Results 61 to 70 of about 1,043,722 (370)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Attainment of Herd Immunity: Mathematical Modelling of Survival Rate [PDF]
arXiv, 2020 We study the influence of the rate of the attainment of herd immunity (HI), in the absence of an approved vaccine, on the vulnerable population. We essentially ask the question: how hard the evolution towards the desired herd immunity could be on the life of the vulnerables?
arxiv
Human Trafficking: Fighting the Hidden Crime of Modern-Day Slavery [PDF]
, 2014 The issue brief examines the link between economic insecurity in our community's most vulnerable populations and the prevalence of human trafficking.
core
Vaccination in emergencies. [PDF]
, 1999 Nongovernmental organisations (NGOs) are the main actors of vaccine delivery during complex humanitarian emergencies such as large population displacements.
Paquet, C
core +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Implementation Science, 2017 Background Individuals with severe mental illness (e.g., schizophrenia, bipolar disorder) die 10–25 years earlier than the general population, primarily from premature cardiovascular disease (CVD).
Christina Mangurian +5 more
doaj +1 more source
BMJ Open, 2020 Objective Cardiovascular disease is an underappreciated issue in prison medicine. Recent studies have revealed a higher prevalence of cardiovascular disease risk factors (CVDRFs) among individuals in prison, but the impact of incarceration on CVDRFs over
Patrick Bodenmann +6 more
doaj +1 more source
Assessing Attitudinal Barriers to Health Insurance Enrollment and Facilitation in Vulnerable Populations [PDF]
, 2017 Introduction: Homeless individuals bear a disproportionately high burden of disease. Lack of health insurance amongst homeless populations is a significant barrier to healthcare access.
Brown, Christopher
core +1 more source
Children as a Vulnerable Population
Human and Ecological Risk Assessment: An International Journal, 2005 Children are not little adults. They have unique patterns of environmental exposure and developmentally determined susceptibilities that increase their risk of disease following toxic environmental exposure. Evidence is accumulating that children's exposure to toxic chemicals in the environment is contributing to changing patterns of pediatric disease.
openaire +3 more sources
Health Status of Vulnerable Populations [PDF]
Annual Review of Public Health, 1994 The notion of risk underlying the concept of vulnerability implies that everyone is potentially vulnerable (or at risk), that is, there is always a chance of developing health problems. The risk is, however, greater for those with the least social status, social capital, and human capital resources to either prevent or ameliorate the origins and ...
openaire +3 more sources