Results 61 to 70 of about 33,556 (247)

Classification of carotid atherosclerotic plaque components using T2 mapping technique from magnetic resonance imaging

Journal of Associated Medical Sciences, 2014
Introduction: Vulnerable plaque or soft plaque potentially increases risk of stroke. Accurate plaque characterization is a demand for treatments. To date, magnetic resonance imaging (MRI) using multiweighted images, T1 weighted (T1W), T2 weighted (T2E ...
Sranut Chunpenmongkol, Kittichai Wantanajittikul, Kittipan Rerkasem, Charin Ya-in, Suwit Saekho   +4 more
doaj  

Predictive Value of CCTA Plaque Characteristics for the Progression and Prognosis of Coronary Artery Stenosis

CT Lilun yu yingyong yanjiu
Objective: To investigate the value of qualitative and quantitative plaque characteristics on coronary computed tomography angiography (CCTA) in predicting coronary stenosis progression and prognosis.
Zhengteng LI, Min WANG, Dongmei PAN, Xiankai WANG   +3 more
doaj   +1 more source

Isolation, culturing and gene expression profiling of inner mass cells from stable and vulnerable carotid atherosclerotic plaques.

PLoS ONE, 2019
The connective tissue components that form the atherosclerotic plaque body are produced by the plaque inner mass cells (PIMC), located inside the plaque.
Olga A Novikova, Zhanna K Nazarkina, Anna V Cherepanova, Petr P Laktionov, Boris P Chelobanov, Ivan S Murashov, Roman V Deev, Evgeny A Pokushalov, Andrey A Karpenko, Pavel P Laktionov   +9 more
doaj   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Beyond the Lumen: Molecular Imaging to Unmask Vulnerable Coronary Plaques

Journal of Cardiovascular Development and Disease
Vulnerable coronary atherosclerotic plaque involves a dynamic pathophysiologic process within and surrounding an atheromatous plaque in coronary artery intima. The process drastically increases the risk of plaque rupture and is clinically responsible for
Geoffrey Currie, Hosen Kiat
doaj   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Vertebrobasilar artery geometry and quantitative high-resolution vessel wall MRI for stratifying vulnerable plaques in young and middle-aged adults with stroke risk factors

Frontiers in Medicine
ObjectiveTo investigate cross-sectional associations of vertebrobasilar arterial geometry and quantitative high-resolution vessel-wall imaging (HR-VWI) features with an HR-VWI-defined vulnerable plaque phenotype in individuals with stroke risk factors ...
Xin Liu, Bo Zheng, Lei Wang, Ye Zheng, Wenbin Luo, Gen Yan   +5 more
doaj   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

Advanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang, Nicolas Raison, Xuyang Zhang, Aijia Yang, Lukas Lindenroth, Shan Luo   +5 more
wiley   +1 more source