Results 21 to 30 of about 46,146 (333)

Requiem for the ‘vulnerable plaque’ [PDF]

European Heart Journal, 2015
The concept of the so-called ‘vulnerable plaque’ has proved highly useful to guide research and thinking regarding the pathophysiology of the acute coronary syndromes (ACS). Yet, the time may have come to reconsider this construct, as knowledge has accumulated, the risk profile of the populace has shifted, and our current therapies have reshaped the ...
Libby, Peter, Pasterkamp, Gerard
openaire   +4 more sources

Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease

AGING MEDICINE, Volume 5, Issue 4, Page 272-280, December 2022., 2022
Amyloid plaques deposit on neurons in case of Alzheimer's Disease. Mitochondria play a vital role in pathogenesis of Alzheimer's Disease. Mitochondrial dysfunction can lead to formation of mPTP, alteration of complexes 1,3 and 4, deficits in bioenergetics with impaired mitochondrial biogenesis. Abstract It is widely recognized that Alzheimer's disease (
Faizan Ahmad, Punya Sachdeva
wiley   +1 more source

High systemic immune-inflammation index is associated with carotid plaque vulnerability: New findings based on carotid ultrasound imaging in patients with acute ischemic stroke

Frontiers in Neurology, 2022
Vulnerable carotid plaque is closely related to the occurrence of Ischemic stroke. Therefore, accurate and rapid identification of the nature of carotid plaques is essential. AS is a chronic immune inflammatory process. Systemic immune-inflammation index
Lianlian Zhang, Qi Lyu, Wenyan Zhou, Xia Li, Qinggan Ni, Shu Jiang, Guofu Shi   +6 more
doaj   +1 more source

Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]

Bull Math Biol 85, 37 (2023), 2022
Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv   +1 more source

Plaque regression and plaque stabilisation in cardiovascular diseases

Indian Journal of Endocrinology and Metabolism, 2013
Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke.
Tarun Dave, J Ezhilan, Hardik Vasnawala, Vinod Somani   +3 more
doaj   +1 more source

Imaging the Vulnerable Plaque

Journal of the American College of Cardiology, 2011
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Vancraeynest, D, Pasquet, A, Roelants, V, Gerber, Bernhard L, Vanoverschelde, Jean-Louis J   +4 more
openaire   +4 more sources

Predictors and morphological properties of culprit healed plaques in patients with angina pectoris

Clinical Cardiology, Volume 45, Issue 12, Page 1199-1210, December 2022., 2022
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao, Qianyun Guo, Yujing Cheng, Tianyu Zhu, Qian Ma, Yujie Zhou   +5 more
wiley   +1 more source

Pathology of the Vulnerable Plaque

Journal of the American College of Cardiology, 2006
The majority of patients with acute coronary syndromes (ACS) present with unstable angina, acute myocardial infarction, and sudden coronary death. The most common cause of coronary thrombosis is plaque rupture followed by plaque erosion, whereas calcified nodule is infrequent.
Frank D. Kolodgie, Allen P. Burke, Andrew Farb, Renu Virmani   +3 more
openaire   +3 more sources

Does high sugar intake really alter the oral microbiota?: A systematic review

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1376-1390, December 2022., 2022
Abstract Objectives Diet is one of the main factors influencing the diversity and interactions of the oral microbiota. The purpose of this study is to determine the impact of sugar intake on the microbial diversity and bacteria that predominate under these conditions.
María del Pilar Angarita‐Díaz, Cristian Fong, Claudia M. Bedoya‐Correa, Claudia L. Cabrera‐Arango   +3 more
wiley   +1 more source

Automated diagnosis of optical coherence tomography imaging on plaque vulnerability and its relation to clinical outcomes in coronary artery disease

Scientific Reports, 2022
This study sought to develop a deep learning-based diagnostic algorithm for plaque vulnerability by analyzing intravascular optical coherence tomography (OCT) images and to investigate the relation between AI-plaque vulnerability and clinical outcomes in
Hirohiko Niioka, Teruyoshi Kume, Takashi Kubo, Tsunenari Soeda, Makoto Watanabe, Ryotaro Yamada, Yasushi Sakata, Yoshihiro Miyamoto, Bowen Wang, Hajime Nagahara, Jun Miyake, Takashi Akasaka, Yoshihiko Saito, Shiro Uemura   +13 more
doaj   +1 more source