Results 81 to 90 of about 1,471,775 (278)

Isolation, culturing and gene expression profiling of inner mass cells from stable and vulnerable carotid atherosclerotic plaques.

PLoS ONE, 2019
The connective tissue components that form the atherosclerotic plaque body are produced by the plaque inner mass cells (PIMC), located inside the plaque.
Olga A Novikova, Zhanna K Nazarkina, Anna V Cherepanova, Petr P Laktionov, Boris P Chelobanov, Ivan S Murashov, Roman V Deev, Evgeny A Pokushalov, Andrey A Karpenko, Pavel P Laktionov   +9 more
doaj   +1 more source

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

Advanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang, Nicolas Raison, Xuyang Zhang, Aijia Yang, Lukas Lindenroth, Shan Luo   +5 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Classification of carotid atherosclerotic plaque components using T2 mapping technique from magnetic resonance imaging

Journal of Associated Medical Sciences, 2014
Introduction: Vulnerable plaque or soft plaque potentially increases risk of stroke. Accurate plaque characterization is a demand for treatments. To date, magnetic resonance imaging (MRI) using multiweighted images, T1 weighted (T1W), T2 weighted (T2E ...
Sranut Chunpenmongkol, Kittichai Wantanajittikul, Kittipan Rerkasem, Charin Ya-in, Suwit Saekho   +4 more
doaj  

Predictive Value of CCTA Plaque Characteristics for the Progression and Prognosis of Coronary Artery Stenosis

CT Lilun yu yingyong yanjiu
Objective: To investigate the value of qualitative and quantitative plaque characteristics on coronary computed tomography angiography (CCTA) in predicting coronary stenosis progression and prognosis.
Zhengteng LI, Min WANG, Dongmei PAN, Xiankai WANG   +3 more
doaj   +1 more source

Multimodal photoacoustic imaging in analytic vulnerability of atherosclerosis

iRADIOLOGY, 2023
Atherosclerosis is a major cause of mortality and morbidity, and rupture can lead to myocardial infarction and stroke. The vulnerability assessment of atherosclerosis plaques is important for providing medical treatment.
Wangting Zhou, Duofang Chen, Kezhou Li, Zhen Yuan, Xueli Chen   +4 more
doaj   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Beyond the Lumen: Molecular Imaging to Unmask Vulnerable Coronary Plaques

Journal of Cardiovascular Development and Disease
Vulnerable coronary atherosclerotic plaque involves a dynamic pathophysiologic process within and surrounding an atheromatous plaque in coronary artery intima. The process drastically increases the risk of plaque rupture and is clinically responsible for
Geoffrey Currie, Hosen Kiat
doaj   +1 more source

Percutaneous Coronary Intervention for Vulnerable Coronary Atherosclerotic Plaque.

Journal of the American College of Cardiology, 2020
BACKGROUND Acute coronary syndromes most commonly arise from thrombosis of lipid-rich coronary atheromas that have large plaque burden despite angiographically appearing mild.
G. Stone, A. Maehara, Z. Ali, C. Held, M. Matsumura, L. Kjøller-Hansen, H. Bøtker, M. Maeng, T. Engstrøm, R. Wiseth, J. Persson, T. Trovik, Ulf J. Jensen, S. James, G. Mintz, O. Dressler, Aaron Crowley, O. Ben-Yehuda, D. Erlinge   +18 more
semanticscholar   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source