Results 31 to 40 of about 33,280 (247)

Single-cell atlas reveals different immune environments between stable and vulnerable atherosclerotic plaques

Frontiers in Immunology, 2023
IntroductionRegardless of the degree of stenosis, vulnerable plaque is an important cause of ischemic stroke and thrombotic complications. The changes of the immune microenvironment within plaques seem to be an important factor affecting the ...
Peicong Ge, Peicong Ge, Hao Li, Hao Li, Xiaolong Ya, Xiaolong Ya, Yiqiao Xu, Long Ma, Long Ma, Qiheng He, Qiheng He, Rong Wang, Rong Wang, Zechen Liu, Qian Zhang, Qian Zhang, Yan Zhang, Yan Zhang, Wenjing Wang, Dong Zhang, Dong Zhang, Dong Zhang, Jizong Zhao, Jizong Zhao   +23 more
doaj   +1 more source

Comparison of multilayer and single-layer coronary plaque models on stress/strain calculations based on optical coherence tomography images

Frontiers in Physiology, 2023
Mechanical stress and strain conditions are closely related to atherosclerotic plaque progression and rupture and have been under intensive investigations in recent years.
Mengde Huang, Akiko Maehara, Dalin Tang, Dalin Tang, Jian Zhu, Liang Wang, Rui Lv, Yanwen Zhu, Xiaoguo Zhang, Mitsuaki Matsumura, Lijuan Chen, Genshan Ma, Gary S. Mintz   +12 more
doaj   +1 more source

Finding the Vulnerable Plaque [PDF]

Clinical Cardiology, 2010
AbstractAt a recent Transcatheter Therapeutics meeting in San Francisco the PROSPECT Trial was presented by Dr. Greg Stone. Prospect stands for Providing Regional Observations to Study Predictors of Events in the Coronary Tree. This was a natural history study of atherosclerosis using multi‐modality intracoronary imaging to prospectively identify ...
openaire   +2 more sources

Geographical predisposition influences on the distribution and tissue characterisation of eccentric coronary plaques in non-branching coronary arteries: cross-sectional study of coronary plaques analysed by intravascular ultrasound

Cardiovascular Ultrasound, 2016
Background We investigated the influence of geographical predisposition on the spatial distribution and composition of coronary plaques. Methods Thirty coronary arteries were evaluated.
Hidenori Komiyama, Hitoshi Takano, Shunichi Nakamura, Masamichi Takano, Noritake Hata, Miyauchi Yasushi, Yoshihiko Seino, Kyoichi Mizuno, Wataru Shimizu   +8 more
doaj   +1 more source

Vulnerable Plaque:

Journal of Interventional Cardiology, 2003
In order to understand, treat, and prevent acute coronary syndromes we need to improve our ability to identify the rupture‐prone, vulnerable atherosclerotic coronary plaque. The diagnostic modalities that are currently available to clinical practice have not fulfilled this expectation, and newer diagnostic techniques based on the recently identified ...
Christodoulos, Stefanadis, Manolis, Vavuranakis, Pavlos, Toutouzas   +2 more
openaire   +2 more sources

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

Journal of Interdisciplinary Medicine, 2016
An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging
Nyulas Tiberiu, Chiţu Monica, Mester András, Jáni Laura, Condrea Sebastian, Opincariu Diana, Kovács István, Benedek Imre, Benedek Theodora   +8 more
doaj   +1 more source

The Use of Biomarkers for the Early Detection of Vulnerable Atherosclerotic Plaques and Vulnerable Patients. A Review

Journal of Cardiovascular Emergencies, 2016
Acute coronary syndromes represent the most severe consequences of atherosclerosis, most often triggered by the rupture of a coronary plaque, which, for various reasons, has become unstable.
Benedek Theodora, Maurovich-Horváth Pál, Ferdinandy Péter, Merkely Béla   +3 more
doaj   +1 more source

Vulnerable plaques and patients: state-of-the-art [PDF]

European Heart Journal, 2020
Abstract Despite advanced understanding of the biology of atherosclerosis, coronary heart disease remains the leading cause of death worldwide. Progress has been challenging as half of the individuals who suffer sudden cardiac death do not experience premonitory symptoms.
Mariusz Tomaniak, Yuki Katagiri, Rodrigo Modolo, Ranil de Silva, Ramzi Y Khamis, Christos V Bourantas, Ryo Torii, Jolanda J Wentzel, Frank J H Gijsen, Gijs van Soest, Peter H Stone, Nick E J West, Akiko Maehara, Amir Lerman, Antonius F W van der Steen, Thomas F Lüscher, Renu Virmani, Wolfgang Koenig, Gregg W Stone, James E Muller, William Wijns, Patrick W Serruys, Yoshinobu Onuma   +22 more
openaire   +5 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Sex-specific association between inflammation and endothelial function relevant gene and vulnerable carotid plaque

Frontiers in Physiology, 2022
Objectives: We aimed to explore sex-specific association between genes involved in inflammation and endothelial function and vulnerable carotid plaque, a subclinical precursor of ischemic stroke.Methods: Carotid plaque and plaque phenotype were assessed ...
Jie Li, Ping Zhang, Xingyang Yi, Hua Luo, Ming Yu, Hong Chen, Chun Wang   +6 more
doaj   +1 more source