Results 11 to 20 of about 1,471,775 (278)

Targeted Therapy of Atherosclerosis Vulnerable Plaque by ROS-Scavenging Nanoparticles and MR/Fluorescence Dual-Modality Imaging Tracing [PDF]

Int J Nanomedicine, 2021
Purpose Early diagnosis and treatment of atherosclerosis (AS) vulnerable plaque has important clinical significance for the prognosis of patients. In this work, the integrated diagnosis and treatment nanoparticles based on Gd-doped Prussian blue (GPB ...
Yue Dai, X. Sha, Xiao-Xi Song, Xiuli Zhang, Mengyu Xing, Siwen Liu, Kai Xu, Jing-Jing Li   +7 more
semanticscholar   +2 more sources

Current Advances in the Diagnostic Imaging of Atherosclerosis: Insights into the Pathophysiology of Vulnerable Plaque

International Journal of Molecular Sciences, 2020
Atherosclerosis is a lipoprotein-driven inflammatory disorder leading to a plaque formation at specific sites of the arterial tree. After decades of slow progression, atherosclerotic plaque rupture and formation of thrombi are the major factors ...
Alexander Orekhov, Dongwei Zhang, Andrey Grechko   +2 more
exaly   +2 more sources

Vulnerable Atherosclerotic Plaque: Is There a Molecular Signature?

International Journal of Molecular Sciences, 2022
Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are the most common cause of death worldwide. The main pathophysiological mechanism for these complications is the rupture of vulnerable atherosclerotic plaques and ...
Mihaela Mocan, Roxana Mihaela Chiorescu
exaly   +2 more sources

Imaging the Vulnerable Plaque

Journal of the American College of Cardiology, 2011
Cardiovascular diseases are still the primary causes of mortality in the United States and in Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and precipitates an acute vascular event, which is responsible for the high mortality rate.
Jean-Louis Vanoverschelde, Bernhard L Gerber, Véronique Roelants   +2 more
exaly   +4 more sources

Vulnerable Plaque, Characteristics, Detection, and Potential Therapies

Journal of Cardiovascular Development and Disease, 2019
Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite current therapeutic developments, there is an unmet necessity in the prevention of atherosclerotic vascular disease. It remains a challenge to determine at an early
Anouar Hafiane
doaj   +2 more sources

Circulating protein biomarkers and their association with vulnerable plaque characteristics – a PROSPECT II substudy [PDF]

International Journal of Cardiology. Cardiovascular Risk and Prevention
Background: In the PROSPECT-II study, near infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) was used to characterize atherosclerotic plaques in the coronary arteries.
Tania Sharma, Akiko Maehara, Michael Maeng, Lars Kjøller-Hansen, Thomas Engstrøm, Ori Ben-Yehuda, Mitsuaki Matsumura, Ole Fröbert, Jonas Persson, Rune Wiseth, Alf Inge Larsen, Sasha Koul, Rebecca Rylance, Gary S. Mintz, Ziad A. Ali, Stefan K. James, Gregg W. Stone, David Erlinge   +17 more
doaj   +2 more sources

Inflammation mediates the relationship between cardiometabolic index and vulnerable plaque in patients with acute coronary syndrome [PDF]

Lipids in Health and Disease
Background As a novel indicator reflecting metabolic status and visceral adiposity distribution, the cardiometabolic index (CMI) has gained attention in cardiovascular risk stratification. This investigation employed optical coherence tomography (OCT) to
Haihao Yan, Sai Lv, Haiyao Pi, Haixu Yu, Weijun Yin, Yaran Wang, Yonghao Lan, Wei Liu   +7 more
doaj   +2 more sources

Significance of Intra-plaque Hemorrhage for the Development of High-Risk Vulnerable Plaque: Current Understanding from Basic to Clinical Points of View [PDF]

International Journal of Molecular Sciences, 2023
Atsushi Sakamoto, Rika Kawakami, Aloke Finn   +2 more
exaly   +2 more sources

A Plaque Instability Index Calculated by Histological Marker Analysis of the Endarterectomy Carotid Artery

Applied Sciences, 2022
(1) Background: Atherosclerosis is a pandemic condition that causes the development of ischemic syndromes including myocardial infarctions and many strokes, in addition to disabling peripheral artery disease.
Doina Butcovan, Veronica Mocanu, Mihai Enache, Beatrice Gabriela Ioan, Grigore Tinica   +4 more
doaj   +1 more source

Combining IVUS + OCT Data, Biomechanical Models and Machine Learning Method for Accurate Coronary Plaque Morphology Quantification and Cap Thickness and Stress/Strain Index Predictions

Journal of Functional Biomaterials, 2023
Assessment and prediction of vulnerable plaque progression and rupture risk are of utmost importance for diagnosis, management and treatment of cardiovascular diseases and possible prevention of acute cardiovascular events such as heart attack and stroke.
Rui Lv, Liang Wang, Akiko Maehara, Mitsuaki Matsumura, Xiaoya Guo, Habib Samady, Don P. Giddens, Jie Zheng, Gary S. Mintz, Dalin Tang   +9 more
doaj   +1 more source