Results 51 to 60 of about 1,471,775 (278)

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

Journal of Interdisciplinary Medicine, 2016
An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging
Nyulas Tiberiu, Chiţu Monica, Mester András, Jáni Laura, Condrea Sebastian, Opincariu Diana, Kovács István, Benedek Imre, Benedek Theodora   +8 more
doaj   +1 more source

Relationship of Neutrophil-to-Lymphocyte Ratio with Carotid Plaque Vulnerability and Occurrence of Vulnerable Carotid Plaque in Patients with Acute Ischemic Stroke

BioMed Research International, 2021
Background Carotid plaque is an undefined risk factor in ischemic stroke and is driven by inflammation. Mounting evidence suggests that neutrophil-to-lymphocyte ratio (NLR) is crucial not only for cerebrovascular events but also in atherosclerosis ...
Xin Li, Jing Li, Guo-De Wu
semanticscholar   +1 more source

The Use of Biomarkers for the Early Detection of Vulnerable Atherosclerotic Plaques and Vulnerable Patients. A Review

Journal of Cardiovascular Emergencies, 2016
Acute coronary syndromes represent the most severe consequences of atherosclerosis, most often triggered by the rupture of a coronary plaque, which, for various reasons, has become unstable.
Benedek Theodora, Maurovich-Horváth Pál, Ferdinandy Péter, Merkely Béla   +3 more
doaj   +1 more source

Predictors for Vulnerable Plaque in Functionally Significant Lesions.

JACC Cardiovascular Imaging
BACKGROUND Vulnerable plaque presents prognostic implications in addition to functional significance. OBJECTIVES The aim of this study was to identify relevant features of vulnerable plaque in functionally significant lesions.
Seokhun Yang, D. Hwang, K. Sakai, T. Mizukami, J. Leipsic, M. Belmonte, J. Sonck, B. Nørgaard, H. Otake, B. Ko, Michael Maeng, Jesper Møller Jensen, D. Buytaert, D. Munhoz, D. Andreini, H. Ohashi, T. Shinke, C. Taylor, Emanuele Barbato, B. de Bruyne, C. Collet, Bon-kwon Koo   +21 more
semanticscholar   +1 more source

From Detecting the Vulnerable Plaque to Managing the Vulnerable Patient: JACC State-of-the-Art Review.

Journal of the American College of Cardiology, 2019
The past decades have seen tremendous progress on elucidating mechanisms leading to acute coronary syndrome and sudden cardiac death. Pathology and imaging studies have identified features of coronary atherosclerosis that precede acute coronary events ...
A. Arbab-Zadeh, V. Fuster
semanticscholar   +1 more source

Vulnerable plaques and patients: state-of-the-art [PDF]

European Heart Journal, 2020
Abstract Despite advanced understanding of the biology of atherosclerosis, coronary heart disease remains the leading cause of death worldwide. Progress has been challenging as half of the individuals who suffer sudden cardiac death do not experience premonitory symptoms.
Mariusz Tomaniak, Yuki Katagiri, Rodrigo Modolo, Ranil de Silva, Ramzi Y Khamis, Christos V Bourantas, Ryo Torii, Jolanda J Wentzel, Frank J H Gijsen, Gijs van Soest, Peter H Stone, Nick E J West, Akiko Maehara, Amir Lerman, Antonius F W van der Steen, Thomas F Lüscher, Renu Virmani, Wolfgang Koenig, Gregg W Stone, James E Muller, William Wijns, Patrick W Serruys, Yoshinobu Onuma   +22 more
openaire   +5 more sources

Review of imaging biomarkers for the vulnerable carotid plaque

JVS: Vascular Science, 2021
Identification of carotid artery atherosclerosis is conventionally based on measurements of luminal stenosis. However, histopathologic studies demonstrate considerable differences between plaques with identical degrees of stenosis and indicate that ...
L. Saba, Nivedita Agarwal, R. Cau, C. Gerosa, R. Sanfilippo, M. Porcu, R. Montisci, G. Cerrone, Qi Yang, A. Balestrieri, P. Lucatelli, C. Politi, G. Faa, J. Suri   +13 more
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Imaging of the Vulnerable Carotid Plaque

Neurology, 2021
Panels A and B from Figure 1 are republished panels a and b from Figure 6 in the article “Imaging of the ulcerated carotid atherosclerotic plaque: a review of the literature” by V.

semanticscholar   +1 more source