Results 201 to 210 of about 61,670 (295)

Biomarker profiles in late‐life depression and Alzheimer's disease across and beyond the A/T/N framework: A scoping review

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract Depression and Alzheimer's disease (AD) frequently overlap clinically, and depressive symptoms may signal major depressive disorder, a risk factor for AD, or an early manifestation of neurodegeneration. This scoping review mapped biomarker evidence differentiating depression and AD within and beyond the amyloid/tau/neurodegeneration (A/T/N ...
Yiqi Zhu, Nikitha Damera, Ramkrishna K. Singh, Semere Bekena, Laura Kelble, Katherine McGuire, Yikun Hu, Eden Mersiehazen, Gagan Vijay, Arya Nazif, Ramana Kolady, Liwei Xiang, Xian Liu, Shaney Flores, Kaitlyn Dombrowski, Subrata Pal, Angela Hardi, Kaylin Taylor, Jean‐Francois Trani, Beau M. Ances, Eric J. Lenze, Prashanthi Vemuri, Clifford R. Jack Jr., Ronald C. Petersen, Ganesh M. Babulal   +24 more
wiley   +1 more source

A screening assay for type 2B von Willebrand factor variants using an enzyme-linked immunosorbent assay based on recombinant wild-type glycoprotein Ib and ristocetin. [PDF]

Res Pract Thromb Haemost
Pagliari MT, Baronciani L, Colpani P, Cozzi G, Seidizadeh O, Ciavarella A, Siboni SM, Peyvandi F.   +7 more
europepmc   +1 more source

Systematic pathway‐level analysis defines conserved transcriptional divergence between primary lung tumors and cell line models

Animal Models and Experimental Medicine, Volume 9, Issue 10, Page 2001-2013, October 2026.
Lung cancer cell lines diverge substantially from primary tumors at the transcriptional level. Using single‐sample gene set enrichment analysis and L1‐penalized feature selection across TCGA‐LUAD and CCLE‐LUAD, we identified five Hallmark pathways (E2F targets, G2M checkpoint, IFNγ response, coagulation, and EMT) that discriminated primary tumors from ...
Pritam Bera, Rajesh Raju, Debodipta Das
wiley   +1 more source

Endotheliopathy in CAR T-Cell Therapy: Mechanistic Insights into the VWF/ADAMTS13 Axis and the Angiopoietin-Tie2 Pathway. [PDF]

TH Open
de Bruijn S, Vangenechten I, Anguille S, Gadisseur A.   +3 more
europepmc   +1 more source

Integrated scRNA‐Seq and Spatial Transcriptomics Reveal CHPF and GPC1 as Markers of Cancer‐Associated Fibroblast–Dominant Domains in Colorectal Cancer

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Spatial heterogeneity in the colorectal cancer (CRC) tumor microenvironment (TME) is closely related to stromal organization and may influence treatment‐related features. In this study, we integrated single‐cell RNA sequencing and spatial transcriptomic data from CRC tissues to examine cancer‐associated fibroblast (CAF)‐dominant spatial ...
Yuan‐jie Liu, Qian‐wen Ye, Hui Zhang, Ning Yang, Yang Li, Jie‐pin Li   +5 more
wiley   +1 more source

Botanical, Phytochemistry, Pharmacology and Applications of Genus Heracleum: A Review

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This manuscript presents a comprehensive review of plant species in the genus Heracleum, from botanical classification and distribution to medicinal uses, phytochemistry, pharmacology, and applications, aiming to provide references for further exploration of their therapeutic value and research development.
Nan Zhang, Yuan Li, Zhi‐Yuan Guo, Ye‐Zi Ma, Miao‐Miao Xu, Dong‐Dong Zhang   +5 more
wiley   +1 more source

Disproportionate Subgaleal Hemorrhage in an Infant: Abuse or Bleeding Disorder? [PDF]

Diagnostics (Basel)
Wang CH, Lin PC, Hou JY.
europepmc   +1 more source

Long Term Follow Up of Hereditary Thrombotic Thrombocytopenic Purpura on Plasma Therapy for 9 Years: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 7.6‐year‐old boy with hTTP had fever‐induced hemorrhagic rash, MAHA, cerebral infarction, and renal impairment. After plasma therapy, symptoms were partially relieved; 9‐year follow‐up showed regular plasma transfusion was needed, with CKD Stage 3.
Dai Xiaomei, Chen Ruyue, Wu Shuang, Tang Hanyun, Lin Qiang, Li Xiaozhong   +5 more
wiley   +1 more source

The absence of ADAMTS13 improves early outcomes in an experimental model of trauma with uncontrolled hemorrhage. [PDF]

J Trauma Acute Care Surg
Sloos PH, Vermeersch L, Hameed R, Maas MAW, Delmote AS, Roelofs JJTH, Muia J, Tersteeg C, Vanhoorelbeke K, Juffermans NP, Kleinveld DJB.   +10 more
europepmc   +1 more source