Results 231 to 240 of about 1,043,722 (370)

Protecting vulnerable populations in extreme heat - a growing and pervasive health challenge. [PDF]

EBioMedicine
Schlader ZJ, Tourula E, Lignier MJ.
europepmc   +1 more source

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

Advanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen, Ying Li, Yan Yu, Mingze Cai, Hao Li, Minghe Huang, Guochao Yang, Jiageng Guo, Huailin Wang, Zhihong Song, Wei Shen, Huihui Jiang, Haitao Wu   +12 more
wiley   +1 more source

The emerging adulthood gap in diabetes prevention research

The Lancet Regional Health. Americas
Summary: Emerging adulthood, the period between ages 18 and 25, is distinct from older and younger populations in terms of both physiology and social circumstances.
Abigail Arons, Hilary K. Seligman
doaj  

Lifestyle Interventions in Cancer Survivors: Designing Programs That Meet the Needs of This Vulnerable and Growing Population

, 2007
Valeda B. Stull, Denise C. Snyder, Wendy Demark‐Wahnefried   +2 more
openalex   +1 more source

Public Health Consequences on Vulnerable Populations from Acute Chemical Releases [PDF]

, 2008
Perri Zeitz Ruckart, Maureen F. Orr
openalex   +1 more source

O‐GalNAc Glycosylation Activates MBL‐Mediated Complement and Coagulation Cascades to Drive Organotropic Metastasis

Advanced Science, EarlyView.
Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen, Wei Bao, Kaiyuan Liu, Na Jing, Genyu Du, Luyao Jiang, Qian You, Yingchao Zhang, Penghui Xu, Chaping Cheng, Nan Wang, Xialian Xi, Mingyue Wang, Yiyun Liu, Jinming Wang, Huifang Zhao, Shilei Zhang, Dinglan Wu, Chi‐Fai Ng, Jiahua Pan, Wei Xue, Wei‐Qiang Gao, Pengcheng Zhang, Kai Zhang, Helen He Zhu   +24 more
wiley   +1 more source

Vulnerability to eutrophication of a semi-annual life history: A lesson learnt from an extinct eelgrass (Zostera marina) population [PDF]

, 2009
Marieke M. van Katwijk, Arthur R. Bos, Peer A. F. Kennis, R. de Vries   +3 more
openalex   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

Unlocking Engagement: Enhancing Participation in Research With Vulnerable Populations. [PDF]

Int J Public Health
Rojas-Rozo L, Arsenault-Lapierre G, Dumaresq D, Trépanier T, Lea P, Myers Barnett K, O'Connor D, Fernandez Loughlin R, Miskucza K, Wighton MB, Godard-Sebillotte C, Gruneir A, Beuscart JB, Bronskill SE, Sourial N, Smith EE, Bethell J, Vedel I, COVID ROSA Research Team.   +18 more
europepmc   +1 more source

Climate Change and the Future Impacts of Storm-Surge Disasters in Developing Countries [PDF]

As the climate changes during the 21st century, larger cyclonic storm surges and growing populations may collide in disasters of unprecedented size. As conditions worsen, variations in coastal morphology will magnify the effects in some areas, while ...
Benoit Laplante, David Wheeler, Siobhan Murray, Susmita Dasgupta   +3 more
core   +1 more source