Results 21 to 30 of about 78,688 (294)

Imaging the Vulnerable Plaque

Journal of the American College of Cardiology, 2011
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Vancraeynest, D, Pasquet, A, Roelants, V, Gerber, Bernhard L, Vanoverschelde, Jean-Louis J   +4 more
openaire   +3 more sources

High shear stress relates to intraplaque haemorrhage in asymptomatic carotid plaques [PDF]

, 2016
Background and aims Carotid artery plaques with vulnerable plaque components are related to a higher risk of cerebrovascular accidents. It is unknown which factors drive vulnerable plaque development.
Arias Lorza, A.M.A. (Andrés), Bruijne, M. (Marleen) de, Cibiş, M. (Merih), Franco, O.H. (Oscar), Lugt, A. (Aad) van der, Schuurbiers, J.C.H. (Johan), Selwaness, M. (Mariana), Speelman, L. (Lambert), Steen, A.F.W. (Ton) van der, Tuenter, A., Vernooij, M.W. (Meike), Wentzel, J.J. (Jolanda)   +11 more
core   +1 more source

Autoradiographical assessment of inflammation-targeting radioligands for atherosclerosis imaging: potential for plaque phenotype identification

EJNMMI Research, 2021
Purpose Many radioligands have been developed for the visualization of atherosclerosis by targeting inflammation. However, interpretation of in vivo signals is often limited to plaque identification. We evaluated binding of some promising radioligands in
Eric J. Meester, Erik de Blois, Boudewijn J. Krenning, Antonius F. W. van der Steen, Jeff P. Norenberg, Kim van Gaalen, Monique R. Bernsen, Marion de Jong, Kim van der Heiden   +8 more
doaj   +1 more source

b-Gamma-glutamyltransferase activity in human vulnerable carotid plaques. [PDF]

, 2014
Objective: The atherosclerotic plaque that is vulnerable to rupture and to superimposed thrombosis is mainly represented by a thin-cap fibroatheroma with or without ulceration/thrombosis and inflammatory infiltrates.
A. Paolicchi, A. Pucci, C. Passino, F. Basolo, M. Emdin, M. Ferrari, M. Franzini, M. Marconi, M. Matteucci, S. Ceragioli   +9 more
core   +1 more source

A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]

, 2014
For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
core   +3 more sources

Automated diagnosis of optical coherence tomography imaging on plaque vulnerability and its relation to clinical outcomes in coronary artery disease

Scientific Reports, 2022
This study sought to develop a deep learning-based diagnostic algorithm for plaque vulnerability by analyzing intravascular optical coherence tomography (OCT) images and to investigate the relation between AI-plaque vulnerability and clinical outcomes in
Hirohiko Niioka, Teruyoshi Kume, Takashi Kubo, Tsunenari Soeda, Makoto Watanabe, Ryotaro Yamada, Yasushi Sakata, Yoshihiro Miyamoto, Bowen Wang, Hajime Nagahara, Jun Miyake, Takashi Akasaka, Yoshihiko Saito, Shiro Uemura   +13 more
doaj   +1 more source

Non-invasive vulnerable plaque imaging: how do we know that treatment works? [PDF]

, 2014
Atherosclerosis is an inflammatory disorder that can evolve into an acute clinical event by plaque development, rupture, and thrombosis. Plaque vulnerability represents the susceptibility of a plaque to rupture and to result in an acute cardiovascular ...
Brevetti L, Cuocolo A, Esposito G, Giugliano G, Mainolfi C, Perrino C, Sannino A, Scudiero F, Stabile E, Toscano E, Trimarco B   +10 more
core   +1 more source

Coronary Computed Tomography Angiography Analysis of Calcium Content to Identify Non-culprit Vulnerable Plaques in Patients With Acute Coronary Syndrome

Frontiers in Cardiovascular Medicine, 2022
BackgroundAside from the culprit plaque, the presence of vulnerable plaques in patients with acute coronary syndrome (ACS) may be associated with future cardiac events.
Théo Pezel, Théo Pezel, Georgios Sideris, Jean-Guillaume Dillinger, Damien Logeart, Stéphane Manzo-Silberman, Alain Cohen-Solal, Florence Beauvais, Niveditha Devasenapathy, Jean-Pierre Laissy, Patrick Henry   +10 more
doaj   +1 more source

Human serum albumin nanoparticles loaded with phthalocyanine dyes for potential use in photodynamic therapy of atherosclerotic plaques [PDF]

, 2019
Diseases caused by obstruction or rupture of vulnerable plaques in the arterial walls such as cardiovascular infarction or stroke are the leading cause of death in the world.
Aljarilla, Ana, Banerjee, Shubhadeep, Escosura, Andres de la, Holappa, Lari, Krol, Silke, Martinelli, Chiara, Mäkinen, Petri I., Sengupta, Jayeeta, Setaro, Francesca, Szebeni, Janos, Torres, Tomas, Trohopoulos, Panagiotis N., Urbanics, Rudolf, Wu, LinPing, Ylä-Herttuala, Seppo   +14 more
core   +1 more source

Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?

Molecular Imaging, 2014
The need for noninvasive imaging to distinguish stable from vulnerable atherosclerotic plaques is evident. Activated macrophages play a role in atherosclerosis and express folate receptor folate receptor β (FR-β).
Leah C.J. Winkel, Harald C. Groen, Bibi S. van Thiel, Cristina Müller, Antonius F.W. van der Steen, Jolanda J. Wentzel, Marion de Jong, Kim Van der Heiden   +7 more
doaj   +1 more source