Results 11 to 20 of about 3,834 (193)

Antihemolytic and Thrombolytic Potential of Ocimum basilicum Seed Extract, Bioactive Compounds, and Docking With VanA Ligase in Vancomycin-Resistant Staphylococci [PDF]

Journal of Tropical Medicine
Ocimum basilicum is an important alternative source to explore diverse anti-infective compounds. In the present study, aqueous seed extract of O.
Khalaf F. Alsharif, Hazir Rahman
doaj   +3 more sources

Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability. [PDF]

PLoS Pathogens
Vancomycin has proven remarkably durable to resistance evolution by Staphylococcus aureus despite widespread treatment with vancomycin in the clinic. Only 16 cases of vancomycin-resistant S. aureus (VRSA) have been documented in the United States.
Samuel E Blechman, Erik S Wright
doaj   +3 more sources

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A [PDF]

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +3 more sources

MIC and MBC of Honey and Gold Nanoparticles against methicillin-resistant (MRSA) and vancomycin-resistant (VRSA) coagulase-positive S. aureus isolated from contagious bovine clinical mastitis

Journal of Genetic Engineering and Biotechnology, 2017
Staphylococcus aureus is one of the major causative agents of the bovine clinical mastitis. This study aimed to isolate and identify S. aureus from cases of bovine clinical mastitis followed by phenotypic detection of MRSA and VRSA.
Shimaa T. Omara
doaj   +2 more sources

Comparative Genomics of Vancomycin-Resistant Staphylococcus aureus Strains and Their Positions within the Clade Most Commonly Associated with Methicillin-Resistant S. aureus Hospital-Acquired Infection in the United States [PDF]

mBio, 2012
Methicillin-resistant Staphylococcus aureus (MRSA) strains are leading causes of hospital-acquired infections in the United States, and clonal cluster 5 (CC5) is the predominant lineage responsible for these infections.
Veronica N. Kos, Christopher A. Desjardins, Allison Griggs, Gustavo Cerqueira, Andries Van Tonder, Matthew T. G. Holden, Paul Godfrey, Kelli L. Palmer, Kip Bodi, Emmanuel F. Mongodin, Jennifer Wortman, Michael Feldgarden, Trevor Lawley, Steven R. Gill, Brian J. Haas, Bruce Birren, Michael S. Gilmore   +16 more
doaj   +2 more sources

Amelioratory Effect of Nanoconjugated Vancomycin on Spleen during VRSA-Induced Oxidative Stress [PDF]

Pathology Research International, 2011
Objective. The aim of the present study was to evaluate the possible antioxidant effects of nanoconjugated vancomycin against VRSA infection on select makers of oxidative damage and antioxidant status in spleen.Methods. A coagulase-positive VRSA strain was used for this study. VRSA infection was developed in Swiss mice by intraperitoneal injection of 5
Chakraborty, Subhankari Prasad, KarMahapatra, Santanu, Sahu, Sumanta Kumar, Pramanik, Panchanan, Roy, Somenath   +4 more
openaire   +3 more sources

Molecular Basis of Vancomycin Dependence in VanA-Type Staphylococcus aureus VRSA-9 [PDF]

Journal of Bacteriology, 2010
ABSTRACT The vancomycin-resistant Staphylococcus aureus VRSA-9 clinical isolate was partially dependent on glycopeptide for growth. The responsible vanA operon had the same organization as that of Tn 1546 and was located on a plasmid. The chromosomal
Meziane-Cherif, Djalal, Saul, Frederick, Moubareck, Carole, Weber, Patrick, Haouz, Ahmed, Courvalin, Patrice, Périchon, Bruno   +6 more
openaire   +3 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum [PDF]

Advanced Science, Volume 13, Issue 11, 23 February 2026.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +2 more sources

Nasal Colonizing Vancomycin‐Resistant and Intermediate Staphylococcus aureus Among Admitted Patients: A Hospital Based Cross‐Sectional Study [PDF]

Health Science Reports
Background and Aim Staphylococcus aureus colonizing the nasal cavity poses a potential risk for infections. Vancomycin is a primary treatment for invasive infections caused by penicillin and methicillin‐resistant S. aureus (MRSA).
Biniyam Kijineh Mengistu, Tsegaye Alemayehu, Techilo Habtemariam Mengesha, Musa Mohammed Ali   +3 more
doaj   +2 more sources

Methicillin- and Vancomycin-Resistant Staphylococcus aureus (MRSA and VRSA) in Raw and Cooked Buffalo Meat Products [PDF]

Foods
Buffalo meat is widely consumed in Egypt; however, it may pose serious food safety risks due to microbial contamination during handling, preparation, and processing. This study investigated the prevalence and characterization of multidrug-resistant (MDR)
Khalid Ibrahim Sallam, Mennat-Allah Ahmed Diaa, Kálmán Imre, Adriana Morar, Amira Ibrahim Zakaria, Hazem Ramadan   +5 more
core   +2 more sources