The effect of serum MMP⁃9 and IL⁃6 on the vulnerability of carotid atherosclerotic plaque
Chinese Journal of Contemporary Neurology and Neurosurgery, 2012 Objective To explore the relationship of MMP⁃9 and IL⁃6 and the vulnerability of carotid atherosclerotic plaque. Methods According to the plaque vulnerability, 69 patients with acute cerebral infarction were divided into vulnerable plaque group (n = 35 ...
Wei WANG +5 more
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A new murine model of stress-induced complex atherosclerotic lesions
Disease Models & Mechanisms, 2013 SUMMARY The primary purpose of this investigation was to determine whether ApoE−/− mice, when subjected to chronic stress, exhibit lesions characteristic of human vulnerable plaque and, if so, to determine the time course of such changes.
Amir H. Najafi +14 more
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Protruding Aortic Plaque and Coronary Plaque Vulnerability
Journal of the American Heart AssociationBackground Protruding aortic plaque is known to be associated with an increased risk for future cardiac and cerebrovascular events. However, the relationship between protruding aortic plaque and coronary plaque characteristics has not been systematically investigated. Methods and Results
Haruhito Yuki +10 more
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The vulnerable atherosclerotic plaque: Understanding, identification and modification (American heart association monograph series) Edited by Valentin Fuster Coedited by J. F. Cornhill, R. E. Dinsmore, J. T. Fallon, W. Insull, P. Libby, S. Nissen, M. E. Rosenfeld, W. D. Wagner Futura Publishing Company, Inc., Armonk, N.Y. (1999) 418 pages, illustrated, $115.00 ISBN: 0‐87993‐406‐9 [PDF]
, 1999 Brian W. McCrindle
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A mathematical model for smooth muscle cell phenotype switching in atherosclerotic plaque [PDF]
arXivSmooth muscle cells (SMCs) play a fundamental role in the development of atherosclerotic plaques. SMCs may ingest lipids in a similar way to monocyte-derived macrophages (MDMs) in the plaque. This can stimulate SMCs to undergo a phenotypic switch towards a macrophage-like phenotype.
arxiv
Clinical Imaging of the High-Risk or Vulnerable Atherosclerotic Plaque [PDF]
, 2001 Zahi A. Fayad, Valentı́n Fuster
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Myeloperoxidase and Plaque Vulnerability [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Sudden cardiac death remains the leading cause of mortality in industrialized societies, outpacing all cancer related deaths combined. The majority of sudden cardiac deaths arise from acute myocardial infarction secondary to intracoronary artery thromboses. Remarkably, the culprit lesions involved are typically not flow-limiting stenoses,1,2 but rather
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Redox Biology, 2023 NADPH oxidases 2 (NOX2) is the main source of ROS in macrophages, which plays a critical role in the formation of atherosclerosis. However, effects of NOX2 inhibition on established vulnerable plaques and the potential role involved remain unclear.
Yue Wang +7 more
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Molecular Markers, Fibrous Cap Rupture, and the Vulnerable Plaque [PDF]
, 2001 Stephen M. Schwartz +2 more
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Are we ripe for preventive percutaneous coronary interventions?
REC: Interventional Cardiology (English Ed.)INTRODUCTION Preventive percutaneous coronary intervention (PCI) refers to the treatment of high-risk plaque before the occurrence of any adverse events.
Elvin Kedhi
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