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The Oncolytic Virus VSV-GP Is Effective against Malignant Melanoma
Viruses, 2018 Previously, we described VSV-GP, a modified version of the vesicular stomatitis virus, as a non-neurotoxic oncolytic virus that is effective for the treatment of malignant glioblastoma and ovarian cancer. Here, we evaluate the therapeutic efficacy of VSV-
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Cell, 1983
Recently we described a saturable, high-affinity binding site for vesicular stomatitis virus (VSV) on the surface of Vero cells that appears to mediate viral infectivity. To isolate this binding site, we have extracted Vero cells with the detergent, octyl-beta-D-glucopyranoside.
R, Schlegel +3 more
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Recently we described a saturable, high-affinity binding site for vesicular stomatitis virus (VSV) on the surface of Vero cells that appears to mediate viral infectivity. To isolate this binding site, we have extracted Vero cells with the detergent, octyl-beta-D-glucopyranoside.
R, Schlegel +3 more
openaire +2 more sources
Limitation of VSV infection by the host's response to VSV-associated cellular antigens.
The Journal of Immunology, 1982Abstract It has been reported that during the maturation of enveloped viruses, host proteins such as H-2 antigens of the mouse associate with the budding viruses. This finding led us to investigate the possible biologic significance of this association.
T T, Hecht, W E, Paul
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Virology, 1982
Abstract Viral ribonucleoprotein (RNP) particles isolated from vesicular stomatitis virus (VSV)-infected cells synthesized genome-length, complementary viral RNA, in addition to viral messenger RNA, in the presence of uninfected HeLa S10 extracts. The newly synthesized viral RNA was assembled into an RNP-like structure.
V M, Hill, D F, Summers
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Abstract Viral ribonucleoprotein (RNP) particles isolated from vesicular stomatitis virus (VSV)-infected cells synthesized genome-length, complementary viral RNA, in addition to viral messenger RNA, in the presence of uninfected HeLa S10 extracts. The newly synthesized viral RNA was assembled into an RNP-like structure.
V M, Hill, D F, Summers
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Inducible Vesicular Stomatitis Virus (VSV) L Cell Line for Packaging of Recombinant VSV
Virus Genes, 2005Recently, recombinant vesicular stomatitis viruses (VSV) have been developed as high-level expression vectors which serve as effective vaccine vectors in animals. An ideal approach for VSV vector production would be the development of stable packaging cell lines that can produce vector particles without transfection step.
Seong-Karp, Hong +3 more
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Interaction of VSV leader RNA and nucleocapsid protein may control VSV genome replication
Cell, 1981The discovery of plus- and minus-strand leader RNAs (short RNAs that are the complement of the exact 3' ends of the viral minus-strand genome and plus-strand antigenome) in VSV-infected cells has led to a model of genome replication in which the viral nucleocapsid protein acts as a modulator of genome transcription and replication.
B M, Blumberg, M, Leppert, D, Kolakofsky
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Analysis of the RNA of defective VSV particles
Cell, 1974Abstract Viral mRNA isolated from infected cells and the virion RNA isolated from two classes of defective interfering particles have been analyzed by RNA-RNA duplex reactions. The results show that the RNA of both defective interfering particles is viral, not host in origin.
G, Stamminger, R A, Lazzarini
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Replicating-Competent VSV-Vectored Pseudotyped Viruses
2023Vesicular stomatitis virus (VSV) is prototype virus in the family of Rhabdoviridae. Reverse genetic platform has enabled the genetic manipulation of VSV as a powerful live viral vector. Replicating-competent VSV is constructed by replacing the original VSV glycoprotein gene with heterologous envelope genes. The resulting recombinant viruses are able to
Fei, Yuan, Aihua, Zheng
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THE PATHWAY OF VSV ENTRY INTO CELLS
2014Vesicular stomatitis virus (VSV) like other Rhabdoviruses use the endocytic pathway to gain entry into the cell. VSV is an enveloped virus with the spike glycoprotein (VSV G) which mediates receptor recognition at the cell surface and fusion with the endosomal membranes in a ph dependent manner.
Johnson Shem, Gruenberg Jean
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Science, 2010
![Figure][1] CREDIT: GE ET AL. Rhabdoviruses are a family of negative-stranded RNA viruses that includes rabies virus, which have a characteristic bullet shape. Though structures of individual rhabdovirus proteins have been reported, how these are organized into a bullet shape has ...
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![Figure][1] CREDIT: GE ET AL. Rhabdoviruses are a family of negative-stranded RNA viruses that includes rabies virus, which have a characteristic bullet shape. Though structures of individual rhabdovirus proteins have been reported, how these are organized into a bullet shape has ...
openaire +1 more source