Results 61 to 70 of about 105,429 (154)

Photodynamic Therapy for Gynecological Diseases and Breast Cancer

Cancer Biology & Medicine, 2012
Photodynamic therapy (PDT) is a minimally invasive and promising new method in cancer treatment. Cytotoxic reactive oxygen species (ROS) are generated by the tissue-localized non-toxic sensitizer upon illumination and in the presence of oxygen.
Natashis Shishkova, Olga Kuznetsova, Temirbolat Berezov   +2 more
doaj   +3 more sources

TP53 codon 47 and 72 polymorphisms show no association with HPV in Zimbabwean women living with HIV and histologically confirmed cervical and vulvar disease

Frontiers in Reproductive Health
IntroductionInteraction between HIV and human papillomavirus (HPV) increases the risk of HPV persistence. However, a few studies have explored the interplay between host genetic factors and HPV in women living with HIV (WLWH).
Oppah Kuguyo, Margaret Pascoe, Eugenie Lohmann, Takudzwa Magwaku, Diana L. T. Mukuku, Ardele Mandiriri, Nyarai Soko, Nyarai Soko, Collet Dandara, Rudo Makunike Mutasa, Megan Fitzpatrick, Joel Palefsky, Trine Rounge, Zvavahera Mike Chirenje, Racheal S. Dube Mandishora, Racheal S. Dube Mandishora   +15 more
doaj   +1 more source

Large Anogenital Bowen Disease Misdiagnosed as Chronic Eczema for Nine Years: A Case Report Highlighting the Importance of Early Biopsy

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Persistent treatment‐resistant anogenital plaques should not be repeatedly managed as chronic eczema without histopathological confirmation. Early biopsy of atypical or non‐resolving lesions facilitates timely diagnosis of Bowen disease, prevents prolonged diagnostic delay, and enables treatment before progression to invasive squamous cell ...
Shiwani Sharma Acharya, Sanket Bishokarma, Uma Giri   +2 more
wiley   +1 more source

Photodynamic therapy in vulvar intraepithelial neoplasia [PDF]

, 1970
Introduction: Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer.
Kellas-Ślęczka, Sylwia, Biniszkiewicz, Tomasz, Kozak-Darmas, Iwona, Sieroń, Aleksander, Olejek, Anita   +4 more
core  

Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study

BMC Cancer, 2011
Background Epigenetic regulation is an important mechanism leading to cancer initiation and promotion. Histone acetylation by histone deacetylases (HDACs) represents an important part of it.
Samartzis Nicolas, Imesch Patrick, Dedes Konstantin J, Samartzis Eleftherios P, Fedier André, Fink Daniel, Caduff Rosmarie, Fehr Mathias K   +7 more
doaj   +1 more source

Photodynamic diagnosis with methyl-5-aminolevulinate in squamous intraepithelial lesions of the vulva: Experimental research. [PDF]

PLoS ONE, 2018
The incidence of the High-grade Squamous Intraepithelial Lesion of the vulva, formerly vulvar intra-epithelial neoplasia is progressively increasing. Today, an early detection and a precise localization of vulvar lesions are still problematic issues, due
Lea Leufflen, Aurelie Francois, Julia Salleron, Catherine Barlier, Gilles Dolivet, Frederic Marchal, Lina Bezdetnaya   +6 more
doaj   +1 more source

Analysis of Age, Period and Cohort Trends in Cervical In Situ and Invasive Carcinomas for Assessing the Utility of Screening Approaches—Results From the Saarland Cancer Registry

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Cervical cancer continues to pose a significant public health burden. In Germany, prevention relies heavily on regular screening and HPV vaccination. Objective To analyze trends in cervical cancer incidence over a 50‐year period in Saarland, Germany, with a focus on cohort effects and the impact of screening programs.
Natalie Rath, Klaus Neis, Bernd Holleczek   +2 more
wiley   +1 more source

GATA3 Inhibits the Expression of Viral E6/E7 Genes, and Its Expression Is Compromised During HPV‐Mediated Cervical Carcinogenesis

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT High‐risk human papillomaviruses (HPV) are the main etiological agents of cervical cancer. The viral early promoter regulates the expression of E6/E7 oncoproteins, and its transcriptional activity is positively or negatively regulated by host transcription factors (TFs) that are able to bind to the viral long control region (LCR).
Valéria Talpe‐Nunes, Aline Lopes Ribeiro, Rafaella Almeida Nunes, João Simão Sobrinho, Amanda Schiersner Caodaglio, Rossana Veronica Mendonza Lopez, Thais Rocha, Maria Luiza Nogueira Dias Genta, Konstanze Schichl, Ademola Aiyenuro, John Doorbar, Laura Sichero   +11 more
wiley   +1 more source

Human papillomavirus type 16 in vulvar carcinoma, vulvar intraepithelial neoplasia, and associated cervical neoplasia.

, 1991
Vulvar intraepithelial neoplasia (VIN) is becoming more widespread and the patients are becoming still younger. Although progression to invasive vulvar carcinoma is uncommon, local recurrences are frequent and about one-quarter of the patients have ...
Hørding, U., Norrild, B, Bock, JE, Daugaard, S., Iversen, A.K.N., Knudsen, J, Daigaard, S., Knudsen, J., Bock, J.E., Hørding, U, Daugaard, S, Norrild, B., Iversen, AK   +12 more
core   +1 more source

Anogenital diseases associated with HPV infection [PDF]

Гинекология, 2015
The review examined the role of HPV in anogenital diseases. There are presented modern data on the prevalence of anal intraepithelial neoplasia (AIN), HPV infection of the anal region among women at risk (cervical intraepithelial neoplasia - CIN, vulvar -
V N Prilepskaya, N M Nazarova, L A Sulamanidze, O V Burmenskaya, D Yu Trofimov, S V Pavlovich   +5 more
doaj