Results 111 to 120 of about 76,465 (345)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Serum secreted phosphoprotein 1 level is associated with plaque vulnerability in patients with coronary artery disease

Frontiers in Immunology
BackgroundVulnerable plaque was associated with recurrent cardiovascular events. This study was designed to explore predictive biomarkers of vulnerable plaque in patients with coronary artery disease.MethodsTo reveal the phenotype-associated cell type in
Ke Huang, Ke Huang, Shuai Chen, Shuai Chen, Lin-Jun Yu, Lin-Jun Yu, Zhi-Ming Wu, Zhi-Ming Wu, Qiu-Jing Chen, Xiao-Qun Wang, Xiao-Qun Wang, Fei-Fei Li, Fei-Fei Li, Jing-Meng Liu, Jing-Meng Liu, Yi-Xuan Wang, Yi-Xuan Wang, Lin-Shuang Mao, Lin-Shuang Mao, Wei-Feng Shen, Wei-Feng Shen, Rui-Yan Zhang, Rui-Yan Zhang, Ying Shen, Lin Lu, Lin Lu, Yang Dai, Yang Dai, Feng-Hua Ding, Feng-Hua Ding   +29 more
doaj   +1 more source

Imaging Modalities to Identity Inflammation in an Atherosclerotic Plaque

Radiology Research and Practice, 2015
Atherosclerosis is a chronic, progressive, multifocal arterial wall disease caused by local and systemic inflammation responsible for major cardiovascular complications such as myocardial infarction and stroke.
Sunny Goel, Avraham Miller, Chirag Agarwal, Elina Zakin, Michael Acholonu, Umesh Gidwani, Abhishek Sharma, Guy Kulbak, Jacob Shani, On Chen   +9 more
doaj   +1 more source

Bayesian semiparametric inference for multivariate doubly-interval-censored data [PDF]

, 2010
Based on a data set obtained in a dental longitudinal study, conducted in Flanders (Belgium), the joint time to caries distribution of permanent first molars was modeled as a function of covariates.
De Iorio, Maria, Jara, Alejandro, Lesaffre, Emmanuel, Quintana, Fernando   +3 more
core   +3 more sources

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

Glia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz, Madison Doceti, JaQuinta Thomas, Abigayle Duffy, Morgan Coburn, Akhabue K. Okojie, Audrey Lee, Elizabeth Aidita Sou, Alban Gaultier, Ukpong B. Eyo   +9 more
wiley   +1 more source

Diagnostic potential of TSH to HDL cholesterol ratio in vulnerable carotid plaque identification

Frontiers in Cardiovascular Medicine
ObjectiveThis study aimed to investigate the predictive value of the thyroid-stimulating hormone to high-density lipoprotein cholesterol ratio (THR) in identifying specific vulnerable carotid artery plaques.MethodsIn this retrospective analysis, we ...
Meihua Lei, Shi-Ting Weng, Jun-Jun Wang, Song Qiao   +3 more
doaj   +1 more source

Simulation of deposit formation in particle laden flows [PDF]

, 2004
Fatty deposits formed on arterial walls lead to atherosclerosis but it is the interplay between these deposits and the vessel walls which govern the growth of plaque formation.
Buick, J.M., Collins, M.W., Cosgrove, J.A., Mulholland, A.J., Steves, B.A.   +4 more
core  

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS

Journal of Lipid Research, 2006
Vulnerable atherosclerotic plaques may be identified by their large lipid component, particularly liquid cholesteryl ester (CE), covered by a fibrous cap.
Frederick L. Ruberg, Jason Viereck, Alkystis Phinikaridou, Ye Qiao, Joseph Loscalzo, James A. Hamilton   +5 more
doaj   +1 more source

Adjunctive therapies to reduce thrombotic events in patients with a history of myocardial infarction : role of vorapaxar [PDF]

, 2015
© 2015 Farag et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) LicenseAcute myocardial infarction (AMI) is generally attributed to coronary atherothrombotic ...
Farag, Mohamed, Gorog, Diana A, Patel, Hiten   +2 more
core   +3 more sources