Results 241 to 250 of about 1,043,722 (370)

PRMT3‐Mediated H4R3me2a Promotes Primary Age‐Related Tauopathy by Driving Tau Hyperphosphorylation in Neuron

open access: yesAdvanced Science, EarlyView.
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu   +9 more
wiley   +1 more source

Sentinel Surveillance of Sexually Transmitted Infections/HIV and Risk Behaviors in Vulnerable Populations in 5 Central American Countries

open access: bronze, 2007
R Soto   +9 more
openalex   +1 more source

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

open access: yesAdvanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz   +24 more
wiley   +1 more source

Community-based mortality surveillance among internally displaced vulnerable populations in Banadir region, Somalia, 2022-2023. [PDF]

open access: yesFront Public Health
Adam MH   +10 more
europepmc   +1 more source

Electronic Nanomaterials for Plants: A Review on Current Advances and Future Prospects

open access: yesAdvanced Electronic Materials, EarlyView.
Global food security faces mounting challenges from climate change and rapid population growth. This review highlights the pivotal role of electronic nanomaterials–including metals, metal oxides, and carbon‐based structures–in enhancing plant photosynthesis, nutrient uptake, and stress resilience. Furthermore, it explores how emerging platforms such as
Ciro Allará   +8 more
wiley   +1 more source

Design of A Flexible Liquid Metal Tactile Sensor Based on Finite Element Analysis for Pressure and Motion Detection

open access: yesAdvanced Electronic Materials, EarlyView.
In this study, a PVA sacrificial template method is proposed to fabricate microfluidic LM pressure sensors, and LM conductive pathway patterns are designed using FEA. Their study revealed that symmetric patterns and thinner microchannels significantly enhanced the pressure sensitivity of the sensor.
Zhou Zhao   +3 more
wiley   +1 more source

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