Results 41 to 50 of about 4,133 (165)

Vulvar Diseases that Required a Biopsy: A Retrospective Study

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2021
Introduction: The vulvar area may be affected by many noninfectious conditions with similar clinical appearance, requiring a cutaneous biopsy. Our goal was to characterize the noninfectious vulvar diseases that required a biopsy in a southwestern Europe ...
Rita Bouceiro-Mendes   +4 more
doaj   +1 more source

Analysis of Age, Period and Cohort Trends in Cervical In Situ and Invasive Carcinomas for Assessing the Utility of Screening Approaches—Results From the Saarland Cancer Registry

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Cervical cancer continues to pose a significant public health burden. In Germany, prevention relies heavily on regular screening and HPV vaccination. Objective To analyze trends in cervical cancer incidence over a 50‐year period in Saarland, Germany, with a focus on cohort effects and the impact of screening programs.
Natalie Rath   +2 more
wiley   +1 more source

Photodynamic Therapy for Gynecological Diseases and Breast Cancer

open access: yesCancer Biology & Medicine, 2012
Photodynamic therapy (PDT) is a minimally invasive and promising new method in cancer treatment. Cytotoxic reactive oxygen species (ROS) are generated by the tissue-localized non-toxic sensitizer upon illumination and in the presence of oxygen.
Natashis Shishkova   +2 more
doaj   +3 more sources

GATA3 Inhibits the Expression of Viral E6/E7 Genes, and Its Expression Is Compromised During HPV‐Mediated Cervical Carcinogenesis

open access: yesJournal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT High‐risk human papillomaviruses (HPV) are the main etiological agents of cervical cancer. The viral early promoter regulates the expression of E6/E7 oncoproteins, and its transcriptional activity is positively or negatively regulated by host transcription factors (TFs) that are able to bind to the viral long control region (LCR).
Valéria Talpe‐Nunes   +11 more
wiley   +1 more source

Prognostic impact of anal cancer morphology on survival and local recurrence: A 20‐year regional cohort study

open access: yesColorectal Disease, Volume 28, Issue 7, July 2026.
Abstract Aim The relationship between macroscopic tumour morphology and clinical outcomes has previously been demonstrated for malignant melanoma and gastric cancers, but not for anal squamous cell cancer (ASCC). This study investigated the effect of the morphology of ASCC on oncological outcomes.
Alwin Puthiyakunnel Saji   +3 more
wiley   +1 more source

Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study

open access: yesBMC Cancer, 2011
Background Epigenetic regulation is an important mechanism leading to cancer initiation and promotion. Histone acetylation by histone deacetylases (HDACs) represents an important part of it.
Samartzis Nicolas   +7 more
doaj   +1 more source

The Role of Enterococcus faecium in the Synergistic Clearance of High‐Risk HPV: A Clinical Study on Cervicovaginal Microbiota Regulation

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Persistent infection with high‐risk human papillomavirus (HR‐HPV) is defined as the principal cause of cervical cancer. Given the important role of cervicovaginal microbiota in HPV acquisition and disease progression, this study aims to evaluate the clinical efficacy of the probiotic Enterococcus faecium (E.
Jun Yang   +6 more
wiley   +1 more source

Photodynamic diagnosis with methyl-5-aminolevulinate in squamous intraepithelial lesions of the vulva: Experimental research. [PDF]

open access: yesPLoS ONE, 2018
The incidence of the High-grade Squamous Intraepithelial Lesion of the vulva, formerly vulvar intra-epithelial neoplasia is progressively increasing. Today, an early detection and a precise localization of vulvar lesions are still problematic issues, due
Lea Leufflen   +6 more
doaj   +1 more source

Optical Coherence Tomography in Vulvar Intraepithelial Neoplasia

open access: yesAnnals of Oncology, 2012
Vulvar squamous cell carcinoma (VSCC) is a gynecological cancer with an incidence of two to three per 100,000 women. VSCC arises from vulvar intraepithelial neoplasia (VIN), which is diagnosed through painful punch biopsy. In this study, optical coherence tomography (OCT) is used to differentiate between normal and VIN tissue.
Wessels, R.   +7 more
openaire   +3 more sources

Anal Cancer Screening and High‐Resolution Anoscopy: What Surgeons Should Know

open access: yes
ANZ Journal of Surgery, EarlyView.
Matthew Joseph Marino   +4 more
wiley   +1 more source

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