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Interactions of Viral protein U (Vpu) with Cellular Factors

2009
Viral protein U (Vpu) is encoded by one of several accessory genes of HIV-1. Like the accessory gene products Vif and Vpr, Vpu targets host proteins such as CD4 for degradation via the recruitment of cellular multi-subunit ubiquitin ligases. Vpu also forms ion channels in cellular membranes. Through one or both of these attributes, Vpu antagonizes host
openaire   +2 more sources

Advanced VPU Features

2011
Torsten Kempf   +2 more
openaire   +1 more source

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

Cell Host and Microbe, 2009
Daniel Sauter   +2 more
exaly  

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