Results 231 to 240 of about 1,072,936 (352)

Ethically Governed AI for Educational Resilience: Leapfrogging Learning in Vulnerable Remote Populations

Sinclair, Delzetha Edith
openalex   +1 more source

Comment on Krüger, L. Decreasing Trends of Chinstrap Penguin Breeding Colonies in a Region of Major and Ongoing Rapid Environmental Changes Suggest Population Level Vulnerability. Diversity 2023, 15, 327 [PDF]

W. Chris Oosthuizen, Murray Christian, Mzabalazo Z. Ngwenya   +2 more
openalex   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Oral Health Status Among Children and Adolescents from Vulnerable Populations: A Cross-Sectional Study in Seville, Spain. [PDF]

Dent J (Basel)
Reyes-Lara RE, Curto A, Ribas-Perez D, Barbero-Navarro I, Rodriguez-Menacho D, Flores-Fraile J, Castaño-Séiquer A.   +6 more
europepmc   +1 more source

Global Hesitancy of COVID‐19 Vaccine Among Vulnerable Population From 2020 to 2023: A Systematic Review and Meta‐Analysis [PDF]

Qingsong Xu, Tianshuo Zhao, Xianming Cai, Mingting Wang, Le Ao, Tingting Wei, Yang Han, Sihui Zhang, Xiyu Zhang, Shifeng Jin, Xinyu Wang, Xin De Feng, Jiayi Zhao, Yifei Wu, Juan Yang, Fuqiang Cui   +15 more
openalex   +1 more source

Health of Vulnerable Populations

Academic Medicine, 2018
Valerie S, Palmer, Kathleen I, Birchfield, Peter S, Spencer   +2 more
openaire   +3 more sources

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

The Impact of a Digital Digestive Health Program and Telehealth Visits in Socially Vulnerable Populations: Cohort Evaluation. [PDF]

JMIR Form Res
Varma S, Black A, Commons E, Ho PC, Bravata DM, Liu H.   +5 more
europepmc   +1 more source

Vulnerable populations mentioned in peer-reviewed vs. grey literature by group based on Canadian-specific peer-reviewed sources (primary analysis).

Renée Schryer (22331732), Michala Norman (22331735), Manisha A. Kulkarni (8415366)   +2 more
openalex   +1 more source