Results 51 to 60 of about 78,688 (294)

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Sociodemographic determinants for oral health risk profiles [PDF]

open access: yes, 2010
The present study aimed to explore the association between caries risk profiles and different sociodemographic factors . The study sample (n = 104) was randomly selected within an urban population in Flanders, Belgium.
Vanobbergen, Jacques   +4 more
core   +2 more sources

Vulnerable Atherosclerotic Plaque [PDF]

open access: yesCirculation, 2003
The recent proliferation of invasive and noninvasive techniques to locate vulnerable atherosclerotic plaques raises important questions. Will such techniques add useful prognostic information? If so, will the information prevent myocardial infarction, stroke, or death in at least some patients at risk? Will it lead to new research advances?
Ward, Casscells   +2 more
openaire   +2 more sources

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

NOX2 inhibition stabilizes vulnerable plaques by enhancing macrophage efferocytosis via MertK/PI3K/AKT pathway

open access: yesRedox Biology, 2023
NADPH oxidases 2 (NOX2) is the main source of ROS in macrophages, which plays a critical role in the formation of atherosclerosis. However, effects of NOX2 inhibition on established vulnerable plaques and the potential role involved remain unclear.
Yue Wang   +7 more
doaj   +1 more source

A new approach for improving coronary plaque component analysis based on intravascular ultrasound images [PDF]

open access: yes, 2010
Virtual histology intravascular ultrasound (VH-IVUS) is a clinically available technique for atherosclerosis plaque characterization. It, however, suffers from a poor longitudinal resolution due to electrocardiogram (ECG)-gated acquisition.
Hetterich, Holger   +9 more
core   +3 more sources

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

The Impact of Coronary Artery Calcification on Long-Term Cardiovascular Outcomes

open access: yesJournal of Interdisciplinary Medicine, 2021
Decades of research and experimental studies have investigated various strategies to prevent acute coronary events. However, significantly efficient preventive methods have not been developed and still remains a challenge to determine if a coronary ...
Mitra Noémi   +5 more
doaj   +1 more source

Ultrasound lmaging-vulnerable plaque diagnostics: Automatic carotid plaque segmentation based on deep learning

open access: yesJournal of Radiation Research and Applied Sciences, 2023
Purpose: The purpose of this article is to develop a novel algorithm based on a kind of deep convolutional neural network for the automatic carotid plaque segmentation and stroke risk assessment from the carotid artery plaque using Doppler ultrasound ...
Xiao-xiao Chen   +6 more
doaj   +1 more source

Failed ISCHEMIA Trial or Failed Ischemia Testing? [PDF]

open access: yes, 2020
The results of the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approach) trial were presented at the American Heart Association Scientific Sessions in November, 2019 in Philadelphia, Pennsylvania, and ...
Budoff, Matthew J, Dahal, Suraj
core  

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