Results 241 to 250 of about 1,072,936 (352)

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Social Determinants of Self-Reported Health in Vulnerable Populations During a Polycrisis in Lebanon.

JAMA Netw Open
Fayyad R, Ragi ME, Ghattas H, McCall SJ, Community Action for Equity in Pandemic Preparedness and Control (CAEP) Study Group.   +4 more
europepmc   +1 more source

Reducing patient waiting times in humanitarian settings: a data-driven approach to improving healthcare access for vulnerable populations. [PDF]

Arch Public Health
Alhawa EA, Presser E, Zahwe A, Faraj S, Al-Hajj S, Fares M, AlHalbi MF.   +6 more
europepmc   +1 more source

Establishing and Operating Welfare Shelters in the Aftermath of the 2024 Noto Peninsula Earthquake: A Case Study of Adaptive Management for Vulnerable Populations

Makoto Kosaka, Chika Yamamoto, Kazuko Ishikawa, Etsuko Nakamura, Momoka Yamamura, Ryo Ikeguchi, Yoshitaka Nishikawa, Toshiki Abe, Tianchen Zhao, Michioki Endo, Toyoaki Sawano, Nobuaki Moriyama, Akihiko Ozaki, Masaharu Tsubokura, Hiroyuki Beniya   +14 more
openalex   +1 more source

Privacy Challenges for Adolescents as a Vulnerable Population

, 2020
Afsaneh Razi, Zainab Agha, Neeraj Chatlani, Pamela Wiśniewski   +3 more
openalex   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

Advanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang, Zhishen Cai, Xingfeng Mao, Yixuan Zhang, Yunlong Pan, Jiawen Cheng, Xuechun Wang, Hengyi Song, Sasaki Takuya, Ming Lu, Gang Hu, Xiuxiu Liu, Yingmei Lu, Feng Han   +13 more
wiley   +1 more source

Inclusion of Women, Children, the Elderly, and Individuals With Underlying Medical Conditions: Prioritizing Vulnerable Populations in Clinical Research. [PDF]

Clin Infect Dis
Bruxvoort KJ, Bahakel H, Martin JM, Nayak JL, Rolsma SL, Healy CM, Creech CB.   +6 more
europepmc   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Profiling abuse and neglect of women with disabilities: a step towards prevention of mistreatment of vulnerable populations. [PDF]

Front Glob Womens Health
Savard J, Gavriilidis G, Lindblad A, Huang J, Zeitelhofer Adzemovic M.   +4 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source