Results 41 to 50 of about 1,471,775 (278)

Coronary Computed Tomography Angiography Analysis of Calcium Content to Identify Non-culprit Vulnerable Plaques in Patients With Acute Coronary Syndrome

Frontiers in Cardiovascular Medicine, 2022
BackgroundAside from the culprit plaque, the presence of vulnerable plaques in patients with acute coronary syndrome (ACS) may be associated with future cardiac events.
Théo Pezel, Théo Pezel, Georgios Sideris, Jean-Guillaume Dillinger, Damien Logeart, Stéphane Manzo-Silberman, Alain Cohen-Solal, Florence Beauvais, Niveditha Devasenapathy, Jean-Pierre Laissy, Patrick Henry   +10 more
doaj   +1 more source

In Search of Vulnerable Plaque [PDF]

Circulation: Cardiovascular Imaging, 2012
Between 1970 and 2010, the number of cardiovascular deaths per 100 000 persons in the United States has fallen from ≈450 to ≈125, a reduction >70%.1 This marked decline in cardiovascular mortality represents one of the true success stories of modern medicine.
openaire   +2 more sources

CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques

Scientific Reports, 2020
Macrophages are a functionally heterogeneous group of immune cells abundant in atherosclerotic plaques. Macrophages expressing CD163 are associated with intraplaque hemorrhage and have previously been considered atheroprotective.
E. Bengtsson, K. Hultman, A. Edsfeldt, A. Persson, M. Nitulescu, J. Nilsson, I. Gonçalves, H. Björkbacka   +7 more
semanticscholar   +1 more source

Single-cell atlas reveals different immune environments between stable and vulnerable atherosclerotic plaques

Frontiers in Immunology, 2023
IntroductionRegardless of the degree of stenosis, vulnerable plaque is an important cause of ischemic stroke and thrombotic complications. The changes of the immune microenvironment within plaques seem to be an important factor affecting the ...
Peicong Ge, Peicong Ge, Hao Li, Hao Li, Xiaolong Ya, Xiaolong Ya, Yiqiao Xu, Long Ma, Long Ma, Qiheng He, Qiheng He, Rong Wang, Rong Wang, Zechen Liu, Qian Zhang, Qian Zhang, Yan Zhang, Yan Zhang, Wenjing Wang, Dong Zhang, Dong Zhang, Dong Zhang, Jizong Zhao, Jizong Zhao   +23 more
doaj   +1 more source

Reassessing the Mechanisms of Acute Coronary Syndromes: The “Vulnerable Plaque” and Superficial Erosion

Circulation Research, 2019
The mechanisms that underlie superficial erosion, a cause of coronary thrombosis distinct from plaque rupture, have garnered recent interest. In an era of improved control of traditional risk factors, such as LDL (low-density lipoprotein), plaque erosion
P. Libby, G. Pasterkamp, F. Crea, I. Jang   +3 more
semanticscholar   +1 more source

Early identification of carotid vulnerable plaque in asymptomatic patients

BMC Cardiovascular Disorders, 2020
Background This study was to explore the influencing factors of atherosclerotic plaque formation and stability in patients with asymptomatic carotid atherosclerotic plaques, so as to identify the vulnerable plaques at early stage, and then find high-risk
Yun-Gen Jiao, Yahong Qin, Zhen-Gang Zhang, Hao Zhang, Hai-Wei Liu, Chen Li   +5 more
semanticscholar   +1 more source

Geographical predisposition influences on the distribution and tissue characterisation of eccentric coronary plaques in non-branching coronary arteries: cross-sectional study of coronary plaques analysed by intravascular ultrasound

Cardiovascular Ultrasound, 2016
Background We investigated the influence of geographical predisposition on the spatial distribution and composition of coronary plaques. Methods Thirty coronary arteries were evaluated.
Hidenori Komiyama, Hitoshi Takano, Shunichi Nakamura, Masamichi Takano, Noritake Hata, Miyauchi Yasushi, Yoshihiko Seino, Kyoichi Mizuno, Wataru Shimizu   +8 more
doaj   +1 more source

Comparison of multilayer and single-layer coronary plaque models on stress/strain calculations based on optical coherence tomography images

Frontiers in Physiology, 2023
Mechanical stress and strain conditions are closely related to atherosclerotic plaque progression and rupture and have been under intensive investigations in recent years.
Mengde Huang, Akiko Maehara, Dalin Tang, Dalin Tang, Jian Zhu, Liang Wang, Rui Lv, Yanwen Zhu, Xiaoguo Zhang, Mitsuaki Matsumura, Lijuan Chen, Genshan Ma, Gary S. Mintz   +12 more
doaj   +1 more source

Vulnerable or High-Risk Plaque: A JACC: Cardiovascular Imaging Position Statement.

JACC Cardiovascular Imaging
The concept of high-risk plaque emerged from pathologic and epidemiologic studies 3 decades ago that demonstrated plaque rupture with thrombosis as the predominant mechanism of acute coronary syndrome and sudden cardiac death.
R. Vergallo, Seung-Jung Park, Gregg W. Stone, D. Erlinge, Italo Porto, R. Waksman, G. Mintz, F. D'Ascenzo, Sara Seitun, L. Saba, R. Vliegenthart, F. Alfonso, A. Arbab-Zadeh, Peter Libby, M. D. Di Carli, James E. Muller, Gerald Maurer, R. Gropler, Y. Chandrashekhar, E. Braunwald, Valentín Fuster, I. Jang   +21 more
semanticscholar   +1 more source

Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles

Theranostics, 2021
Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a target for identifying vulnerable plaques. However, challenges arise with the current in vivo imaging modalities for differentiating vulnerable atherosclerotic ...
Wei Tong, Hui Hui, Wen-Ting Shang, Ying-Qian Zhang, F. Tian, Qiang Ma, Xin Yang, Jie Tian, Yun-Dai Chen   +8 more
semanticscholar   +1 more source