and Lymnaea.
Kiss, Tibor, Pirger, Zsolt
core +1 more source
Periosteum Organoid: Biomimetic Design Inspired From the Bone Healing Process
Exploration, Volume 5, Issue 6, December 2025.Periosteum is a key factor in bone regeneration and repair, and the development of periosteum organoids with the help of organoid technology can achieve accelerated bone regeneration. This review explores the structure and function of the periosteum, the design and application of periosteum organoids, and their potential integration with bone organoids,
Shuyue Hao +7 more
wiley +1 more source
Structural and functional divergence of growth hormone-releasing hormone receptors in early sarcopterygians: lungfish and Xenopus [PDF]
, 2013 The evolutionary trajectories of growth hormone-releasing hormone (GHRH) receptor remain enigmatic since the discovery of physiologically functional GHRH-GHRH receptor (GHRHR) in non-mammalian vertebrates in 2007.
Chow, BKC, Lee, TO, TAM, KV
core +1 more source
Visceral Adipose Tissue Inflammatory Factors (TNF-Alpha, SOCS3) in Gestational Diabetes (GDM): Epigenetics as a Clue in GDM Pathophysiology [PDF]
, 2020 Gestational diabetes (GDM) is among the most challenging diseases in westernized countries, affecting mother and child, immediately and in later life. Obesity is a major risk factor for GDM.
Henrich, Wolfgang +6 more
core +1 more source