Results 71 to 80 of about 33,280 (247)

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Serum chemokines combined with multi-modal imaging to evaluate atherosclerotic plaque stability in patients undergoing carotid endarterectomy

Frontiers in Neurology
BackgroundAlthough imaging tools are crucial in identifying features of atherosclerotic plaque, there remains a lack of consensus on the use of serological markers for assessing high-risk plaques.MethodsPatients diagnosed with CAS who met the criteria ...
Xiaofan Yuan, Lei Guo, Hong Chen, Yang Gao, Fuqiang Guo, Jie Huang, Chuan Jiang, Zhenyu Wang   +7 more
doaj   +1 more source

Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS

Journal of Lipid Research, 2006
Vulnerable atherosclerotic plaques may be identified by their large lipid component, particularly liquid cholesteryl ester (CE), covered by a fibrous cap.
Frederick L. Ruberg, Jason Viereck, Alkystis Phinikaridou, Ye Qiao, Joseph Loscalzo, James A. Hamilton   +5 more
doaj   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source

Serum secreted phosphoprotein 1 level is associated with plaque vulnerability in patients with coronary artery disease

Frontiers in Immunology
BackgroundVulnerable plaque was associated with recurrent cardiovascular events. This study was designed to explore predictive biomarkers of vulnerable plaque in patients with coronary artery disease.MethodsTo reveal the phenotype-associated cell type in
Ke Huang, Ke Huang, Shuai Chen, Shuai Chen, Lin-Jun Yu, Lin-Jun Yu, Zhi-Ming Wu, Zhi-Ming Wu, Qiu-Jing Chen, Xiao-Qun Wang, Xiao-Qun Wang, Fei-Fei Li, Fei-Fei Li, Jing-Meng Liu, Jing-Meng Liu, Yi-Xuan Wang, Yi-Xuan Wang, Lin-Shuang Mao, Lin-Shuang Mao, Wei-Feng Shen, Wei-Feng Shen, Rui-Yan Zhang, Rui-Yan Zhang, Ying Shen, Lin Lu, Lin Lu, Yang Dai, Yang Dai, Feng-Hua Ding, Feng-Hua Ding   +29 more
doaj   +1 more source

Imaging Modalities to Identity Inflammation in an Atherosclerotic Plaque

Radiology Research and Practice, 2015
Atherosclerosis is a chronic, progressive, multifocal arterial wall disease caused by local and systemic inflammation responsible for major cardiovascular complications such as myocardial infarction and stroke.
Sunny Goel, Avraham Miller, Chirag Agarwal, Elina Zakin, Michael Acholonu, Umesh Gidwani, Abhishek Sharma, Guy Kulbak, Jacob Shani, On Chen   +9 more
doaj   +1 more source

Angioscopy Visualized a Residual Free‐Floating Thrombus in Mild Carotid Artery Stenosis Following Acute MCA Occlusion: A Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Carotid free‐floating thrombus (CFFT) is a rare yet severe cause of the ischemic stroke. Early identification and appropriate management are crucial to prevent recurrent embolic events. A 76‐year‐old man experienced sudden left‐sided hemiparesis and dysarthria.
Hirofumi Matsubara, Yusuke Egashira, Yukiko Enomoto, Tsuyoshi Izumo   +3 more
wiley   +1 more source

Influence of the Residual Gensini Score on Prognosis of Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The residual Gensini score (rGS) was developed to quantify the severity of coronary atheroma burden after coronary revascularisation. The predictive value of the rGS for clinical outcomes in patients with ST‐segment elevation myocardial infarction (STEMI) remains unexplored.
Batric Popovic, Nassima Djaballah, Mirela Tomic, Renaud Fay, Victorine Fraichot, Florian Eggenspieler, Pierre Adrien Metzdorf, Jeanne Varlot, Edoardo Camenzind   +8 more
wiley   +1 more source

Diagnostic potential of TSH to HDL cholesterol ratio in vulnerable carotid plaque identification

Frontiers in Cardiovascular Medicine
ObjectiveThis study aimed to investigate the predictive value of the thyroid-stimulating hormone to high-density lipoprotein cholesterol ratio (THR) in identifying specific vulnerable carotid artery plaques.MethodsIn this retrospective analysis, we ...
Meihua Lei, Shi-Ting Weng, Jun-Jun Wang, Song Qiao   +3 more
doaj   +1 more source

Correlation Between Calcification Characteristics of Carotid Atherosclerotic Plaque and Plaque Vulnerability

Therapeutics and Clinical Risk Management, 2021
Xiangli Xu,1 Yang Hua,2 Beibei Liu,2 Fubo Zhou,2 Lili Wang,2 Weihong Hou2 1Department of Ultrasound, the Second Hospital of Harbin, Harbin, People’s Republic of China; 2Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University ...
Xu X, Hua Y, Liu B, Zhou F, Wang L, Hou W   +5 more
doaj