Results 111 to 120 of about 33,525 (258)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Effects of Lipid Lowering Therapies on Vulnerable Plaque Features: An Updated Narrative Review of the Literature. [PDF]

J Cardiovasc Dev Dis, 2023
Biccirè FG, Gatto L, La Porta Y, Pignatelli P, Prati F, Pastori D.   +5 more
europepmc   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Rapid Progression of a CT-Defined Vulnerable Coronary Plaque: A Multimodality Imaging Case Report

Case Reports in Cardiology
Rapid progression of vulnerable plaques due to intraplaque neovascularization and hemorrhage is deemed as an important process preceding plaque rupture leading to myocardial infarction.
B. S. H. Hagen, P. A. Diemen, M. J. Bom, S. P. Schumacher, A. C. van Rossum, A. Nap, M. P. Opolski, C. J. W. Verouden, I. Danad, P. Knaapen   +9 more
doaj   +1 more source

Ten‐Year Results of a Prospective Study on One‐Piece Zirconia Oral Implants for Single‐Tooth Reconstruction

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The intention of this 10‐year prospective cohort investigation was to clinically and radiographically investigate the outcomes of a one‐piece zirconia implant system for single‐tooth replacement. Materials and Methods A total of 65 patients received 66 single‐tooth implants restored with all‐ceramic crowns.
Ralf‐Joachim Kohal, Agneta Lith, Futoshi Komine, Junichi Honda, Benedikt C. Spies, Felix Burkhardt, Kirstin Vach   +6 more
wiley   +1 more source

Acute Coronary Syndrome with Non-Obstructive Plaque on Angiography and Features of Vulnerable Plaque on Intracoronary Optical Coherence Tomography. [PDF]

Diagnostics (Basel), 2023
Dall'Orto CC, Ferreira Lopes RP, Eurípedes LV, Pinto Filho GV, da Silva MR.   +4 more
europepmc   +1 more source

Histopathologic Validation of Grayscale Carotid Plaque Characteristics Related to Plaque Vulnerability

, 2016
Carol Mitchell, James H. Stein, Thomas D. Cook, Shahriar Salamat, Xiao Wang, Tomy Varghese, Daren C. Jackson, Carolina Sandoval-Garcia, Stephanie M. Wilbrand, Robert J. Dempsey   +9 more
openalex   +1 more source

Improving cardiovascular risk stratification through the derivation and validation of an elevated triglyceride‐glucose index

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background and Aims Triglyceride‐glucose (TyG) index, is an emerging prognostic biomarker in atherosclerotic cardiovascular disease (ASCVD). Validation of its clinical value and of clinically relevant prognostic cut‐off, remains an unmet need to integrate TyG into primary prevention protocols.
Georgios Mavraganis, Georgios Georgiopoulos, Stavros Athanasopoulos, Dimitrios Terentes‐Printzios, Georgios Zervas, Christina Konstantaki, Maria Eleni Koilakou, Sofia‐Panagiota Giannakopoulou, Maria‐Angeliki Dimopoulou, Christina Chrysochoou, Konstantinos Tsioufis, Christos Pitsavos, Evangelos Liberopoulos, Konstantinos Stellos, Charalambos Vlachopoulos, Demosthenes Panagiotakos, Kimon Stamatelopoulos   +16 more
wiley   +1 more source

Implications of inflammation and sex in lower extremity arterial disease

European Journal of Clinical Investigation, EarlyView.
The graphical abstract illustrates the role of inflammation and sex‐related differences in lower extremity artery disease (LEAD). Key inflammatory biomarkers associated with LEAD include C‐reactive protein (CRP), fibrinogen, interleukin‐6 (IL‐6), and D‐dimer, which contribute to vascular inflammation and atherosclerotic plaque formation in lower limb ...
Katja Schnidrig, Manovriti Thakur, Aleksandra Tuleja, Sarah Maike Bernhard, Heidi Noels, Drosos Kotelis, Marc Schindewolf, Yvonne Döring   +7 more
wiley   +1 more source

Significance of Intra-plaque Hemorrhage for the Development of High-Risk Vulnerable Plaque: Current Understanding from Basic to Clinical Points of View. [PDF]

Int J Mol Sci, 2023
Sakamoto A, Suwa K, Kawakami R, Finn AV, Maekawa Y, Virmani R, Finn AV.   +6 more
europepmc   +1 more source